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Medicine for treating coronary disease and stenocardia and its preparation method

A technique for angina pectoris and coronary heart disease, which is applied in the field of medicines for treating coronary heart disease and angina pectoris and their preparation, can solve the problems of inability to completely solve coronary stenosis, large toxic and side effects of western medicine, and many adverse reactions, and achieves significant curative effect and toxic and side effects. Low, reduced myocardial oxygen consumption and blood viscosity

Active Publication Date: 2006-11-01
XIAN CHIHO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In summary, the role of drug therapy is to relieve or reduce the attack of angina, but it cannot completely solve the problem of coronary artery stenosis
The acute attack stage of the disease can be basically controlled clinically at present, but the remission period requires long-term medication due to the long course of the disease, and the side effects of western medicine are large, and there are many adverse reactions.

Method used

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  • Medicine for treating coronary disease and stenocardia and its preparation method

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Embodiment Construction

[0039] The preparation method of Pueraria total flavonoids, hawthorn extract and gypenosides is as follows;

[0040] 1. Total flavonoids of kudzu root

[0041] This product is the ethanol extract (total flavonoids) extracted from the wild root of the leguminous plant Pueraria Iobata (Willd) Ohwi. It contains puerarin (C 21 h 20 o 9 ) shall not be less than 15.0%.

[0042] [Preparation method] get Pueraria lobata coarse powder, according to the percolation method under the item of liquid extract and extract (Chinese Pharmacopoeia 1995 edition one appendix 10), take ethanol as solvent, percolate after soaking for 2 days, collect the effluent, reduce Press to recover ethanol and condense into a thick paste, spray powder and dry to obtain.

[0043] 2. Hawthorn Extract

[0044] This product is the 70% ethanol extract of Crataegus pinnatifida Bge var.major N.E.Br. Dry at 60°C for 6 hours, containing rutin (C 27 h 30 o 16 ) shall not be less than 2.0%.

[0045] [Preparation...

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Abstract

A medicine for treating coronary heart disease and angina pectoris and a preparation method thereof. Soybean oil 5-100; beeswax 0.1-3; hydrogenated palm oil 0.4-10; soybean lecithin 0.2-5; methyl silicone oil 0.01-0.5; gelatin 8-150; glycerin 3-80; distilled water 8-150; Esters 0.01-0.8, the preparation method is to use appropriate amount of distilled water, gelatin, glycerin, and ethyl p-hydroxybenzoate to prepare glue; add quantitative beeswax and hydrogenated palm oil to soybean oil, and heat to make the above two substances in soybean oil Completely dissolve, cool, add soybean lecithin, stir well to make it uniform; then add gypenosides, hawthorn extract, and kudzu root flavonoids powder that have been passed through a 60-mesh sieve one by one, stir well to make it evenly mixed, and pass through a colloid mill for 2 times , add methyl silicone oil, let it stand, and vacuumize until the air bubbles in the liquid are basically removed, and set aside; use the gelatinized pellets that have been melted, each containing 580mg, and the thickness of the rubber is about 0.85-0.95mm, and the pellets are made by pressing.

Description

technical field [0001] The invention relates to a medicine for treating coronary heart disease and angina pectoris and a preparation method thereof. Background technique [0002] Coronary heart disease and angina pectoris refer to clinical syndromes caused by coronary insufficiency, acute and temporary myocardial ischemia and hypoxia. The principle of treatment of coronary heart disease and angina pectoris is to improve the blood supply of the coronary arteries and reduce the oxygen consumption of the myocardium, while treating atherosclerosis. Therapeutic drugs are divided into three categories: the first category is nitrate preparations, the main function is to expand the coronary arteries, reduce resistance, and increase blood flow in the coronary circulation. Ventricular volume, cardiac internal pressure, cardiac output and blood pressure, reduce cardiac preload and myocardial oxygen demand, thereby relieving angina pectoris, commonly used preparations are nitroglycerin...

Claims

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Application Information

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IPC IPC(8): A61K36/734A61K36/48A61K36/424A61K9/20A61P9/10
Inventor 任建国郭建文
Owner XIAN CHIHO PHARMA
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