Superfine powder antiseptic tissue regeneration promoting powder and preparation method thereof

A technology of Shengjisan and ultrafine powder, which is applied in powder delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. It can solve the problems of low dissolution rate of active ingredients of traditional Chinese medicine, uneven particle size of crushed particles, and inconspicuous clinical effects, etc. problems, to achieve the effect of facilitating digestion and absorption, reducing water content and particle size, and shortening the ultrafine pulverization time

Pending Publication Date: 2022-05-20
河南百草元兽药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the vast majority of Chinese veterinary medicine powders are conventionally crushed, and the crushing particle size is generally required to pass through the No. 2 pharmacopoeia sieve (the sieve aperture is 850 μm ± 29 μm); conventional veterinary medicine powders have the following disadvantages: 1. Conventional Chinese veterinary medicine powders are generally composed of multi-flavored drugs Composition, crushed particle size is not uniform, and it is difficult to control the uniformity after mixing; 2. The cell wall breaking rate of conventional Chinese veterinary medicine powder is very small, and the dissolution rate of active ingredients of Chinese medicine in livestock and poultry is very small, and the clinical effect is not obvious, resulting in waste of Chinese medicine ;3. Conventional Chinese veterinary drug powders are generally mixed in feed and fed in a large amount, resulting in poor palatability, resulting in a decrease in feed intake. Although the dosage of the drug is sufficient, the feed intake of livestock and poultry is not enough, which often seriously affects the efficacy of the drug; 4 , Contains volatile oil and components that are not resistant to high temperature are destroyed, reducing the clinical efficacy

Method used

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  • Superfine powder antiseptic tissue regeneration promoting powder and preparation method thereof

Examples

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Effect test

Embodiment 1

[0039] An ultrafine powder antiseptic Shengji powder, which is composed of the following raw materials in parts by weight: 20 parts of dried alum, 10 parts of dried blood, 10 parts of frankincense, 16 parts of myrrh, 16 parts of realgar, 16 parts of calcined gypsum, 2 parts of borneol, light Powder 2 parts.

[0040] The preparation method of the superfine powder anti-corrosion Shengji powder comprises the following steps:

[0041] (1) After weighing each component according to the weight parts of the raw material, the net system is made, and each raw material is cut into a thickness of 2mm by slicing;

[0042] (2) Vacuum-dry the slices at 60°C and 0.06MPa to a water content of 5%, and crush them to a particle size of 150 μm with a high-speed universal pulverizer;

[0043] (3) Puffing the pulverized raw material for 60s under the conditions of 3.0Mpa and 150°C;

[0044] (4) After puffing, use a vibrating mill to ultrafinely pulverize for 30 minutes at a temperature of -30° C....

Embodiment 2

[0046] An ultrafine powder antiseptic Shengji powder, which is composed of the following raw materials in parts by weight: 10 parts of dried alum, 5 parts of dried blood, 5 parts of frankincense, 8 parts of myrrh, 8 parts of realgar, 8 parts of calcined gypsum, 1 part of borneol, light Powder 1 part.

[0047] The preparation method of the superfine powder anti-corrosion Shengji powder comprises the following steps:

[0048] (1) After weighing each component according to the weight parts of the raw material, the net system is made, and each raw material is cut into a thickness of 3mm by slicing;

[0049] (2) Vacuum-dry the slices at 40°C and 0.12MPa to a water content of 8%, and crush them to a particle size of 500 μm with a high-speed universal pulverizer;

[0050] (3) Puffing the pulverized raw material for 100s under the conditions of 2.0Mpa and 120°C;

[0051] (4) After puffing, use a vibrating mill to ultrafinely pulverize for 60 minutes at a temperature of -5°C until the ...

Embodiment 3

[0053] An ultrafine powder antiseptic Shengji powder, which is composed of the following raw materials in parts by weight: 30 parts of dried alum, 15 parts of dried blood, 15 parts of frankincense, 24 parts of myrrh, 24 parts of realgar, 24 parts of calcined gypsum, 3 parts of borneol, light Powder 3 parts.

[0054] The preparation method of the superfine powder anti-corrosion Shengji powder comprises the following steps:

[0055] (1) After weighing each component according to the weight parts of the raw material, the net system is made, and each raw material is cut into a thickness of 3mm by slicing;

[0056] (2) Vacuum-dry the slices at 80°C and 0.01MPa to a water content of 7%, and crush them to a particle size of 400 μm with a high-speed universal pulverizer;

[0057] (3) Puffing the pulverized raw material for 50s under the conditions of 4.0Mpa and 140°C;

[0058] (4) After puffing, use a vibrating mill to ultrafinely pulverize for 40 minutes at a temperature of -20° C....

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Abstract

The invention discloses ultrafine powder antiseptic tissue regeneration promoting powder and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine, the ultrafine powder antiseptic tissue regeneration promoting powder comprises the following raw materials by weight: 10-30 parts of dried alum, 5-15 parts of dragon's blood, 5-15 parts of frankincense, 8-24 parts of myrrh, 8-24 parts of realgar, 8-24 parts of calcined gypsum, 1-3 parts of borneol, and 1-3 parts of calomel. The preparation method comprises the following steps: weighing the raw materials in parts by weight, cleaning and slicing; drying and crushing the slices; crushing and puffing; and finally, carrying out superfine grinding. The preservative and tissue regeneration promoting powder provided by the invention can prevent corrosion and promote tissue regeneration, astringe to stop bleeding, absorb moisture and heal the mouth; the water content and the particle size of the superfine powder prepared by the preparation method are greatly reduced, the dissolution of effective components is remarkably shortened, the bioavailability is improved, and the treatment effect can be achieved by small-dose administration.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a superfine powder anti-corrosion Shengji powder and a preparation method thereof. Background technique [0002] Skin trauma (such as trauma caused by hoof trimming, livestock aphtha, aphthous disease caused by virus infection, or hoof ulcers caused by foot-and-mouth disease, etc.) often occurs in the breeding industry, affecting the economic benefits of farmers and endangering the development of animal husbandry. And the current treatment of domestic animal skin trauma usually adopts iodine glycerin to smear, but the curative effect is extremely unsatisfactory. In addition, the environment of livestock is relatively harsh, which seriously affects the healing of wounds. [0003] At present, there are many literature reports on the treatment of traumatic wounds. For example, Bailieping ointment (patent application number 201310164727.9) is composed of 16 her...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K36/896A61K9/14A61P17/02A61P7/04A61P31/04A61P31/10A61P17/04A61K33/06A61K33/36A61K31/045A61K33/28
CPCA61K33/06A61K36/889A61K36/896A61K36/324A61K36/328A61K33/36A61K31/045A61K33/28A61K9/14A61P17/02A61P7/04A61P31/04A61P31/10A61P17/04A61K2236/15A61K2236/17A61K2300/00Y02A50/30
Inventor 王同亮张文文缑瑞霞
Owner 河南百草元兽药有限公司
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