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Antipyretic cold compress patch and preparation method thereof

A cold compress and antipyretic technology, which is applied in pharmaceutical formulas, cosmetic preparations, dressing preparations, etc., can solve problems such as no repair function, sunburned skin does not have repair function, and human skin is tanned, so as to improve Preventive ability, enhanced ability to prevent UV rays, and shortened healing time

Inactive Publication Date: 2021-03-30
拉萨迪康生物材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, antipyretic (cold compress) patches can be used in a variety of environments, such as working or traveling under strong sunlight conditions, because exposure to strong ultraviolet rays can cause tanning or even sunburn on the human skin. At present, there is no antipyretic patch that can Protects against UV rays while also repairing skin surface damage
[0005] Chinese invention patent CN104887384B discloses a smart antipyretic patch, which can obtain the temperature of the patient's forehead in real time through the temperature sensing module, and can display the temperature on the screen of the touch display module through the control module, so that The smart antipyretic patch understands the patient's body temperature during use, so that you can know the efficacy of the antipyretic patch at any time. However, the antipyretic patch can only monitor the antipyretic effect in real time, and cannot prevent ultraviolet rays. It is not suitable for patients with sunburned skin. any fixes
[0006] Chinese patent CN210903624U discloses a medical cold compress with good antipyretic and air-permeable effects. The cold compress can prevent redness, swelling and itching of the skin from blisters during the cold compress, increase the air permeability of the cold compress, and is easy to use and has a good cold compress effect. But it also cannot prevent the damage of ultraviolet rays, and it does not have the function of repairing sunburned skin.
[0007] To sum up, the prior art generally lacks a kind of antipyretic patch that can repair skin surface damage while preventing ultraviolet rays.

Method used

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  • Antipyretic cold compress patch and preparation method thereof
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  • Antipyretic cold compress patch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1 A kind of antipyretic cold compress

[0039] The antipyretic cold compress is composed of the following components and their mass percentages: 3.5% sodium polyacrylate, 15% glycerol, 0.05% aluminum glycylate, 0.05% disodium edetate, and 0.5% absolute ethanol , Menthol 0.05%, DL-Tartrate 0.05%, Nano TiO 2 0.5%, cyclomethicone 5%, dendrobium 1%, stabilizer 0.3%, Tween-20 0.05%, water 74.45%; the stabilizer is composed of valerian root extract and trehalose in a mass ratio of 15:7 .

[0040] The preparation method of described antipyretic cold compress, comprises the steps:

[0041]S1. Sodium polyacrylate, aluminum glycylate, disodium edetate, and nano-TiO 2 , placed in a stirrer and stirred at a high speed at 10000rpm for a stirring time of 5min to make mixture I;

[0042] S2. Add glycerol and dendrobium to the mixture I prepared in step S1, and stir for 5 minutes at a speed of 3000 rpm to form mixture II;

[0043] S3. Mix menthol, absolute ethanol, and ...

Embodiment 2

[0050] Embodiment 2 A kind of antipyretic cold compress

[0051] The antipyretic cold compress consists of the following components and their mass percentages: 13% sodium polyacrylate, 30% glycerol, 2% aluminum glycylate, 1.5% disodium edetate, and 5% absolute ethanol , Menthol 1%, DL-Tartrate 1.5%, Nano TiO 2 2%, cyclomethicone 20%, dendrobium 2%, stabilizer 0.6%, Tween-200.1%, water 21.3%; the stabilizer is composed of valerian extract and trehalose in a mass ratio of 20:9.

[0052] The preparation method of described antipyretic cold compress, comprises the steps:

[0053] S1. Sodium polyacrylate, aluminum glycylate, disodium edetate, and nano-TiO 2 , placed in a stirrer and stirred at a high speed at 12000rpm for a stirring time of 15min to make mixture I;

[0054] S2. Add glycerol and dendrobium to the mixture I prepared in step S1, and stir for 10 min at a speed of 5000 rpm to form mixture II;

[0055] S3. Mix menthol, absolute ethanol, and cyclomethicone, and stir a...

Embodiment 3

[0058] Embodiment 3 A kind of antipyretic cold compress

[0059] The antipyretic cold compress consists of the following components and their mass percentages: 5% sodium polyacrylate, 20% glycerol, 0.5% aluminum glycylate, 0.5% disodium edetate, and 1% absolute ethanol , Menthol 0.2%, DL-Tartrate 0.1%, Nano TiO 2 1.0%, cyclomethicone 10%, dendrobium 1%, stabilizer 0.4%, Tween-20 0.06%, water 60.24%; the stabilizer is composed of valerian root extract and trehalose in a mass ratio of 17:8 .

[0060] The preparation method of described antipyretic cold compress, comprises the steps:

[0061] S1. Sodium polyacrylate, aluminum glycylate, disodium edetate, and nano-TiO 2 , placed in a stirrer, stirred at a high speed at 10000rpm for 8 minutes, and made mixture I;

[0062] S2. Add glycerol and dendrobium to the mixture I made in step S1, and stir for 7 minutes at a speed of 3600 rpm to make mixture II;

[0063] S3. Mix menthol, absolute ethanol, and cyclomethicone, and stir at ...

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Abstract

The invention belongs to the technical field of medical product preparations, and particularly relates to an antipyretic cold compress patch and a preparation method thereof. The antipyretic cold compress patch comprises the following components in percentage by mass: 3.5 to 13 percent of sodium polyacrylate, 15 to 30 percent of glycerol, 0.05 to 2 percent of dihydroxyaluminium aminoacetate, 0.05to 1.5 percent of disodium ethylene diamine tetraacetate, 0.5 to 5 percent of absolute ethyl alcohol, 0.05 to 1 percent of menthol, 0.05 to 1.5 percent of DL-tartaric acid, 0.5 to 2 percent of nano TiO2, 5 to 20 percent of cyclomethylsilicone, 1 to 2 percent of dendrobium, 0.3 to 0.6 percent of stabilizer, 0.05 to 0.1 percent of tween and 21.3 to 74.45 percent of water. The antipyretic cold compress patch can prevent ultraviolet rays, avoids local sunburn and sunburn of a user, and has a repairing function on surface damage at the same time.

Description

technical field [0001] The invention belongs to the technical field of medical preparations, and in particular relates to an antipyretic cold compress and a preparation method thereof. Background technique [0002] Antipyretic cold compress is a commonly used medical device, which has the effect of cooling down fever and cold compress physiotherapy, and can relieve fever, headache, toothache, pain and heat symptoms caused by muscle sprain. [0003] The antipyretic (cold compress) patches currently on the market all evaporate excess heat in the body through the vaporization of water in the gel, thereby achieving the effect of lowering body temperature and allowing patients to cool down safely. It belongs to physical cooling products, and is widely used for fever because of its fast cooling effect, good cooling effect, safety and non-toxic side effects. [0004] Although there are many antipyretic (cold compress) patches on the market, most of them can only play a single phys...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/02A61K8/9794A61K8/29A61K8/891A61K8/9789A61K8/60A61Q17/04A61Q19/00A61F7/02
CPCA61F7/02A61F2007/0261A61F2007/0282A61K8/0208A61K8/29A61K8/60A61K8/891A61K2800/413A61K2800/52A61K2800/592A61Q17/04A61Q19/004A61K8/9789A61K8/9794
Inventor 周鹏张凯叶勇向冲彭飞
Owner 拉萨迪康生物材料有限公司
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