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Carbon fiber/carbon composite material C-shaped artificial tracheal stent with high bioactivity and preparation method thereof

A carbon composite material, tracheal stent technology, applied in the direction of stents and other directions, can solve the problems of high surface hardness and low friction coefficient, etc.

Pending Publication Date: 2021-01-08
HUNAN TANKANG BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the defects of the artificial tracheal stent in the prior art, the object of the present invention is to provide a carbon fiber / carbon composite C-shaped artificial tracheal stent with high biological activity, which is made of carbon fiber / carbon composite material and has good Excellent biocompatibility and mechanical properties, high surface hardness, small friction coefficient, not easy to break, can block the shedding of carbon-based particles, avoid black skin effect, filled with biological activity, has good biocompatibility, and The internal communication gap is convenient for blood supply, and has a similar elastic modulus to cartilage. When it is docked with the tracheal port, the biomechanical properties are highly consistent, and biological fixation can be realized, especially its structure similar to the tracheal cartilage ring. Through C-shaped opening, retractable and expandable during breathing, satisfying physiological functions

Method used

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  • Carbon fiber/carbon composite material C-shaped artificial tracheal stent with high bioactivity and preparation method thereof
  • Carbon fiber/carbon composite material C-shaped artificial tracheal stent with high bioactivity and preparation method thereof
  • Carbon fiber/carbon composite material C-shaped artificial tracheal stent with high bioactivity and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0062] 1) First twist 2 bundles of 1k into fiber ropes, and then use 16 carbon fiber ropes to weave into a 6mm wide carbon fiber pipe belt with a pipe braiding machine, and the pipe wall thickness is 0.2mm;

[0063] 2) Fill the inner cavity of the carbon fiber tube and belt structure with polyethylene particles, reserve a fixed hole with a diameter of 1.0 mm by means of a mold, and carry out warm pressing molding. , made into a hollow ribbon structure, that is, a C-shaped artificial trachea stent blank;

[0064] 3) After cooling down, remove the mold, heat up to 80°C again, and take out the softened polyethylene material in the inner cavity of the C-shaped artificial tracheal stent blank;

[0065] 4) Dense carbon matrix of the shaped C-shaped artificial trachea stent blank, and the densified carbon matrix adopts a chemical vapor deposition process. The flow ratio of methane and hydrogen is 1:0.5, and the deposition is 80h;

[0066] 5) Processing such as cutting ends;

[006...

Embodiment 2

[0073] 1) First, 24 bundles of 3k carbon fiber bundles are woven into 8mm wide carbon fiber tube belts with a tube braiding machine, and the tube wall thickness is 0.3mm;

[0074] 2) Fill the inner cavity of the carbon fiber tube-belt structure with polystyrene particles, reserve a fixed hole with a diameter of 0.5 mm by means of a mold, and carry out warm-press molding, the conditions of the warm-press molding are: the temperature is 230 ° C, the time For 5h, a hollow ribbon structure is made, that is, a C-shaped artificial trachea stent blank;

[0075] 3) After cooling down, remove the mold, heat up to 100°C again, and take out the softened polystyrene material in the inner cavity of the C-shaped artificial tracheal stent blank;

[0076] 4) Dense carbon matrix of the shaped C-shaped artificial trachea stent blank, and the densified carbon matrix adopts a chemical vapor deposition process, and the specific process is: put the carbon fiber preform into a deposition furnace, an...

Embodiment 3

[0085] 1) First twist 2 bundles of 6k carbon fiber bundles into fiber ropes, and then use 12 carbon fiber ropes to weave into 4mm wide carbon fiber pipe belts with a tubular braiding machine;

[0086] 2) Fill the inner cavity of the carbon fiber tube-belt structure with polystyrene particles, and perform warm-press molding with the aid of a mold. The conditions of the warm-press molding are as follows: the temperature is 230° C. and the time is 5 hours to form a hollow-core ribbon structure, That is, the C-shaped artificial trachea stent blank;

[0087] 3) After cooling down, remove the mold, heat up to 100°C again, and take out the softened polystyrene material in the inner cavity of the C-shaped artificial tracheal stent blank;

[0088] 4) Dense carbon matrix of the shaped C-shaped artificial trachea stent blank, and the densified carbon matrix adopts a chemical vapor deposition process, and the specific process is: put the carbon fiber preform into a deposition furnace, and...

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Abstract

The invention discloses a carbon fiber / carbon composite material C-shaped artificial tracheal stent with high biological activity and a preparation method thereof. The C-shaped artificial tracheal stent is composed of a single C-shaped tracheal stent unit, or is composed of two or more C-shaped tracheal stent units which are combined side by side or assembled into a continuous hollow tubular structure with an axial notch in the side wall. The main body of the C-shaped tracheal stent unit is a U-shaped or pear-shaped hollow banded structure , and the hollow is filled with bioactive materials. The tracheal stent has good biocompatibility and mechanical properties, high surface hardness and small friction coefficient, has a communicated space for blood supply, has a similar elastic modulus tocartilage, has a high goodness of fit with the biomechanical property of a tracheal port, particularly it is similar to a tracheal cartilage ring structure, and during the breathing process, througha C-shaped opening,the tracheal stent can be retracted or expanded to meet physiological functions.

Description

technical field [0001] The invention relates to an artificial trachea bracket, in particular to a C-shaped artificial trachea bracket composed of carbon fiber / carbon composite material, and belongs to the technical field of biological structure repair. Background technique [0002] Clinically, the use of artificial materials for reconstruction of long trachea due to tumors and trauma has become an inevitable trend. However, due to the complexity of the tracheal tissue environment, there are many requirements for substitutes, which poses many challenges to artificial trachea materials. For example, the implantation in the body cannot achieve biological fusion and fixation with the body, and the port is improperly connected, which is accompanied by the risk of falling off and leakage. Large, the rejection reaction with the surrounding tissue leads to severe stenosis, infarction, etc., tracheal dilatation and recovery of systolic function during breathing. [0003] In the prio...

Claims

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Application Information

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IPC IPC(8): A61F2/82C04B35/83C04B35/524
CPCA61F2/82C04B35/83C04B35/524C04B2235/48C04B2235/5248C04B2235/422C04B2235/427C04B2235/656C04B2235/6567C04B2235/658A61F2002/821
Inventor 谭周建张翔王斌刘波蔡志霞
Owner HUNAN TANKANG BIOTECH CO LTD
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