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Preparation method and application of coated granules

A technology for coating granules and polyethylene glycol, which is used in the fields of food, feed processing, and pharmaceuticals, can solve problems such as the influence of enzyme activity or bacterial activity, the inability to isolate various materials, and the influence of activity and stability, so as to improve activity and stability. Stability, good processing stability, low production cost effect

Pending Publication Date: 2020-12-22
珠海天凯生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, water or organic solvents are usually used in the coating process. When water is used as a solvent, the coating process takes a long time and requires a higher temperature to dry, which greatly reduces the effective activity.
If the research solvent is used, the organic solvent itself will affect the activity of the enzyme or the activity of the bacteria and make it inactivated. Therefore, it is not suitable to use an organic solvent for the enzyme or live bacteria.
[0003] In addition, the existing coating processing method is generally prepared by making the material into pellets, and then coating a layer of film on the surface of the pellets by spray coating method. This method is complicated in process and high in cost; especially for various The compound formula of the material cannot isolate various materials from each other, which seriously affects the activity and stability of each material in the compound formula

Method used

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  • Preparation method and application of coated granules
  • Preparation method and application of coated granules
  • Preparation method and application of coated granules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] This example provides a kind of coated microelement granules (applied to pig feed), prepared according to the following process, and the specific formula is as follows:

[0027] Names of raw materials and auxiliary materials parts by weight Ferrous Sulfate Monohydrate 20 copies Copper Sulfate Pentahydrate 10 copies Manganese Sulfate Monohydrate 10 copies Zinc Sulfate Monohydrate 10 copies Sodium Selenite 5% 1 copy Potassium iodate 5% 1 copy Chromium picolinate 1.2% 1 copy Cobalt Sulfate Monohydrate 5% 2 copies stearic acid 10 copies palm oil 25 copies Glyceryl behenate 5 copies Hypromellose (K4M) 5 copies

[0028] (1) Weigh the above-mentioned granulation materials, glyceryl behenate, hypromellose, and heat-sensitive materials, place them in a mixer, and mix them for 10 minutes to obtain uniformly mixed materials;

[0029] (2) Rolling and granulating the uniformly mixed mat...

Embodiment 2

[0031] This embodiment provides a coated composite enzyme granule, based on the above preparation process, specifically as follows:

[0032] Names of raw materials and auxiliary materials parts by weight Xylanase 18 copies cellulase 10 copies protease 10 copies amylase 10 copies Lipase 1 copy Mannanase 1 copy stearic acid 20 copies polyethylene glycol 4000 15 copies Glyceryl behenate 10 copies Hypromellose (K100M) 0.5 parts Hypromellose (E5) 4.5 servings

[0033] (1) Weigh the above-mentioned granulation materials, glyceryl behenate, hypromellose, and heat-sensitive materials, place them in a mixer, and mix them for 20 minutes to obtain uniformly mixed materials;

[0034] (2) Rolling and granulating the uniformly mixed material, the rolling time is 30 minutes, the temperature is controlled at 60° C., and slow-release granules are obtained by extrusion. Particles of 0.3-1.2 mm are collec...

Embodiment 3

[0036] This embodiment provides a kind of coated vitamin granule, which is prepared by the following process, specifically as follows:

[0037]

[0038]

[0039] (1) Weigh the above-mentioned granulation materials, glyceryl behenate, hypromellose, and heat-sensitive materials, place them in a mixer, and mix them for 10 minutes to obtain uniformly mixed materials;

[0040] (2) The homogeneously mixed material is subjected to rolling granulation, the rolling time is 60 minutes, the temperature is controlled at 60° C., and slow-release granules are obtained by extrusion. Particles of 0.3-1.2 mm are collected by sieving to obtain sieved particles.

[0041] Particles of 0.3-1.2 mm are collected by sieving to obtain sieved particles.

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Abstract

The invention belongs to the technical field of food, medicine and feed processing, and discloses a preparation method and application of the coated granules. The preparation method of the coated granules comprises the following steps: (1) weighing main granulation raw materials and auxiliary materials (including glyceryl behenate, hydroxypropyl methylcellulose and a heat-sensitive material), andcarrying out mixing to obtain a mixed material; and (2) performing rolling granulation on the mixed material prepared in the step (1), and carrying out screening so as to obtain the coated granules. Being adopted, the preparation method is capable of avoiding direct contact and mutual influence of the various materials, such as foods, medicines and feeds, in the coated granules, thereby greatly shortening high-temperature time of the materials; and thus, the coated granules are endowed with good processing stability and storage stability as well as prolonged shelf life. In addition, the raw materials can be slowly and continuously released so as to have utilization rate improved. The preparation method can be applied to preparation of foods, medicines and feeds.

Description

technical field [0001] The invention belongs to the technical field of food, medicine and feed processing, and in particular relates to a preparation method and application of coated granules. Background technique [0002] In the production of food, medicine or feed, it is often necessary to add enzymes, live bacteria, oxides, organic acids, extracts, vitamins, trace elements, etc., due to its own stability or / and stability to other materials in contact with the production process Sexuality will be affected, and coating is usually used to improve stability. Acid, alkali, temperature and other factors will also have a greater impact on enzymes and live bacteria, and coating treatment is the best choice. However, water or an organic solvent needs to be used in the usual coating process. When water is used as a solvent, the coating process takes a long time and requires a higher temperature to dry, which greatly reduces the effective activity. If the research solvent is used,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K20/20A23K20/158A23K20/163A23K40/10A23K50/30A23P10/20A23L29/00A23L29/262A23L33/15A23L33/155A23L33/175A23L3/3517A23L3/3562A23L3/3508A61K9/16A61K47/38A61K47/14
CPCA23K20/30A23K20/158A23K20/163A23K40/10A23K50/30A23P10/20A23L29/04A23L29/035A23L29/06A23L29/262A23L33/15A23L33/155A23L33/175A23L3/3517A23L3/3562A23L3/3508A61K9/1652A61K9/1617A23V2002/00A23V2200/228A23V2250/1886A23V2250/1942A23V2250/51088A23V2200/30A23V2250/192A23V2250/702A23V2250/7042A23V2250/7044A23V2250/7052A23V2250/706A23V2250/7056A23V2250/708A23V2250/7106A23V2250/712A23V2250/063A23V2250/0632A23V2250/0648A23V2250/18
Inventor 张晓明周序诚麦耀权张平谭垚婷沈黎江黄家俊
Owner 珠海天凯生物科技有限公司
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