Formula and production process of sulfur ointment

An ointment and formulation technology, applied in the field of sulfur ointment, can solve the problems of short drug action time, poor drug release, peeling, cracking, etc.

Inactive Publication Date: 2020-10-30
ANHUI AIKEER PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Sulfur ointment can cure chronic inflammation of the skin. Existing sulfur ointment drugs have poor drug release and poor absorption. After use, the skin is dry, even peeling and cracked, and the drug action time is short.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A kind of formula of sulfur ointment, its raw material is as follows by weight: 8 parts of sublimated sulfur, 12 parts of zinc oxide, 8 parts of medicinal powder extract, 20 parts of base material, 7 parts of clindamycin hydrochloride, 5 parts of metronidazole and the remainder of water;

[0023] The medicinal powders of the medicinal powder extracts are mugwort, angelica, calamus, herb, cork, coix seed, pepper, berberine and licorice;

[0024] The base material is light liquid paraffin, glyceryl monostearate, yellow vaseline, stearyl alcohol, 1,3-propylene glycol, 15 ceteareth-glyceryl stearate, citric stearate Mixture of glycerides and water.

[0025] Specifically, by weight, light liquid paraffin in the base material is 15%, glyceryl monostearate is 2%, yellow petrolatum is 20%, stearyl alcohol is 10%, 1,3-propylene glycol is 8 %, 15 ceteareth-glyceryl stearate is 23%, glyceryl stearate citrate is 5% and balance water.

[0026] Specifically, the preparation method...

Embodiment 2

[0035] A kind of formula of sulfur ointment, its raw material is as follows by weight: 10 parts of sublimated sulfur, 12 parts of zinc oxide, 10 parts of medicinal powder extract, 22 parts of base material, 10 parts of clindamycin hydrochloride, 8 parts of metronidazole and the remainder of water;

[0036] The medicinal powders of the medicinal powder extracts are mugwort, angelica, calamus, herb, cork, coix seed, pepper, berberine and licorice;

[0037] The base material is light liquid paraffin, glyceryl monostearate, yellow vaseline, stearyl alcohol, 1,3-propylene glycol, 15 ceteareth-glyceryl stearate, citric stearate Mixture of glycerides and water.

[0038] Specifically, by weight, light liquid paraffin in the base material is 15%, glyceryl monostearate is 5%, yellow petrolatum is 22%, stearyl alcohol is 10%, 1,3-propanediol is 10% %, 15 ceteareth-glyceryl stearate is 25%, stearic acid citrate glyceryl is 6% and the water of balance.

[0039] Specifically, the prepara...

Embodiment 3

[0048] A kind of formula of sulfur ointment, its raw material is as follows by weight: 12 parts of sublimated sulfur, 14 parts of zinc oxide, 13 parts of medicinal powder extract, 25 parts of base material, 13 parts of clindamycin hydrochloride, 9 parts of metronidazole and the remainder of water;

[0049]The medicinal powders of the medicinal powder extracts are mugwort, angelica, calamus, herb, cork, coix seed, pepper, berberine and licorice;

[0050] The base material is light liquid paraffin, glyceryl monostearate, yellow vaseline, stearyl alcohol, 1,3-propylene glycol, 15 ceteareth-glyceryl stearate, citric stearate Mixture of glycerides and water.

[0051] Specifically, by weight, the light liquid paraffin in the base material is 15%, glyceryl monostearate is 2%, yellow petrolatum is 20%, stearyl alcohol is 16%, 1,3-propanediol is 13%. %, 15 ceteareth-glyceryl stearate is 23%, stearic acid citrate glyceryl is 6% and the water of balance.

[0052] Specifically, the pre...

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PUM

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Abstract

The invention discloses a formula of a sulfur ointment. The formula comprises the following raw materials in parts by weight: 8-12 parts of sublimed sulfur, 12-14 parts of zinc oxide, 8-13 parts of amedicinal powder extract, 20-25 parts of a base material, 7-13 parts of clindamycin hydrochloride, 5-9 parts of metronidazole and the balance of water. The medicinal powder extract which comprises artemisia argyi, angelica dahurica, acorus calamus, atractylodes lancea, phellodendron, coix seed, Sichuan pepper, coptis chinensis and liquorice is added, so that the sulfur ointment has the effects ofresisting bacteria, expelling pus, promoting blood circulation, removing blood stasis and diminishing swelling, and the effects of drug release and transdermal absorption are improved; zinc oxide hasconvergence and protection effects; sublimed sulfur has the effects of killing bacteria, fungi and mites, and can soften epidermis and dissolve cutin; the sulfur ointment has stability, has a water retention effect on skin, prevents loss of effective components of medicines, and prolongs the action time of the medicines.

Description

technical field [0001] The invention relates to the technical field of sulfur ointment, in particular to a formula of sulfur ointment and a production process thereof. Background technique [0002] Sulfur ointment can cure chronic inflammation of the skin. Existing sulfur ointment medicines have the disadvantages of poor drug release and poor absorption effect, dry skin after use, and even peeling and cracking, and short drug action time. For this reason, we propose a formula of sulfur ointment and its production process. Contents of the invention [0003] The purpose of the present invention is in order to solve the shortcoming that exists in the prior art, and proposes a kind of formula of sulfur ointment and its production technology. [0004] In order to achieve the above object, the present invention adopts the following technical solutions: [0005] A kind of formula of sulfur ointment, its raw material is as follows by weight: 8-12 parts of sublimated sulfur, 12-1...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61K47/10A61K47/14A61P17/00A61K9/06A61K31/4164A61K31/7056A61K33/04A61K33/30
CPCA61K9/06A61K31/4164A61K31/7056A61K33/04A61K33/30A61K36/232A61K36/282A61K36/284A61K36/484A61K36/718A61K36/756A61K36/758A61K36/888A61K36/8994A61K47/10A61K47/14A61K2236/331A61K2236/51A61P17/00A61K2300/00
Inventor 盛暑溧
Owner ANHUI AIKEER PHARMA CO LTD
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