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Quick-patching cold-compressing nano-gel, prepared method thereof and quick-patching cold-compressing nano-gel patch

A cold compress gel paste, nanotechnology, applied in the field of nano-speed cold compress gel and its preparation, nano-speed cold compress gel paste, can solve the problems of slow onset, short duration, long use time, etc., to achieve effective The effect of stable ingredients, high permeability and absorption rate, and no toxic side effects

Active Publication Date: 2020-05-08
SHAANXI PANLONG PHARMACEUTICAL GROUP LIMITED BY SHARE LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Oral painkillers are used throughout the body, which can easily cause side effects
The traditional cold compresses currently commonly used mostly use macromolecular pharmaceutical ingredients, which are absorbed through the skin and only reach the muscle layer. The general onset time is about 120 minutes, and the duration is about 1h-2h. It needs to be used continuously for 1-3 days. It has the disadvantages of being unable to directly reach the lesion, slow onset, short duration, and long use time, etc.

Method used

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  • Quick-patching cold-compressing nano-gel, prepared method thereof and quick-patching cold-compressing nano-gel patch
  • Quick-patching cold-compressing nano-gel, prepared method thereof and quick-patching cold-compressing nano-gel patch
  • Quick-patching cold-compressing nano-gel, prepared method thereof and quick-patching cold-compressing nano-gel patch

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The nano-quick cold compress gel of the present embodiment, the raw material comprises the following components by weight: peppermint extract 20g, wintergreen extract 10g, white fungus extract 30g, castor oil 40g; described peppermint extract, wintergreen extract and white fungus The form of the extract is powder, and the particle size of the powder is 2nm-6nm;

[0028] The preparation method of the nano-quick cold compress gel of the present embodiment comprises the following steps:

[0029] Step 1, preparing peppermint extract, wintergreen extract and white fungus extract by conventional water extraction and spray drying;

[0030] Step 2, the peppermint extract, wintergreen extract and white fungus extract are all processed by conventional supramolecular technology to obtain a powder with a particle size of 2nm to 6nm, and mixed uniformly;

[0031] Step 3, wrapping the mixed powder in step 2 with castor oil and a surfactant by conventional water-in-oil treatment to o...

Embodiment 2

[0033] The nano-quick cold compress gel of the present embodiment, the raw material comprises the following components by weight: peppermint extract 15g, wintergreen extract 12g, white fungus extract 35g, castor oil 30g; described peppermint extract, wintergreen extract and white fungus The form of the extract is powder, and the particle size of the powder is 6nm-9nm;

[0034] The preparation method of the nano-quick cold compress gel of the present embodiment comprises the following steps:

[0035] Step 1, preparing peppermint extract, wintergreen extract and white fungus extract by conventional water extraction and spray drying;

[0036] Step 2, the peppermint extract, wintergreen extract and white fungus extract are all processed by conventional supramolecular technology to obtain a powder with a particle size of 6nm to 9nm, and mixed uniformly;

[0037] Step 3, wrapping the mixed powder in step 2 with castor oil and a surfactant by conventional water-in-oil treatment to o...

Embodiment 3

[0039] The nano-quick cold compress gel of the present embodiment, the raw material comprises the following components by weight: peppermint extract 25g, wintergreen extract 8g, white fungus extract 25g, castor oil 50g; described peppermint extract, wintergreen extract and white fungus The form of the extract is powder, and the particle size of the powder is 9nm-15nm;

[0040] The preparation method of the nano-quick cold compress gel of the present embodiment comprises the following steps:

[0041] Step 1, preparing peppermint extract, wintergreen extract and white fungus extract by conventional water extraction and spray drying;

[0042] Step 2, the peppermint extract, wintergreen extract and white fungus extract are all processed by conventional supramolecular technology to obtain a powder with a particle size of 9nm to 15nm, and mixed uniformly;

[0043] Step 3, wrapping the mixed powder in step 2 with castor oil and a surfactant by conventional water-in-oil treatment to ...

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Abstract

The invention discloses quick-patching cold-compressing nano-gel. The nano-gel contains the following raw material components in parts by weight: 10-30 parts of a mint extract, 5-15 parts of a holly extract, 20-40 parts of a white fungus extract and 20-60 parts of castor oil. Besides, the invention further provides a method for preparing the cold-compressing nano-gel and a quick-patching cold-compressing nano-gel patch containing the cold-compressing nano-gel. The quick-patching cold-compressing nano-gel can suspend hierarchically in tissues of a human body and rapidly take effect after reaching a lesion and then can be continuously absorbed, so that the quick-patching cold-compressing nano-gel has the effects of deeply relieving pain and durably resisting inflammation and further has goodeffects on treatment of osteoarthritis of muscles, bones and knees; by virtue of ultramicro molecular effective ingredients, the quick-patching cold-compressing nano-gel can penetrate skin and periostea and directly reach the lesion, the onset time is 10min-30min, and the duration time is 6h-10h; and by taking plant extracts as main ingredients, the quick-patching cold-compressing nano-gel is notmetabolized through livers and kidneys and has no toxic and side effects and dependence.

Description

technical field [0001] The invention belongs to the technical field of cold compress gel, and in particular relates to a nano-quick cold compress gel and a preparation method thereof, and a nano-quick cold compress gel patch. Background technique [0002] Chronic soft tissue injury inflammation inside and outside the shoulder joint occurs mostly in people aged 40 to 50, and women patients are more than men. Mainly manifested as pain in the shoulder, with or without a history of trauma and cold; limited shoulder joint movement: flexion and extension, abduction, internal rotation, external rotation, life manifestations: difficulties in combing hair, dressing, washing face and tying shoelaces; The pain was limited to a certain point or area; the physical examination found narrowing of the shoulder joint space, limited mobility, and muscle atrophy; X-rays showed osteoporosis and bone calcification. [0003] The current method for treating chronic soft tissue injury inflammation...

Claims

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Application Information

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IPC IPC(8): A61F7/02A61K36/534A61P19/02A61P29/00
CPCA61F7/02A61K36/534A61K36/185A61K36/07A61P19/02A61P29/00A61F2007/0263A61F2007/0282A61F2007/0203A61F2007/0226A61K2300/00Y02A50/30
Inventor 张德柱谢晓林
Owner SHAANXI PANLONG PHARMACEUTICAL GROUP LIMITED BY SHARE LTD
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