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Preparation method of medium-and long-chain structured lipid composition for nutritional treatment of breast diseases

A technology for structural lipids and breast diseases, applied in the field of lipid synthesis, can solve the problems of high consumption, undeveloped medium/long chain lipids, and complicated preparation process of medium and long chain lipids, so as to reduce the consumption of energy and time, The effect of suppressing breast disease, low cost, time-consuming and energy-consuming

Active Publication Date: 2019-11-08
河北康睿达脂质有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the preparation of the oil phase in this invention consumes a lot of energy and time. In addition, in the process of preparing the primary emulsion, the oil phase is added to the water phase, usually resulting in a water-in-oil type, resulting in agglomeration, which requires a lot of energy and time for stirring. or cutting, which increases the cost, time and energy consumption of production. In addition, the absorption of physical mixed medium / long chains in the body still maintains the original absorption path, and the respective characteristics of medium / long chains have not been brought into play.
[0005] Aiming at the complex, time-consuming, expensive preparation process of medium- and long-chain lipids, and unclear nutrition therapy, a method for preparing medium- and long-chain structured lipid compositions that integrates energy and nutrition therapy should be found, so that the method is simple , convenient and cheap, and the medium and long chain structure lipid composition prepared by the above preparation method can be used for the treatment of breast diseases

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A method for preparing a medium-long-chain structured lipid composition for nutritional treatment of breast diseases, comprising the following steps:

[0026] (1) 10 parts by weight of medium-chain fatty acid triglycerides extracted from palm kernel oil, 10 parts by weight of long-chain fatty acid triglycerides extracted from grape seed oil, 5 parts by weight of conjugated linoleic acid glycerides and 6 parts by weight Parts by weight of β-sitosterol were added to a closed reactor equipped with 435 lipase and DF15 lipase and equipped with a lipase collection device to carry out transesterification reaction, the reaction temperature was 40° C., and the reaction time was 15 hours. Among them, the addition of 435 lipase is 4.5% of the total weight of medium-chain fatty acid triglycerides and long-chain fatty acid triglycerides, and the addition of DF15 lipase is the total weight of medium-chain fatty acid triglycerides and long-chain fatty acid triglycerides. 0.6%. After ...

Embodiment 2

[0030] A method for preparing a medium-long-chain structured lipid composition for nutritional treatment of breast diseases, comprising the following steps:

[0031] (1) 72 parts by weight of medium-chain fatty acid triglycerides extracted from palm kernel oil, 78 parts by weight of long-chain fatty acid triglycerides extracted from grape seed oil, 14 parts by weight of conjugated linoleic acid glycerides and 12 parts by weight Add stigmasterol in parts by weight to a closed reactor equipped with 435 lipase and DF15 lipase and equipped with a lipase collection device to carry out transesterification reaction, the reaction temperature is 60° C., and the reaction time is 6 hours. Among them, the addition of 435 lipase is 7% of the total weight of medium-chain fatty acid triglycerides and long-chain fatty acid triglycerides, and the addition of DF15 lipase is the total weight of medium-chain fatty acid triglycerides and long-chain fatty acid triglycerides. 2%. After cooling down...

Embodiment 3

[0035] A method for preparing a medium-long-chain structured lipid composition for nutritional treatment of breast diseases, comprising the following steps:

[0036] (1) 28 parts by weight of medium-chain fatty acid triglycerides extracted from palm kernel oil, 32 parts by weight of long-chain fatty acid triglycerides extracted from grape seed oil, 7 parts by weight of conjugated linoleic acid glycerides and 9 parts by weight Add campesterol in parts by weight to a closed reactor equipped with 435 lipase and DF15 lipase and equipped with a lipase collection device to carry out transesterification reaction, the reaction temperature is 50° C., and the reaction time is 10 h. Among them, the addition of 435 lipase is 6% of the total weight of medium-chain fatty acid triglycerides and long-chain fatty acid triglycerides, and the addition of DF15 lipase is the total weight of medium-chain fatty acid triglycerides and long-chain fatty acid triglycerides. 1.5%. After cooling down, go...

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Abstract

The invention provides a preparation method of medium-and long-chain structured lipid composition for nutritional treatment of breast diseases, and relates to the field of lipid synthesis. The preparation method includes the steps that conjugated linoleic acid, medium-chain triglycerides, long-chain triglycerides, conjugated linoleic acid glyceride and phytosterol are used as raw materials, an ester exchange reaction is carried out in a reactor, the pretreatment step is carried out, and medium-and long-chain triglyceride is obtained; after further treatment, the medium-and long-chain triglyceride is mixed with silica, N-acetylneuraminic acid, beta-hydroxy-beta- methylbutyrate calcium, konjac glucomannan, mangosteen extracts, elderberry and yeast beta- glucan, and the medium-and long-chainstructured lipid composition is prepared. The preparation method is simple, convenient and cheap; and meanwhile, the medium-and long-chain structured lipid composition prepared by the preparation method can be used for nutritional treatment of breast diseases.

Description

[0001] This application relies on and claims the priority of Chinese patent application 201910340193.8 filed on April 25, 2019, the entire contents of which are hereby incorporated by reference. technical field [0002] The invention relates to the field of oil synthesis, in particular to a method for preparing a medium-long chain structure lipid composition for nutritional treatment of breast diseases. Background technique [0003] Breast cancer is a malignant tumor that occurs in the glandular epithelial tissue of the breast. It usually occurs in women. Breast cancer in situ is not fatal, but because breast cancer cells lose the characteristics of normal cells, the connections between cells are loose and easy to fall off. Cancer cells Once detached, free cancer cells can spread throughout the body with blood or lymph fluid, forming metastases and threatening life. For breast cancer, the clinical manifestations of different age groups have different characteristics. Unmarri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/12A23L33/125A23L33/10A23L33/105A23P10/30
CPCA23L33/12A23L33/125A23L33/10A23L33/105A23P10/30A23V2002/00A23V2200/30A23V2200/224A23V2250/1942A23V2250/1944A23V2250/21A23V2250/5066A23V2250/5058A23V2300/26A23V2300/48A23V2300/10
Inventor 刘宝华孙秀云苑海鹏苑海祥王延荣刘宪军来创业苑洪德
Owner 河北康睿达脂质有限公司
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