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Application of apios americana medikus extract in preparation of food or medicine for reducing weight, resisting tumor and improving immunity

An extract and anti-tumor technology, which is applied in the field of medicine, can solve the problem that the weight-loss activity of bean taro flower polysaccharides is rarely reported, and achieve the effect of preventing obesity and related chronic diseases with remarkable effects and extensive effects

Active Publication Date: 2019-07-09
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, at present, many nutrition and health food researchers are very concerned about the research and topics related to the occurrence and prevention of obesity and chronic diseases, but there are few reports on the weight loss activity of taro flower polysaccharides

Method used

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  • Application of apios americana medikus extract in preparation of food or medicine for reducing weight, resisting tumor and improving immunity
  • Application of apios americana medikus extract in preparation of food or medicine for reducing weight, resisting tumor and improving immunity
  • Application of apios americana medikus extract in preparation of food or medicine for reducing weight, resisting tumor and improving immunity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-2

[0072] Embodiment 1-2, the effect of taro flower polysaccharide on fat, liver and other organ indexes of obese mice;

[0073] The mice in Example 1-1 after 12 weeks of intragastric administration were fasted for 24 hours, weighed, and the mice were killed by cervical dislocation after taking blood from the orbit, and the fat around the kidneys and epididymis was taken, and the heart, liver, and spleen were quickly removed , kidney, brown fat and other tissues and record the weight, the specific data are shown in Table 1-1.

[0074] Table 1-1 The effect of taro flower polysaccharide intervention on the organ index of mice

[0075]

[0076] According to Table 1-1, it can be seen that the intervention of taro flower polysaccharide can alleviate the decline of liver index in obese mice induced by high-fat diet, and can significantly reduce the peritesticular fat and perirenal fat index in obese mice, compared with the high-fat control group Bija flower polysaccharide intervent...

Embodiment 1-3

[0077] Embodiment 1-3, the influence of taro flower polysaccharide on obese mice serum triglyceride (TG), total cholesterol (TC), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) content;

[0078] The mice in Example 1-1 after 12 weeks of gavage were fasted for 24 hours, and the mice were killed by cervical dislocation after taking blood from the eye sockets. The blood samples were centrifuged at 1500 rpm for 15 minutes, and the serum was taken for preservation and analyzed by a Toshiba automatic biochemical analyzer. The content of triglyceride and total cholesterol in the medium was measured, and the specific data are shown in Table 1-2.

[0079] Table 1-2 Effect of the intervention of taro flower polysaccharide on the serum indexes of mice

[0080]

[0081] According to Table 1-2, it can be seen that high-dose taro flower polysaccharide intervention can reduce the total cholesterol content in the serum of obese mice induced by high-fat diet, and both t...

Embodiment 1-4

[0082] Embodiment 1-4, the effect of taro flower polysaccharide on the content of alanine aminotransferase and aspartate aminotransferase in the liver of obese mice;

[0083] Mice after 12 weeks of intragastric administration in Example 1-1 were fasted for 24h, weighed, and the mice were killed by cervical dislocation after blood was taken from the orbit, and the liver of the mice was measured according to the alanine aminotransferase content assay kit (Nanjing Jiancheng Biotechnology Co., Ltd.). Engineering Research Institute) and Aspartate Aminotransferase Content Assay Kit (Nanjing Jiancheng Bioengineering Research Institute) instructions for determination.

[0084] according to Figure 1-2 and Figure 1-3 It can be seen that compared with the low-fat control group, the content of alanine aminotransferase and aspartate aminotransferase in the liver of mice in the high-fat group increased significantly, and different doses of taro flower polysaccharides could significantly ...

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Abstract

The invention relates to the field of medicine, in particular to application of an apios americana medikus extract in preparation of food or medicine for reducing the weight, resisting the tumor and improving the immunity. The apios americana medikus extract is prepared from apios americana medikus flower polysaccharide, an apios americana medikus flower ethyl alcohol extract, an apios americana medikus leaf extract, an apios americana medikus tuber ethyl alcohol extract and apios americana medikus leaf polysaccharide. According to application of the apios americana medikus extract in weight reduction, a new resource is provided for development of natural weight reduction products in the fields of medicine, food science and the like. According to application, it is discovered for the firsttime that the apios americana medikus extract can obviously improve the immunity and inhibit the functions of cellular immunity, humoral immunity and innate immunity of a mouse, is wide in application range and has an obvious effect and good development prospects. According to application, it is discovered for the first time that intervention of the apios americana medikus extract has an obviousanti-tumor effect.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the application of bean and taro extracts in the preparation of foods or medicines for weight loss, anti-tumor and immunity enhancement. Background technique [0002] Apios americana Medikus is a perennial leguminous plant (Papilionaceae subfamily) native to the eastern part of North America from Canada to the southern part of Florida. Its edible part is the underground tuber, and its protein content is higher than that of other plant tubers. It is a crop with both nutrition and economic value, so it is often used as a staple food by Indians. Bean taro has been successfully introduced in China since 2009, and has been gradually promoted and planted in Fuyang, Jinhua, Longyou, Wenzhou and other places. Studies have shown that different parts of taro (flowers, vines, leaves, tubers) are rich in free amino acids, soluble proteins, polysaccharides, saponins, flavonoids, isoflavones, vitamin ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P37/04A23L33/105
CPCA23V2002/00A61K36/48A61K2236/333A61K2236/39A61K2236/51A61K2236/55A23L33/105A23V2200/324A23V2250/21
Inventor 郑晓冬楚强俞露霜叶映凡宋东筱陈鹏华刘阳阳李永璐
Owner ZHEJIANG UNIV
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