Method for extracting cannabidiol

Abstract

The present invention provides a method for extracting cannabidiol, and belongs to the technical field of industrial extraction. The method comprises the following operation steps of drying the flowers and leaves of a mariguana plant, grinding and crushing, performing reverse extracting on the crushed coarse powder and a solvent in a reverse extracting device along the opposite directions, and enabling the solvent to extract the effective components of the coarse powder out of an extracting solution; performing pressure-relief heating on the extracting solution, and volatilizing the excessiveethanol in the extracting solution, so as to obtain a concentrated solution of cannabidiol; adding purified water into the concentrated solution of cannabidiol, diluting, eluting by a chromatography column in a gradient way, and collecting a target eluting solution; combining the target eluting solution, and performing pressure-relief concentrating at the temperature of 50 to 70 DEG C, so as to obtain a secondary concentrated solution of cannabidiol; adding 90%w / w ethanol over-saturated solution into the secondary concentrated solution of cannabidiol, obtaining a crystallized product, washingby the purified water, and drying, so as to obtain a cannabidiol product. The method has the advantages that the method can be applied to large-scale continuous production; the working is continuous without interruption; the output is high; the energy source is saved; the safety and reliability are realized.

Description

technical field [0001] The invention relates to the technical field of industrial extraction, in particular to a method for extracting cannabidiol. Background technique [0002] Cannabis (Cannabis sativa Linn.) is an annual early plant with important medicinal value, belonging to Magnoliopsida, Urticales, Cannabinaceae, Cannabis, also known as hemp, hemp , hemp, mountain silk hemp, jute and industrial hemp. Cannabis flowers and leaves to be bloomed contain rich physiologically active components including cannabinoids and non-cannabinoids, among which the number of cannabinoids and physiologically active components are relatively large. At present, there are more than 80 kinds of cannabinoids (CBs) isolated from cannabis, mainly including cannabidiol (CBD), tetrahydrocannabinol (THC), cannabinol (CBN) and cannabinoids. Cannabichromene (CBC), etc., among which cannabidiol (CBD) and tetrahydrocannabinol (THC) have the highest content, which are typical representatives of cann...

AI Technical Summary

Problems solved by technology

[0004] 1) Solvent extraction is the most used in the existing cannabidiol extraction process, one is to add a large amount of organic solvents with high solubility of cannabidiol, such as n-hexane, petroleum ether, dichloromethane, chloroform and methanol, etc., although The extraction rate of cannabidiol is improved, but the use of organic solvents will harm the environment, and the solvent residues in the final product cannot be removed, which also affects product safety; the other uses ethanol as the extractant, although it reduces the organic solvent Toxicity, but there is a problem of low extraction rate caused by low solubility of cannabidiol

[0005] 2) Supercritical CO 2 Fluid extraction technology has been applied in the extraction process of cannabidiol in recent years. Although supercritical extraction has the advantages of strong extraction capacity, high extraction rate, strong selectivity, and good product quality, it also has high cost, high energy consumption, and difficulty in industrialization. Disadvantages such as scale-up production

[0006] 3) Most of the existing production processes are mostly batch production, and it is difficult to achieve continuous production

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