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Gel product instant-dissolving block and preparation method thereof

A product, instant technology, applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc., can solve the problems of insoluble block glue products, etc., achieve special texture, meet packaging and Transportation needs, the effect of solid appearance

Active Publication Date: 2018-12-04
东阿阿胶保健品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problem that block-like glue products are not easy to dissolve, the present invention provides an instant block of glue-like products that can be quickly dissolved without adding chemical disintegration and co-solvent and its preparation method, which increases the carrying, taking and handling of glue-like products. Convenience

Method used

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  • Gel product instant-dissolving block and preparation method thereof
  • Gel product instant-dissolving block and preparation method thereof
  • Gel product instant-dissolving block and preparation method thereof

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preparation example Construction

[0031] In order to overcome the technical problems of poor solubility, inconvenient use, and a single way of taking the same product in traditional block-shaped gelatinous products, the present invention provides a preparation method for instant blocks of gelatinous products, which includes the following steps:

[0032] (1) The raw material glue is dissolved in water, and the glue is obtained after concentration;

[0033] (2) the glue solution is processed through vacuum belt drying to obtain a honeycomb-shaped colloid;

[0034] (3) pulverize the colloid, and sieve to obtain flake rubber powder with a particle size not less than 80 mesh;

[0035] (4) After the rubber powder is wetted with 85-95% alcohol, it is pressed with a compression ratio of 30%-60%, and the obtained pressed block is the instant block of the rubber product.

[0036] In the present invention, the raw material glue is the well-known medicinal and edible homologous glue or glue-like traditional Chinese medic...

Embodiment 1

[0051] (1) Add the donkey-hide gelatin raw material together with a certain amount of rock sugar and yellow rice wine into water of 5 times the total mass, heat and stir to dissolve completely. Concentrate the melted donkey-hide gelatin solution to a relative density of 1.16-1.19 (75°C);

[0052] (2) The concentrated donkey-hide gelatin liquid is dried by a vacuum belt drying process to obtain a coarse powder. The vacuum belt drying parameters are: feed temperature 67°C, feed speed 19L / h, crawler running speed 15cm / min; heating temperature of the first, second, third, fourth and fifth sections are 95±5°C respectively , 97±5℃, 97±5℃, 97±5℃, 25±5℃; cutter 25 seconds / time, vacuum degree 98KPa.

[0053] (3) Grinding with particle size control: the coarse powder obtained by drying is pulverized by a low-speed pulverizer at a frequency of 15 Hz using a sieve with an aperture of 2 to 3 mm. Then pass through a 30-mesh to 80-mesh vibrating sieve and sieve, and take the particles betw...

Embodiment 2

[0060] (1) Add the tortoise shell gum raw material and rock sugar to 3 times the amount of water, heat and stir to dissolve completely. Concentrate the melted glue to a relative density of 1.16-1.19 (75°C);

[0061] (2) The concentrated tortoise shell glue solution is dried by a vacuum belt drying process to obtain a coarse powder. Vacuum belt drying parameters are: feed temperature 62°C, feed speed 14L / h, crawler running speed 13cm / min; heating temperature of the first, second, third, fourth and fifth sections are respectively 95±5°C , 97±5℃, 97±5℃, 97±5℃, 25±5℃; cutter 19 seconds / time, vacuum degree 98KPa.

[0062] (3) Grinding with particle size control: use a low-speed pulverizer to pulverize the dried coarse powder with a 2-3mm aperture screen at a frequency of 13Hz, and then sieve through a 30-mesh-80-mesh vibrating sieve, and take a 30-mesh-80-mesh sieve The particles in between are tortoise shell glue powder, set aside.

[0063] (4) Spray evenly the alcohol with a v...

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Abstract

The invention relates to a gel product instant-dissolving novel dosage, and in particular relates to a gel product instant-dissolving block and a preparation method of the gel product instant-dissolving block. The preparation method comprises the following steps: adding water into a raw material so that the raw material is dissolved, and carrying out concentrating to obtain a gel solution; carrying out drying treatment on the gel solution, thus obtaining an irregular cellular gel body; grinding the gel body, and carrying out screening to obtain gel powder with the partical size not being smaller than 80 meshes; and wetting the gel powder by adopting 85-95 % alcohol, and carrying out compressing according to the compression ratio of 30%-60% for obtaining a block, wherein the obtained pressed block is the gel product instant-dissolving block. The gel product instant-dissolving block provided by the invention has the loose pore structure inside, has high superficial area / volume ratio, hasthe product density being 0.4-0.8 g / cm<3>, and can rapidly dissolve within 2min in hot water, in addition, the gel product instant-dissolving block is crisp in mouthfeel and can be directly orally administrated, and thus the convenient taking demand of consumers under different conditions can be satisfied.

Description

technical field [0001] The invention relates to a new instant dosage form of glue products, in particular to an instant block of glue products and a preparation method thereof. Background technique [0002] Glue refers to animal skin, bone, nail or horn, which is decocted with water, concentrated into a thick jelly, and made into a solid block oral preparation after drying. The preparation form has a long history. The traditional glue is in the form of a hard block. When taking it, it needs to be crushed and added to the rice wine for more than 24 hours, or it needs to be powdered with a powder machine and then swallowed. The processing time is long, or special crushing equipment is required, which is cumbersome and inconvenient. [0003] Compared with powder products, block products are small in size, easy to carry, and not easy to pour, no fine powder flying and residue in the bag, which has many advantages. However, the formability and instant solubility of block produc...

Claims

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Application Information

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IPC IPC(8): A61K9/00
CPCA61K9/0056A61K9/0095A61K35/32A61K35/36A61K35/586A61K9/2095A61K9/2063A61K47/46
Inventor 秦玉峰周祥山张淹孙阳恩金玉翠王春艳李丽张路于学龙
Owner 东阿阿胶保健品有限公司
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