Traditional Chinese medicine composition for treating piglet epidemic diarrhea
A technology of epidemic diarrhea and composition, applied in the field of veterinary traditional Chinese medicine, can solve the problems of ineffective control of virus transmission, lack of prevention and control methods for diseases, and inability of vaccines to effectively prevent piglet epidemic diarrhea, etc.
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Embodiment 1
[0024] Example 1, the preparation of the oral liquid of the traditional Chinese medicine composition: four kinds of medicinal materials were weighed according to the prescription, and the volatile oil of Shichangpu was extracted by distillation and refrigerated for later use; For 60 minutes each time, combine the filtrates, recover ethanol, concentrate under reduced pressure to a traditional Chinese medicine clear ointment with a density of 1.20-1.25 (60°C), conduct semi-finished product inspection, and refrigerate after passing the test. Add appropriate amount of solubilizer, emulsifier and appropriate amount of water for injection to the traditional Chinese medicine clear ointment, mix and then add Shichangpu volatile oil and mix well, add appropriate amount of preservative, dilute to 1g / ml with water for injection, and adjust the pH value to 5-7 Between, filter, pack, sterilize.
Embodiment 2
[0025] Example 2, the preparation of the granules of the traditional Chinese medicine composition: weigh four kinds of medicinal materials according to the prescription, extract the volatile oil of Shichangpu by distillation, and then use an appropriate amount of cyclodextrin to coat it and refrigerate it for later use; the remaining three medicinal materials are respectively used with 10, 8, 8 times 60% ethanol reflux extraction 3 times, 60 minutes each time, combine the filtrate, recover ethanol, concentrate under reduced pressure to a Chinese medicine clear ointment with a density of 1.20-1.25 (60°C), and add cyclodextrin inclusion to the traditional Chinese medicine clear ointment The volatile oil and appropriate amount of powdered sugar and dextrin are mixed, granulated, dried, granulated, and packed.
Embodiment 3
[0026] Embodiment 3: the quality standard and inspection method of this product granule:
[0027] Identification of Hypericum perforatum: Take an appropriate amount of this product and grind it finely, take about 1g of the powder, add 20ml of methanol, ultrasonicate for 15 minutes, filter, evaporate the filtrate to dryness, add 1ml of methanol to dissolve the residue, and use it as the test solution. Separately take Hypericum perforatum reference drug powder 0.2g, and prepare reference drug solution in the same way. According to the test of thin-layer chromatography (2010 edition of the Veterinary Drug Code Appendix 32), draw 10ul of each of the above two solutions, respectively spot on the same silica gel G thin-layer plate, and use toluene-ethyl acetate-formic acid (20:10:1) It is used as developing agent, developed, taken out, and inspected under ultraviolet light (365nm) immediately. In the chromatogram of the test product, at the position corresponding to the chromatogra...
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