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Drug for treating diabetics and preparation method and application thereof

A diabetes drug and diabetes technology, applied in the field of medicine, can solve the problems of western medicine and insulin with large toxic and side effects, diabetes can not meet people's expectations, hinder the application of traditional Chinese medicine for diabetes, etc., achieve good clinical efficacy, improve clinical symptoms and regulate lipid metabolism, Improve the effect of defense function

Inactive Publication Date: 2017-02-22
广西中医药大学第一附属医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, western medicine and insulin are mainly used in the treatment of diabetes. However, western medicine and insulin have large toxic and side effects and single curative effect. However, the influence of western medicine on metabolism and organ damage is still relatively large, and most of them have certain side effects, which partially limit their clinical application and make the control of diabetes unsatisfactory.
Traditional Chinese medicine has a long history of treating diabetes. Traditional Chinese medicine has the advantages of less toxic and side effects and less impact on organs. However, most of the traditional Chinese medicines for treating diabetes on the market are not very effective in clinical efficacy, which hinders the application of Chinese medicine in the treatment of diabetes.

Method used

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  • Drug for treating diabetics and preparation method and application thereof
  • Drug for treating diabetics and preparation method and application thereof
  • Drug for treating diabetics and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] In an embodiment of the present invention, a medicine for treating diabetes is composed of the following raw materials in parts by weight: 3 parts of montmorillonite, 15 parts of longan stalk, 11 parts of camphor fruit, and 1 part of rice lily.

[0025] Grind and crush the montmorillonite and camphor fruit, pass through a 120-mesh sieve, add 45% ethanol 5 times its mass, stir at 68°C for 20 minutes, and then ultrasonicate for 25 minutes, with ultrasonic power of 700W, 3000r / min After centrifugation, the supernatant was taken and vacuum-dried to obtain mixture A. Pulverize the longan, extract with water at a temperature of 81° C., separate the extract from the longan precipitate, and concentrate the extract to obtain the longan water extract. Pulverize the rice lily, pass through a 120-mesh sieve, add vinegar 1.7 times its mass, and stir until dry at a temperature of 75° C. to obtain the rice lily powder. Mix the mixture A, longan saccharine water extract and rice lily ...

Embodiment 2

[0027] In an embodiment of the present invention, a medicine for treating diabetes is composed of the following raw materials in parts by weight: 7 parts of montmorillonite, 23 parts of longan stalk, 19 parts of camphor fruit, and 5 parts of rice lily.

[0028] Grind and crush the montmorillonite and camphor fruit, pass through a 120-mesh sieve, add 45% ethanol 5 times its mass, stir at 68°C for 20 minutes, and then ultrasonicate for 25 minutes, with ultrasonic power of 700W, 3000r / min After centrifugation, the supernatant was taken and vacuum-dried to obtain mixture A. Pulverize the longan, extract with water at a temperature of 81° C., separate the extract from the longan precipitate, and concentrate the extract to obtain the longan water extract. Pulverize rice lily, pass through a 120-mesh sieve, add vinegar 1.7 times its mass, and stir until dry at a temperature of 77°C to obtain rice lily powder. Mix the mixture A, longan saccharine water extract and rice lily powder, a...

Embodiment 3

[0030] In an embodiment of the present invention, a medicine for treating diabetes is composed of the following raw materials in parts by weight: 4 parts of montmorillonite, 17 parts of longan stalk, 13 parts of camphor fruit, and 2 parts of rice lily.

[0031] Grind and crush the montmorillonite and camphor fruit, pass through a 120-mesh sieve, add 45% ethanol 5 times its mass, stir at 68°C for 20 minutes, and then ultrasonicate for 25 minutes, with ultrasonic power of 700W, 3000r / min After centrifugation, the supernatant was taken and vacuum-dried to obtain mixture A. Pulverize the longan, extract with water at a temperature of 81° C., separate the extract from the longan precipitate, and concentrate the extract to obtain the longan water extract. Pulverize the rice lily, pass through a 120-mesh sieve, add vinegar 1.7 times its mass, and stir until dry at a temperature of 76° C. to obtain the rice lily powder. Mix the mixture A, longan saccharine water extract and rice lily...

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Abstract

The invention discloses a drug for treating diabetics and a preparation method and application thereof; the drug is prepared from, by weight, 3-7 parts of montmorillonite, 15-23 parts of Fructificatio Hexagoniae Apiariae, 11-19 parts of fruit of Cinnamomum bodinieri, and 1-5 parts of bulb of Fritillaria davidii; the preparation method comprises: grinding and crushing montmorillonite and fruit of Cinnamomum bodinieri, adding 45% ethanol, heating and stirring, ultrasonically treating, centrifuging, and drying in vacuum to obtain mixture A; crushing Fructificatio Hexagoniae Apiariae, extracting with water, and concentrating to obtain aqueous extract of Fructificatio Hexagoniae Apiariae; crushing bulb of Fritillaria davidii, adding edible vinegar, stirring to dryness to obtain bulb powder of Fritillaria davidii; mixing the above materials, microwave-treating, drying, and granulating. The drug has significant hyperglycemic effect, can improve heavy-headedness, weak, numbness and pain due to diabetics and various complications, has no toxic and side effects, can repair injured pancreas, liver, and kidney tissues, has good and quick action for treating diabetics, and is suitable for wide application.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a medicine for treating diabetes and its preparation method and application. Background technique [0002] Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia due to defects in insulin secretion and / or insulin action. Sustained high blood sugar and long-term metabolic disorders can lead to damage, dysfunction and failure of tissues and organs throughout the body, especially the eyes, kidneys, cardiovascular and nervous systems. Severe cases can cause acute complications such as dehydration, electrolyte disturbance and acid-base imbalance, ketoacidosis and hyperosmolar coma. [0003] At present, western medicine and insulin are mainly used in the treatment of diabetes. However, western medicine and insulin have large toxic and side effects and single curative effect. However, the impact of Western medicine on metabolism and organ damage is still re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61P3/10A61K33/06
CPCA61K33/06A61K9/1605A61K36/54A61K36/77A61K36/8966A61K2236/331A61K2236/333A61K2236/51A61K2236/53A61K2300/00
Inventor 唐宏亮庞军林静王开龙
Owner 广西中医药大学第一附属医院
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