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Medicine for preventing and treating animal foot-and-mouth disease

A technology of foot-and-mouth disease and foot-and-mouth disease virus, which is applied in the field of medicine, can solve problems such as foot-and-mouth disease that have never been seen, and achieve the effects of improving immunity, relieving gastrointestinal hemorrhagic inflammation, and inhibiting damage

Inactive Publication Date: 2016-10-05
耿福能
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In the field of veterinary medicine, there have been no relevant reports on the treatment of foot-and-mouth disease by Periplaneta americana or its extracts

Method used

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  • Medicine for preventing and treating animal foot-and-mouth disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1 Preparation method of Periplaneta americana extract

[0026] Coarsely crush 1000kg of dried Periplaneta americana, add 6 times the amount of 75% ethanol, soak for 1.5 hours, and extract twice at a temperature of 75°C for 8 hours for the first time; add 4 times the amount of ethanol for the second time, extract for 6 hours and combine Secondary extract, filter, collect dregs, when the filtrate is concentrated to a clear ointment with a relative density of 1.02-1.15 (65°C), add water, keep stirring at 75°C for 30 minutes, let stand for 10 hours, discard the upper layer of grease, and the lower layer Filter the liquid medicine, recover ethanol from the filtrate, concentrate under reduced pressure to a liquid medicine with a relative density of 1.10-1.20 (65°C), add 70ml of glycerin for every 1000ml, stir well, filter, boil the filtrate for 30 minutes, and then pack it into a spray bottle , 150ml per bottle, and then sterilized at 125°C under a pressure of 0.1...

Embodiment 2

[0028] Example 2 Pig Foot and Mouth Disease

[0029] Diseased pigs: 100 sick piglets weighing 30-40 kg, of which 60 had just blisters on the nose, nose and hooves (the blisters were not broken); 15 had blisters around the nose, nose and hooves that had ruptured and bled; In addition to blisters on the mouth, nose and hooves of the head, blisters and rotten spots appeared on the esophagus and gastric mucosa, and 5 heads had gastrointestinal bleeding and other inflammations.

[0030] Get the Periplaneta americana extract prepared in Example 1 and spray it on the hooves and snouts of sick pigs, each spraying 10ml on each affected part, 4 times a day. Except for the sick pigs that just had blisters that only needed external spraying, the rest of the sick pigs needed to be fed with 20ml each time, 3 times a day. 1-2 weeks of serious illness is a course of treatment.

[0031] In the process of treating porcine foot-and-mouth disease with the extract of Periplaneta americana, i...

Embodiment 3

[0032] Example 3 Foot and Mouth Disease

[0033] Sick cows: 60 sick calves aged 4-5 months, of which 25 just had blisters on their nose, nose and hooves (the blisters were not broken); In addition to the blisters on the mouth, nose and hooves, 12 of them had blisters and rotten spots on the esophagus and gastric mucosa, and 1 had inflammation such as gastrointestinal bleeding.

[0034] Get the Periplaneta americana extract that embodiment 1 prepares, spray on the hoof and snout place of diseased cow, every affected part sprays 10ml every time, a day 4 times. Except for the 5 cows that had just developed blisters that only needed external spraying treatment, the other 5 diseased cows needed to be treated by gavage, each with 20ml each time, 3 times a day. 1-2 weeks of serious illness is a course of treatment.

[0035] In the process of using the Periplaneta americana extract to treat bovine foot-and-mouth disease, the medicinal residue powder prepared in Example 1 can be...

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PUM

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Abstract

The invention discloses a medicine for preventing and treating animal foot-and-mouth disease. The medicine is obvious in effect, free of toxic and side effects and medicine resistance, economical and effective, is a periplaneta-americana extract, and has the obvious treating effect on an application to treating animal foot-and-mouth disease, and the total effective rate can be 90% or above. After medicine dregs of extracted periplaneta americana are prepared into medicine dreg powder, the medicine dreg powder can be in cooperation with feed to treat foot-and-mouth-disease animals in an auxiliary mode, medicine dregs of periplaneta americana are fully used, and the objective economic value is achieved.

Description

technical field [0001] The invention belongs to the field of medicine, in particular to a medicine for preventing and treating animal foot-and-mouth disease. Background technique [0002] Foot-and-mouth disease, abbreviated as FDM in English, is an acute, febrile, highly contagious infectious disease common to pigs, cattle, sheep and other domestic and wild cloven-hoofed animals, with more than 70 susceptible animals. The clinical feature is a vesicular eruption on the oral mucosa, hooves, and breast skin. The disease has many transmission routes and fast speed, and has repeatedly broken out in the world, causing huge political and economic losses. In view of this, the World Organization for Animal Health (OIE) listed it as the first class A infectious disease. At present, FMD is prevalent in two-thirds of OIE member countries, threatening the safety of livestock and the trade of livestock products in non-FMD countries and regions. [0003] Cloven-hoofed animals infected ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/64A61P31/14A61P1/00A61P7/04
CPCY02A40/70
Inventor 耿福能
Owner 耿福能
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