Gelatin empty capsule and preparation method thereof

A hollow capsule and gelatin technology, which is applied in the directions of capsule delivery, pharmaceutical formulations, and medical preparations with inactive ingredients, etc., can solve the problems of being susceptible to moisture, slow dissolving, and difficult to enter.

Inactive Publication Date: 2016-08-03
夏放军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although hollow capsules have solved the problem of being difficult to swallow and have truly realized that good medicine is no longer bitter, the current hollow capsules are prone to moisture and dissolve slowly

Method used

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  • Gelatin empty capsule and preparation method thereof

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Effect test

Embodiment 1

[0022] A method for preparing a gelatin hollow capsule, comprising the following raw materials in parts by weight: 37 parts of medicinal gelatin, 8 parts of zein, 4 parts of cocoa pigment, 5 parts of blueberry anthocyanin, and 1 part of poloxamer , 1 part of hydroxypropyl methylcellulose, 2 parts of microcrystalline cellulose, 5 parts of carrageenan, 10 parts of peach gum, 5 parts of agar powder, 7 parts of kudzu starch, 18 parts of hydrogenated soybean oil, 17 parts of beeswax, maltol 2 parts, 2 parts calcium carbonate and 1 part sodium bicarbonate.

[0023] A kind of preparation method of gelatin hollow capsule comprises the following steps:

[0024] 1) Pour 37 parts of medicinal gelatin, 5 parts of carrageenan, 10 parts of peach gum, 5 parts of agar powder, 17 parts of beeswax and 18 parts of hydrogenated soybean oil into a container, and then heat it at 85°C. Stir continuously until the material is completely dissolved to obtain a viscous liquid, set aside;

[0025] 2) P...

Embodiment 2

[0033] A gelatin hollow capsule and a preparation method thereof, comprising the following raw materials in parts by weight: 35 parts of medicinal gelatin, 10 parts of zein, 6 parts of cocoa pigment, 7 parts of blueberry anthocyanin, and 3 parts of poloxamer 3 parts of hydroxypropyl methylcellulose, 4 parts of microcrystalline cellulose, 7 parts of carrageenan, 12 parts of peach gum, 7 parts of agar powder, 9 parts of kudzu starch, 20 parts of hydrogenated soybean oil, 19 parts of beeswax, malt 4 parts of phenol, 4 parts of calcium carbonate and 3 parts of sodium bicarbonate.

[0034] A preparation method for gelatin hollow capsules, comprising the following steps:

[0035] 1) Pour 35 parts of medicinal gelatin, 7 parts of carrageenan, 12 parts of peach gum, 7 parts of agar powder, 19 parts of beeswax and 20 parts of hydrogenated soybean oil into a container, and then heat it at 85°C. Stir continuously until the material is completely dissolved to obtain a viscous liquid, set...

Embodiment 3

[0044] A gelatin hollow capsule and a preparation method thereof, comprising the following raw materials in parts by weight: 36 parts of medicinal gelatin, 9 parts of zein, 5 parts of cocoa pigment, 6 parts of blueberry anthocyanin, and 2 parts of poloxamer 2 parts of hydroxypropyl methylcellulose, 3 parts of microcrystalline cellulose, 6 parts of carrageenan, 11 parts of peach gum, 6 parts of agar powder, 8 parts of kudzu starch, 19 parts of hydrogenated soybean oil, 18 parts of beeswax, malt 3 parts of phenol, 3 parts of calcium carbonate and 2 parts of sodium bicarbonate.

[0045] A preparation method for gelatin hollow capsules, comprising the following steps:

[0046] 1) Pour 36 parts of medicinal gelatin, 6 parts of carrageenan, 11 parts of peach gum, 6 parts of agar powder, 18 parts of beeswax and 19 parts of hydrogenated soybean oil into a container, and then heat it at 85°C. Stir continuously until the material is completely dissolved to obtain a viscous liquid, set as...

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Abstract

The invention discloses a gelatin empty capsule and a preparation method thereof. The gelatin empty capsule is prepared from, by weight, 35-37 parts of pharmaceutical gelatin, 8-10 parts of zein, 4-6 parts of cocoa pigments, 5-7 parts of blueberry anthocyanins, 1-3 parts of poloxamer, 1-3 parts of hydroxypropyl methyl cellulose, 2-4 parts of microcrystalline cellulose, 5-7 parts of carrageenan, 10-12 parts of peach gum, 5-7 parts of agar powder, 7-9 parts of kudzu starch, 18-20 parts of hydrogenated soybean oil, 17-19 parts of beewax, 2-4 parts of maltol, 2-4 parts of calcium carbonate and 1-3 parts of sodium bicarbonate. The gelatin empty capsule is high in dissolution rate and not prone to be affected with damp.

Description

technical field [0001] The invention relates to a gelatin hollow capsule and a preparation method thereof. Background technique [0002] The hollow capsule is composed of a capsule shell with a cap and a body refined from medicinal gelatin and auxiliary materials. Mainly used to contain solid medicine. For example, self-made powders, health care products, medicines, etc., have solved the problem of ingestion for users, and truly realized that good medicine is no longer bitter. Hollow capsules are becoming more and more popular. First of all, capsules are slender in shape and easy to swallow, making them the most popular dosage form for consumers. In addition, capsules can effectively cover up the unpleasant taste and smell of the contents. Capsules come in a variety of sizes and can be printed with text, logos and graphics for a unique custom look. [0003] Capsules can hold a variety of powders, liquids, semi-solids, and tablets. In addition, the capsules have good bioa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K47/46A61K47/44A61K47/42A61K47/38A61K47/36A61K47/02
CPCA61K9/4825A61K47/02A61K47/36A61K47/38A61K47/42A61K47/44A61K47/46
Inventor 夏放军
Owner 夏放军
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