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A traditional Chinese medicine composition for treating and/or preventing oral diseases and its preparation method

A technique for oral diseases and compositions, applied in the field of traditional Chinese medicine compositions, which can solve the problems of low local drug concentration, inconvenient use, and drug resistance, and achieve the effects of good solubility, health promotion, and alleviation of related symptoms

Active Publication Date: 2018-01-19
BEIJING TONGRENTANG MAIERHAI BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although basic periodontal treatment is effective in removing plaque and controlling inflammation, it is difficult to control plaque at an ideal level for a long time
Long-term use of antibiotics throughout the body may lead to adverse consequences such as bacterial imbalance and drug resistance, while the local concentration of the drug is relatively low
Although topical periodontal medication can avoid the possible adverse consequences of systemic medication, it also has disadvantages such as inconvenient use, multiple side effects, and drug resistance.
In addition, most of the various periodontal topical dosage forms at present are mainly antibacterial and bactericidal preparations, or some biofilm preparations can only promote the regeneration of gingival tissue

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] The preparation method of Panax notoginseng powder is as follows: taking an appropriate amount of Panax notoginseng, washing and drying, grinding the Panax notoginseng pieces into fine powder with an ultra-fine pulverizer, passing through a 200-mesh sieve, and preparing for use.

[0043] The preparation method of Salvia miltiorrhiza extract is as follows: take an appropriate amount of Salvia miltiorrhiza, soak it for 0.5-1.0 h, decoct and extract twice at 90-100°C, add 10-12 times the amount of water for the first time, extract for 1.0-1.5 h, and the second time Add 5-8 times the amount of water, extract for 0.5-1.0 h, filter each time, combine the filtrates, concentrate the volume of the filtrate to 2-3 times g / ml of the weight of Salvia miltiorrhiza, filter, and dry to obtain powder for later use.

[0044] The preparation method of wild chrysanthemum flower extract is as follows: take an appropriate amount of wild chrysanthemum flower, soak it for 0.5-1.0 h, heat and d...

Embodiment 2

[0054] The preparation methods of Panax notoginseng powder, Salvia miltiorrhiza extract, and wild chrysanthemum extract are the same as those in Example 1.

[0055] In parts by weight, the following components were prepared: 0.03 part of Panax notoginseng powder, 0.08 part of Salvia miltiorrhiza extract, 0.06 part of wild chrysanthemum extract, 50 parts of sorbitol, 2.0 parts of polyethylene glycol-4000, 25 parts of water, 0.3 part of saccharin, 0.3 parts of sodium benzoate, 10 parts of glycerin, 0.5 parts of hydroxypropyl guar gum, 0.5 parts of carrageenan extract, 0.3 parts of cellulose gum, 20 parts of hydrated silica, 3.0 parts of sodium lauryl sulfate, 1.5 parts of titanium dioxide , flavor 2.0 copies.

[0056] The preparation method of toothpaste is the same as that in Example 1.

Embodiment 3

[0058] The preparation methods of Panax notoginseng powder, Salvia miltiorrhiza extract, and wild chrysanthemum extract are the same as those in Example 1.

[0059] In parts by weight, the following components were prepared: 0.05 part of Panax notoginseng powder, 0.1 part of Salvia miltiorrhiza extract, 0.08 part of wild chrysanthemum extract, 45 parts of sorbitol, 1.5 part of polyethylene glycol-4000, 22 parts of water, 0.25 part of saccharin, 0.25 parts of sodium benzoate, 7 parts of glycerin, 0.45 parts of hydroxypropyl guar gum, 0.4 parts of carrageenan extract, 0.25 parts of cellulose gum, 17 parts of hydrated silica, 2.5 parts of sodium lauryl sulfate, 1.2 parts of titanium dioxide , 1.5 copies of essence.

[0060] The preparation method of toothpaste is the same as that in Example 1.

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition for treating and / or preventing oral diseases. The traditional Chinese medicine composition is prepared from pseudo-ginseng powder, radix salviae milliorrhizae extract and wild chrysanthemum extract. The invention further provides toothpaste capable of treating and / or preventing gingivitis. The toothpaste contains the traditional Chinese medicine composition and auxiliary materials. The ointment is moderate in thickness, rich and fine in foam and high in solubility; due to the fact that natural plant extract is added, the toothpaste is mild, high in safety performance, remarkable in effect and capable of reducing the number of oral cavity germs and regulating the environment of the oil environment.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating and / or preventing oral diseases, in particular to a traditional Chinese medicine toothpaste for preventing and treating gingivitis and a preparation method thereof. Background technique [0002] In medicine, the soft tissue surrounding and covering the teeth is called gingiva, and the acute and chronic inflammation that occurs in the gingival tissue is called gingivitis. It is manifested as gingival bleeding, redness, swelling and pain, and continues to develop and invade hard tissues, resulting in periodontitis, including inflammation of gingival tissue and the performance of systemic diseases in the gingiva. [0003] Most cases of gingivitis are caused by local factors, mainly caused by plaque, calculus or food impaction on the neck of the tooth, causing gingival bleeding, edema, gingivitis and periodontitis. The gingival sulcus endothelial tissue is congested, and the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/537A61K8/9789A61Q11/00A61P1/02
CPCA61K8/97A61K36/00A61K36/258A61K36/287A61K36/537A61K2800/34A61Q11/00A61K2300/00
Inventor 尹鹭王海平杜喜平
Owner BEIJING TONGRENTANG MAIERHAI BIOTECHNOLOGY CO LTD
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