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Traditional Chinese medicine composition treating diabetic nephropathy and preparing method thereof

A technique for diabetic nephropathy and its composition, which is applied in the field of traditional Chinese medicine composition for treating diabetic nephropathy and its preparation, can solve the problems that the effect is not very obvious, and achieve the effects of protecting kidney function, taking conveniently, and having good curative effect

Inactive Publication Date: 2015-10-21
QINGDAO LANSHENGYANG PHARMA & BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Chinese medicine composition has the effect of reducing the excretion of proteinuria and prolonging the progress of diabetic nephropathy, but the effect of the Chinese medicine composition on lowering blood sugar, tonifying the kidney and invigorating the spleen is not very significant

Method used

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  • Traditional Chinese medicine composition treating diabetic nephropathy and preparing method thereof
  • Traditional Chinese medicine composition treating diabetic nephropathy and preparing method thereof
  • Traditional Chinese medicine composition treating diabetic nephropathy and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The pharmaceutical composition of Example 1 of the present invention includes the following preparation raw materials in parts by weight: 5 parts of total flavonoids of Moringa oleifera leaves, 1 part of stilbene glycosides, 1 part of ginsenoside Rb1, 1 part of ginsenoside Rg1, 1 part of ginsenoside Rd, 1 part Ginsenoside Re, 1 part Ginkgolide, 1 part Kaempferol, and 1 part Quercetin.

[0032] The preparation method is as follows:

[0033] (1) Preparation of total flavonoids from Moringa oleifera leaves:

[0034] A: take Moringa leaf, dry, pulverize, cross 45 mesh sieves, obtain Moringa leaf powder;

[0035] B: Take the Moringa oleifera leaf powder obtained in step A, add petroleum ether, reflux and degrease 3 times at 68° C. for 6 hours each time, filter, remove the filtrate, and dry the filter residue to obtain a dry filter residue;

[0036] C: Add 70% ethanol to the dried filter residue obtained in step B, process it at a microwave power of 600W for 7 minutes, extrac...

Embodiment 2

[0040] The pharmaceutical composition of Example 2 of the present invention includes the following preparation raw materials in parts by weight: 30 parts of total flavonoids of Moringa oleifera leaves, 18 parts of stilbene glycosides, 10 parts of ginsenoside Rb1, 10 parts of ginsenoside Rg1, 2 parts of ginsenoside Rd, 4 parts Ginsenoside Re, 4 parts Ginkgolide, 2 parts Kaempferol and 2 parts Quercetin.

[0041] The preparation method is the same as in Example 1.

Embodiment 3

[0043] The pharmaceutical composition of Example 3 of the present invention includes the following preparation raw materials in parts by weight: 20 parts of total flavonoids of Moringa oleifera leaves, 10 parts of stilbene glycosides, 5 parts of ginsenoside Rb1, 5 parts of ginsenoside Rg1, 1.5 parts of ginsenoside Rd, 2 parts ginsenoside Re, 2 parts ginkgolide, 1.5 parts kaempferol and 1.5 parts quercetin.

[0044] The preparation method is the same as in Example 1.

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Abstract

The invention belongs to the technical field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition treating diabetic nephropathy and a preparing method thereof. The traditional Chinese medicine composition comprises total flavones of moringa oleifera leaf, stibene glucoside, ginsenoside Rb 1, ginsenoside Rg1, ginsenoside Rd, ginsenoside Re, bilobalide, kaempferol and quercetin. The medicine components are reasonable, the synergism effect is high, the traditional Chinese medicine composition serves as the medicine compatibility for treating the diabetic nephropathy, and the clinic verifies that very obvious effects are achieved.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating diabetic nephropathy and a preparation method thereof. Background technique [0002] Diabetic nephropathy is one of the common complications of diabetes, which is a metabolic disease characterized by hyperglycemia. Hyperglycemia is caused by defective insulin secretion or impaired biological action, or both. The long-term existence of diabetes complicated by high blood sugar can easily lead to chronic damage and dysfunction of various tissues, especially the eyes, kidneys, heart, blood vessels, and nerves. Traditional Chinese medicine believes that deficiency of both qi and yin and blood stasis is the main clinical syndrome of diabetic nephropathy. [0003] At present, drugs for the treatment of diabetes are divided into three categories: 1. Pure western medicines, which are represented by...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P3/10A61P13/12A61K31/352A61K31/704
CPCA61K31/352A61K31/365A61K31/7034A61K31/704A61K36/185A61K2236/333A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 刘春同
Owner QINGDAO LANSHENGYANG PHARMA & BIOTECH CO LTD
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