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Preparation of Chinese medicine for venous thrombosis after joint replacement and method for preparing same

A technology for traditional Chinese medicine preparations and venous thrombosis, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, medical raw materials derived from arthropods, etc.

Inactive Publication Date: 2015-09-09
孙着叶
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because these major orthopedic operations sometimes cause damage to the vein wall of the patient, the venous blood flow stagnates slowly during the early postoperative bed rest period, and the blood is in a hypercoagulable state. If effective preventive measures are not taken at this time, venous thrombosis will easily occur
[0003] At present, for patients with postoperative deep vein thrombosis, thrombolytic therapy such as streptokinase and urokinase, or anticoagulant therapy such as heparin are generally used, and severe cases may even undergo surgery again. Thrombolytic therapy and anticoagulant therapy are likely to cause systemic Thrombolytic effect, and lead to bleeding, and may cause fever, rash, asthma and other complications; surgical treatment is undoubtedly a serious injury to the patient's body, and there is a certain risk, the treatment course is long, the cost is high, the patient It is not easy to accept, it is easy to cause delays in treatment, cause irreversible damage to the patient's body, and bring heavy mental and economic burdens to relatives and families

Method used

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  • Preparation of Chinese medicine for venous thrombosis after joint replacement and method for preparing same
  • Preparation of Chinese medicine for venous thrombosis after joint replacement and method for preparing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Example 1: 30 parts of Radix Astragali, 15 parts of Chuanxiong, 24 parts of Salvia, 12 parts of Aconite, 15 parts of Rhizoma Cyperi, 20 parts of Corydalis Corydalis, 18 parts of Achyranthes Radix, 15 parts of Radix Paeoniae Alba, 15 parts of Guizhi, 20 parts of Clematis , 9 parts of safflower, 24 parts of Caulis Spatholobus, 18 parts of Notopterygium, 18 parts of Du Huo, 9 parts of leech, 12 parts of wood beetle, 20 parts of Liu Jinu, 6 parts of frankincense, 6 parts of myrrh, 2 parts of horsefly, three 12 parts of ribs, 12 parts of curcuma.

Embodiment 2

[0041] Example 2: 31 parts of Radix Astragali, 16 parts of Rhizoma Chuanxiong, 25 parts of Salvia Miltiorrhiza, 12 parts of Aconite, 15 parts of Rhizoma Cyperi, 21 parts of Corydalis Corydalis, 19 parts of Achyranthes Radix, 16 parts of Radix Paeoniae Alba, 15 parts of Guizhi, 21 parts of Clematis , 10 parts of safflower, 23 parts of Caulis Spatholobus, 18 parts of Notopterygium, 18 parts of Du Huo, 9 parts of leech, 12 parts of ground beetle, 21 parts of Liu Jinu, 7 parts of frankincense, 7 parts of myrrh, 3 parts of horsefly, three 13 parts of ribs, 11 parts of curcuma.

Embodiment 3

[0042] Example 3: 32 parts of Radix Astragali, 16 parts of Chuanxiong, 23 parts of Salvia, 12 parts of Aconite, 15 parts of Rhizoma Cyperi, 21 parts of Corydalis Corydalis, 19 parts of Achyranthes Radix, 15 parts of Radix Paeoniae Alba, 15 parts of Guizhi, 20 parts of Clematis , 10 parts of safflower, 23 parts of Caulis Spatholobus, 18 parts of Notopterygium, 18 parts of Du Huo, 9 parts of leech, 12 parts of ground beetle, 21 parts of Liu Jinu, 6 parts of frankincense, 7 parts of myrrh, 2 parts of horsefly, three Rib 11 parts, Curcuma 12 parts.

[0043] Below is the clinical statistical data of patient using medicine of the present invention:

[0044] 1. General Information

[0045] From November 2011 to October 2013, 360 patients with deep vein thrombosis after joint replacement. The patients were randomly divided into the observation group and the control group, including 187 males and 173 females, with a male-to-female ratio of 1.1:1. The basic data of the two groups, suc...

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Abstract

The invention discloses a preparation of Chinese medicine for venous thrombosis after joint replacement. The preparation comprises the raw materials of Radix Astragali, Ligusticum wallichii, red sage root, Aconitum carmichaelii, Cyperus Rotundus L, corydalis tuber, cyathula root, white peony root, cassia twig, clematis root, safflower, spatholobus stem, notopterygium root, levisticum, leech, ground beetle, Artemisia anomala, frankincense, myrrh, gadfly, sparganium and curcuma rhizome and belongs to the invention field of traditional Chinese medicine. According to different characteristics of each Chinese medicament in the above preparation, after the raw materials are washed, cut into blocks and pre-treated, the raw materials are compounded in proportion and prepared through a special means to prepare the above preparation. The obtained preparation has the advantages of promoting circulation, removing stasis, extinguishing embolism and relaxing veins. The composition of the preparation and the method for preparing the preparation are unique. It has been verified by clinical experiments that, the preparation is obvious in treatment effect, short in treatment period, low in price, free of any adverse reaction or toxic / side effect, and broad in market application prospect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for venous thrombosis after joint replacement, and also relates to a preparation method of the traditional Chinese medicine preparation. Background technique [0002] Deep vein thrombosis (DVT) is prone to occur after major orthopedic surgery. Patients may have clinical symptoms such as leg swelling and pain. About 50%-80% of patients do not have any symptoms, but they may be complicated by long-term deep venous insufficiency of lower extremities and often Swollen legs or varicose veins can be complicated by pulmonary embolism (PE) in a small number of patients and lead to death, which is extremely harmful. It is primarily intended for patients who are about to undergo or have undergone total hip replacement, total knee replacement and hip fracture surgery. Because these major orthopedic operations sometimes cause damage to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P7/02A61K35/62A61K35/64
Inventor 孙著叶王光宇迟洪玲
Owner 孙着叶
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