Compounded traditional Chinese medicinal rana chensinensis extract preparation and application thereof in preparation of medicine and cosmetic for treating and preventing acnes

A compound preparation and traditional Chinese medicine technology, which is applied in the field of extracting traditional Chinese medicine compound preparations from forest frogs to prepare medicines and cosmetics for treating acne. It can solve problems that affect work and social activities, affect beauty, and mental burden of patients, and achieve fast healing and sterilization speed. Fast, easy-to-use effects

Inactive Publication Date: 2014-12-03
JILIN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The disease is lingering and difficult to heal and leaves scars, which not only affects the ap...

Method used

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  • Compounded traditional Chinese medicinal rana chensinensis extract preparation and application thereof in preparation of medicine and cosmetic for treating and preventing acnes
  • Compounded traditional Chinese medicinal rana chensinensis extract preparation and application thereof in preparation of medicine and cosmetic for treating and preventing acnes
  • Compounded traditional Chinese medicinal rana chensinensis extract preparation and application thereof in preparation of medicine and cosmetic for treating and preventing acnes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Example 1 Preparation of Rana Rana Extract Compound Chinese Medicine Preparation

[0067] (1) Preparation of Rana extract mixture

[0068] After removing impurities and dust, 54g of dried wood frog (dried wood frog is the dry body of wood frog for degreasing and removing eggs) is crushed through 20 mesh, 40 mesh, and 80 mesh respectively, so that the particle size of the dried wood frog is below 500 μm, according to Add the compound enzyme hydrolyzate at the ratio of 1g:8mL, the compound enzyme hydrolyzate contains papain 3wt%, trypsin 2wt%, flavor protease 1wt%, enzymolysis temperature is 55℃, enzymolysis time is 1h, enzymolysis pH is 7.2 , then 90°C, 10min to inactivate the enzyme, the mixture was centrifuged at a temperature of 25°C, the centrifugation time was 2min, and the centrifugation speed was 3500rpm, and the supernatant of 30% of the total volume of the mixed solution after centrifugation was taken, and the dried Rana rha The short peptide collagen contained...

Embodiment 2

[0078] The preparation of the compound ointment of embodiment two wood frogs extracting traditional Chinese medicine

[0079] Prescription composition (by weight): 54 parts of dried forest frog, 27 parts of gray sage, 1 part of Galla chinensis, 2 parts of Sophora flavescens, 1 part of purslane, 1 part of Cnidium oleracea, 1 part of Cortex Phellodendri, 1 part of mint leaf, notopterygium 2 parts, 1 part of Fangji, 1 part of Cangzhu, 2 parts of Baizhenpi, 2 parts of Huhuanglian, 1 part of Kochia, 2 parts of Baibu, 1 part of safflower, 1 part of Huoxiang, 1 part of Guizhi, 3 parts of honeysuckle Achyranthes knuckle 1 part, iron holly 1 part, paraffin wax 8 parts, liquid paraffin wax 6 parts, white vaseline 8 parts, glyceryl monostearate 3 parts, spar 402 parts, emulsifier OP3 parts, p-hydroxybenzoic acid ethyl 1 part of ester, 1 part of borneol.

[0080] Preparation:

[0081] (1) Preparation of compound preparation of Chinese medicine extracted from forest frog

[0082] Take b...

Embodiment 3

[0085] The preparation of embodiment three forest frogs extracting traditional Chinese medicine compound emulsion

[0086] Prescription composition (by weight): 54 parts of dried forest frog, 27 parts of gray sage, 1 part of Galla chinensis, 2 parts of Sophora flavescens, 1 part of purslane, 1 part of Cnidium oleracea, 1 part of Cortex Phellodendri, 1 part of mint leaf, notopterygium 2 parts, 1 part of Fangji, 1 part of Cangzhu, 2 parts of Baizhenpi, 2 parts of Huhuanglian, 1 part of Kochia, 2 parts of Baibu, 1 part of safflower, 1 part of Huoxiang, 1 part of Guizhi, 3 parts of honeysuckle 1 part of Achyranthes knuckles, 1 part of iron holly, 4 parts of stearic acid, 2 parts of stearyl alcohol, 3 parts of cetyl alcohol, 3 parts of white oil, 0.5 parts of Twenn-600, 1 part of lanolin, 0.5 parts of olive oil, 6 parts of glycerin, 0.3 part of triethanolamine, 0.1 part of jasmine essence, 0.05 part of Bropol, 0.05 part of propylparaben, and 70 parts of ultrapure water.

[0087] P...

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Abstract

The invention relates to a compounded traditional Chinese medicinal rana chensinensis extract preparation and an application thereof in preparation of a medicine and a cosmetic for treating and preventing acnes, and belongs to the technical field of traditional Chinese medicine preparations. A preparation method of the preparation comprises the following steps: removing impurities and dust from dried rana chensinensis and smashing, then adding a compound enzyme hydrolysate and centrifuging to obtain a supernate at an upper layer; grinding the rest of mixtures, then shearing and carrying out spray drying to form powder, adding the supper micropowder into an acetic acid and carrying out ultrasonic treatment, then filtering the micropowder with a gauze and centrifuging to obtain a supernate, and carrying out reduced pressure concentration on the supernate so as to obtain a mixture of polysaccharides, antibacterial peptides and calcium ions; mixing the mixtures so as to obtain a mixed rana chensinensis extracting liquid; mixing the mixed rana chensinensis extracting liquid with a compounded medicine extracting liquid so as to obtain the compounded traditional Chinese medicinal rana chensinensis extract preparation. The obtained preparation is a traditional Chinese medicinal preparation which has no side effect and can be used for supplying sufficient nutrition to cells and restoring injured cells, wherein the antibacterial peptides can be combined with the calcium ions so as to enhance a bactericidal effect. The obtained preparation is nonirritating to skin mucosa, rapid in bactericidal speed, rapid in curing of nidus positions, simple and convenient to use, colorless and odorless, and is suitable for people in different ages.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a compound preparation of traditional Chinese medicine extracted from forest frogs and its application in preparing medicines and cosmetics for treating acne. Background technique [0002] Acne is a chronic inflammatory disease that is prone to occur in the pilosebaceous glands. It is prone to occur on the face, chest and back. It is characterized by comedones, papules, pus, nodules, cysts and scars, often accompanied by seborrhea. Occurs mainly in young men and women, is also called "whelk", and was called facial sores, wine thorns, lung wind, etc. in ancient times. However, with the increase of life pressure and the influence of comprehensive factors, the age of onset of acne tends to increase. The condition is lingering and difficult to heal and leaves scars, which not only affects the appearance, but also brings serious mental bu...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61K8/98A61K9/107A61K9/06A61K9/08A61P17/10A61Q19/00A61K35/64A61K35/56
Inventor 刘艳孟庆繁王迪付珧谢晶逯家辉张杰刘瑜滕美玉滕利荣姜丹孟珈同
Owner JILIN UNIV
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