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Pelvic inflammation treating tablet and preparation method thereof

A technology of Penyanjing and Jingping tablets, which is applied in the field of medicine, can solve the problems of slow product onset, difficulty in determining the curative effect, and high viscosity of the whole extract, and achieve the problems of improving dissolution rate, solving slow disintegration, and improving dissolution rate Effect

Inactive Publication Date: 2014-09-03
HUNAN PALLADIUM PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the large amount of prescription of raw materials in this product and the high viscosity of the whole extract, it is difficult to form; at present, there are 13 domestic pharmaceutical factories producing Penyanjing Tablets, and the Penyanjing Tablets on the market all use the existing low-cost pharmaceutical excipients , such as starch, dextrin, etc., as fillers and disintegrants, but after being processed into tablets, the disintegration time is longer, resulting in slow onset of the product and difficult to determine the curative effect

Method used

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Effect test

Embodiment 1

[0033] 1.1 The percentage by weight of the adjuvant of the Penyanjing tablet of the present invention accounts for the total weight of the tablet is as follows:

[0034] Lactose 10%, sodium carboxymethyl starch 3%, microcrystalline cellulose 2%, micropowder silica gel 2%, medicinal ethanol 6%.

[0035] 1.2 The preparation method of Penyanjing tablet of the present invention

[0036] (1) First weigh lactose, sodium carboxymethyl starch, microcrystalline cellulose, micropowdered silica gel, medicinal ethanol according to the proportioning; then mix lactose, micropowdered silica gel and microcrystalline cellulose;

[0037] (2) Add half the weight of the mixture of lactose, micropowder silica gel and microcrystalline cellulose to the Penyanjing thick paste, mix well, dry in vacuum at 60-70°C, and then pulverize into fine powder;

[0038] (3) Add the remaining lactose, micropowder silica gel and microcrystalline cellulose mixture to the pulverized fine powder, and add half of the ...

Embodiment 2

[0042] 2.1 The percentage by weight of the adjuvant of the Penyanjing tablet of the present invention accounts for the total weight of the tablet is as follows:

[0043] Lactose 35%, sodium carboxymethyl starch 1%, microcrystalline cellulose 5%, micropowder silica gel 0.5%, medicinal ethanol 15%.

[0044] 2.2 The preparation method of Penyanjing tablet of the present invention

[0045] 1.2 with embodiment 1.

Embodiment 3

[0047] 3.1 The percentage by weight of the adjuvant of the Penyanjing tablet of the present invention accounts for the total weight of the tablet is as follows:

[0048] Lactose 25%, sodium carboxymethyl starch 2%, microcrystalline cellulose 3%, micropowder silica gel 1%, medicinal ethanol 10%.

[0049] 3.2 The preparation method of Penyanjing tablet of the present invention

[0050] 1.2 with embodiment 1.

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Abstract

The invention provides a pelvic inflammation treating tablet and a preparation method thereof, and belongs to the technical field of medicines. The pelvic inflammation treating tablet comprises the following auxiliary materials by weight percent according to the total weight of the tablet: 10-35% of lactose, 1-3% of sodium carboxymethyl starch, 2-5% of microcrystalline cellulose, 0.5-2% of superfine silica powder and 6-15% of medicinal ethanol. Undissolved tablets of traditional Chinese medicine tablets are changed into soluble tablets and instant tablets, so that the problems that all extract tablets of the traditional Chinese medicine are slow to disintegrate and slow to take effect are fundamentally solved, the bioavailability of the traditional Chinese medicine product is improved, and the clinical curative effect of the product is enhanced. The novel medicinal auxiliary materials are refined, and the components are scientific, so that the disintegration time limit of the product is accelerated by 3-4 times on the original basis, the dissolution rate of effective components in the product is increased, and the inherent quality of the traditional Chinese medicine tablet is greatly improved.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a Penyanjing tablet and a preparation method thereof. Background technique [0002] Penyanjing Tablet is a national 8th category of traditional Chinese medicine new drug, a national medical insurance product, and a national non-prescription drug. [0003] Penyanjing Pian comes from the famous traditional Chinese medicine prescription "Puji Fang" edited by Zhu Di and others in the Ming Dynasty. It is widely used in Guangdong, Yunnan and Hunan for various gynecological inflammations, and its curative effect is remarkable. This product is carefully composed of traditional Chinese medicines such as Milletah, Lonicerae, Motherwort, and Radix Paeoniae Rubra, and is refined by modern scientific technology. Pelvic inflammatory disease, adnexitis, cervicitis, endometritis, vaginitis, increased leucorrhea, etc. It is the best choice for the prevention and treatment of various gynecologic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K9/20A61K47/38A61K47/36A61K47/26A61K47/04A61P15/00
Inventor 魏祥符邝颖达
Owner HUNAN PALLADIUM PHARMA
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