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Dendrobium buccal tablets and preparation method for same

A technology for buccal tablets and dendrobium tablets is applied in the directions of food preparation, medical preparations containing active ingredients, pharmaceutical formulations, etc. , good taste effect

Active Publication Date: 2013-09-11
CHONGQING ACAD OF CHINESE MATERIA MEDICA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If no creative work is done, the prepared buccal tablets will have a non-greasy feeling after the entrance, which is often a problem that makes developers more headaches

Method used

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  • Dendrobium buccal tablets and preparation method for same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] The preparation of embodiment 1 superfine powder

[0059]Remove impurities and wash fresh strips of Dendrobium candidum or Dendrobium nobile, remove the outer skin of the washed fresh strips, and use a hot solution of citric acid with a mass percentage concentration of 0.08% at 85°C for 8 minutes for blanching, greening and color protection , after cooling, dry at 55°C to make the water content 70%, slice it into 1mm, and dry it at 60°C to make the water content 3%, pulverize it for 20 minutes with an ultrafine pulverizer to get dendrobium ultrafine powder. The particle size of ultrafine powder can reach 5μm.

Embodiment 2

[0060] The preparation of embodiment 2 superfine powder

[0061] Clean the fresh strips of Dendrobium officinale or Dendrobium nobile to remove impurities, remove the outer skin of the washed fresh strips, dry them at 55°C so that the water content is 70%, slice them into 2 mm, and dry them at 60°C When making it water content be 3%, carry out coarse pulverization, after being pulverized into fine powder, pulverize 20 minutes with superfine pulverizer, obtain the dendrobium superfine powder.

[0062] Compared with Example 2, the technical innovation of Example 1 lies in 1) The acid liquid blanching, which is rarely used to kill enzymes and protect the color of medicinal materials, is used in the preparation of Dendrobium dendrobii to prevent discoloration and oxidation. This treatment has a great effect on improving the sensory evaluation of the later tablet. 2) The thickness of the slices of dried Dendrobium, as shown by many tests, only when the thickness of the slices of D...

Embodiment 3

[0064] The preparation of embodiment 3 dendrobium tablet

[0065] a recipe

[0066] The formula of described dendrobium buccal tablet is composed of the following components in parts by weight:

[0067] Dendrobium superfine powder 400g, prepared by the method of Example 1;

[0068] Mannitol 300g;

[0069] 3000g white sugar powder;

[0070] Citric acid 8g;

[0071] Magnesium stearate 3g;

[0072] Micronized silica gel 5g.

[0073] Two craft

[0074] 1) Mixing: Fully mix the dendrobium superfine powder, mannitol and white sugar powder in the formula amount, and pass through an 80-mesh sieve to obtain the mixture;

[0075] 2) Making soft material: mixing the mixture described in step 1) with ethanol to obtain soft material, and the mass percentage concentration of ethanol in the soft material is 50%;

[0076] 3) Granulation: pass the obtained soft material through 24 meshes, and dry it at 65°C to make the water content 3%, to obtain granules;

[0077] 4) Tablet compressi...

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Abstract

The invention belongs to the field of traditional Chinese medicines or healthcare foods, relates to a dendrobium preparation, and in particular relates to dendrobium buccal tablets. The formula of the dendrobium buccal tablets is composed of dendrobium ultra-fine powder, mannitol, white granulated sugar powder, magnesium stearate, aerosol, citric acid, borneol / menthol, mint oil and mint essence, wherein under the formula aforementioned, wet granulation is performed, and then tabletting is performed to prepare the buccal tablets; and the dendrobium buccal tablets prepared by the formula are high in bioavailability and good in taste. Additionally, the invention further discloses a preparation process for dendrobium ultra-fine powder. The preparation process specifically comprises the following steps of: peeling the cleaned fresh dendrobium bars; drying and slicing to achieve a thickness of not greater than 1 mm; and performing drying treatment at 50-60 DEG C to cause the water content to be 2-3%, and crushing for 10-30 minutes by an ultra-fine crusher, so as to obtain the dendrobium ultra-fine powder. According to the process, the loss rate of the precious medicine of dendrobium is further reduced by optimizing the slice thickness and omitting the step of processing crude powder.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine or health food, in particular to the preparation of dendrobium. Background technique [0002] Dendrobium, one of the Orchidaceae plants, as a valuable medicinal material, is mainly distributed in tropical and subtropical Asia, Australia and Pacific Islands. In my country, most of them are distributed in Southwest China, South China, Taiwan and other places. As medicinal materials or food materials, the sources are mostly the fresh or dried stems of Dendrobium nobile and Dendrobium officinale, perennial herbs of the Orchidaceae family. Dendrobium contains a large amount of dendrobine and polysaccharide mucus; among them, dendrobine has a certain analgesic and antipyretic effect, which is similar to phenacetin but weaker; dendrobium polysaccharide can enhance the body's immune function and has anti-tumor activity. However, with the conventional decoction method, the active ingredients o...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61K9/20A61P11/04A23L1/29A23L33/00
Inventor 詹永杨大坚吴振任昌琼
Owner CHONGQING ACAD OF CHINESE MATERIA MEDICA
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