Application of compound omeprazole in preparation of information treatment drug, preparation method of compound omeprazole, and prepared novel drug

Abstract

The invention discloses an application of compound omeprazole in the preparation of information treatment drug, a preparation method of the compound omeprazole, and a prepared novel drug. The information treatment drug is characterized in that the drug is not contacted with a human body directly in the treatment, the substance ingredient of the drug cannot be consumed, only the drug information is used for physical treatment, and the chemical treatment effect can be achieved, a treatment window is enlarged by more than 1000 times, and the side effects of the chemical treatment are avoided. After the omeprazole is used as the information treatment drug, the contents of active ingredients are not changed, and the omeprazole can be used as the conventional preparation of the chemical treatment for secondary effective use.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a novel medicine of omeprazole. Background technique [0002] Compound omeprazole (Omeprazole), is 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1Hbenzene And imidazole, chemical formula C 17 h 19 N 3 o 3 S, molecular weight 345.42. The properties are white or off-white crystalline powder, odorless, easy to change color when exposed to light. Insoluble in water, slightly soluble in methanol or ethanol, soluble in 0.1mol / L sodium hydroxide solution, easily soluble in dichloromethane. Omeprazole is a proton pump inhibitor, clinically used in the treatment of gastric and duodenal stress ulcers, reflux esophagitis, gastrinoma, etc. The pharmaceutical preparations of omeprazole include tablets, capsules, etc. The known omeprazole drugs are all used as chemotherapeutic drugs, which is to allow the compound omeprazole molecules to enter the human body (through oral ab...

AI Technical Summary

Problems solved by technology

Omeprazole is used as chemotherapeutic drug in the prior art, has the defect that cannot be overcome up to now, the one, to the toxic side effect of human body, its nasty adverse reaction comprises cardiovascular system chest pain, palpitation, tachycardia Or slow, elevated blood pressure, peripheral edema, neuropsychiatric headache, dizziness, weakness, fatigue, paresthesia, depression, anxiety, apathy, confusion, drowsiness, sleepiness, agitation, insomnia, nervousness, aggressive behavior, tremor, Peripheral neuritis, etc., hyponatremia in the endocrine system, gynecomastia, pyuria in the urinary system, proteinuria, hematuria, frequent urination, interstitial nephritis, etc., dry mouth in the gastrointestinal tract, fear of eating, nausea and vomiting, loss of appetite, acid reflux, Abdominal distension, abdominal pain, diarrhea, gastrointestinal discomfort, liver failure, jaundice hepatitis, liver necrosis and blood system reaction, hemolytic anemia, leukopenia and blurred vision, etc.

The second is that the treatment window is small. Due to the toxic and side effects on the human body, the effective dose that can be used is very small, which limits the therapeutic effect. The maximum dose of oral administration is 40 mg once, 80 mg a day, and poisoning can be caused if the maximum dose is exceeded; Chemotherapeutic drugs are only used for one purpose, and the drugs are metabolized or excreted when they enter the human body, and cannot be used again

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