Method for preparing chitosan oligosaccharides through semi-wet method microwave treatment

Abstract

A method for preparing chitosan oligosaccharides through semi-wet method microwave treatment relates to a production method of chitosan oligosaccharides. The method comprises the following steps: using chitosan gelatine powder as raw material to perform hydration and microwave treatment, dissolving in water, neutralizing, and performing membrane separation, drying and the like to prepare chitosan oligosaccharides. The method does not consume organic solvent, thus the problem of recycling solvent does not exist and the pollution is low; and as the volume of the reaction system is from 1 / 3 to 1 / 5 of that of the solution method, the production efficiency is obivously increased. The method adopts microwave treatment to promote the polysaccharide degradation reaction, thus the heating effect is greatly increased. The radiation thermal effect of microwave and the non-thermal effect of microwave are utilized to prepare the product. Meanwhile, microwave is an efficient and clean energy, thus the speed of the chemical reaction can be greatly increased. The method also adopts the membrane separation mean, thus the refining efficiency is high and the product quality is controllable.

Description

technical field [0001] The invention relates to a production method of chitosan oligosaccharide. Background technique [0002] Chitooligosaccharide is a degradation product of chitosan, generally with a molecular weight of less than 3000 and 2 to 15 sugar chain units. As a new class of physiologically active substances, oligochitosan has been shown by many studies to have the physiological function of inhibiting tumors. Its mechanism of action is mainly that after the combination of acetylglucosamine residues and macrophage surface receptors, macrophages are activated, T cell differentiation is accelerated, and the body’s immunity to tumor cells is improved. Oligochitosan can be used as a therapeutic drug for early tumors. At present, it has become a hot spot of development at home and abroad. Oligochitosan has a significant effect on the resistance to diseases and insect pests and growth promotion of many varieties of fruits, vegetables and grains. Dressing wheat seeds wi...

AI Technical Summary

Problems solved by technology

[0004] At present, the degradation of polysaccharides mainly includes chemical and enzymatic degradation, but both chemical and enzymatic degradation are carried out in solvents or solutions, which have the disadvantages of low production efficiency, many pollutants, and high energy consumption.