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Composite nanoemulsion used for epidermis repair and preparation method thereof

A technology of epidermis repair and nanoemulsion, which is applied in the fields of biomedicine, skin care and beauty cosmetics, and can solve problems such as stability and heat resistance of functional ingredients that cannot be solved

Inactive Publication Date: 2010-07-28
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(2) How to protect the activity and content of heat-labile and high-temperature functional ingredients, especially active substances such as proteins, peptides, enzymes, and cell growth factors, so as to improve the stability of protein and polypeptide drugs or functional ingredients. To maintain its biological activity and biological effect to the maximum extent, this is the problem that ordinary dosage forms cannot solve the stability of functional ingredients

Method used

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  • Composite nanoemulsion used for epidermis repair and preparation method thereof

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Embodiment Construction

[0092] A preparation method of composite nanoemulsion for epidermis repair.

[0093] A preferred weight ratio of raw materials for a composite nano-emulsion for epidermis repair is: isopropyl myristate 12.25, caprylic capric acid macrogolglyceride 29.1, polyglycerol fatty acid ester 9.7, distilled water 39.2769, EDTA-2NA 0.087, citric acid 0.437, sodium citrate 1.27, glycine 0.874, trehalose 1.75, metallothionein 0.005, epidermal growth factor 0.0001, vitamin E 1.75, vitamin A1.75, yellow and white purple flower oil (astragalus, angelica, comfrey, peanut oil complex) 1.75.

[0094] A kind of concrete preparation method and implementation example of the composite nanoemulsion that is used for epidermis repair (take preparation 100g as example):

[0095] ① Weigh 39.2769g of water and place it in a 100mL Erlenmeyer flask, then dissolve and add 0.087g EDTA-2NA, 0.437g citric acid, 1.27g sodium citrate, 0.874g glycine, 1.75g ​​trehalose, 0.005g metallothionein, 0.0001 g epidermal...

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Abstract

The invention relates to the technical fields of the biomedicine and the skin health-care and facial cosmetics, in particular to a composite nanoemulsion used for epidermis repair and a preparation method thereof. The product prepared in the invention can quicken the injured epidermis repair and the epidermis barrier function repair, can improve the stability of protein polypeptide drugs or efficacy compositions and enhance the dissolvability of the difficultly dissolved matter and the stability of the easily hydrolyzed matter by promoting the skin to permeate and absorb the efficacy compositions of the epidermis, can scientifically and reasonably match natural drugs, antioxidants and biological derived skin repair polypeptide, and can exert the better epidermis repair efficiency and speed by combining the high-efficiency skin delivery carrier blank nanoemulsion system. Moreover, the product prepared in the invention can also improve the nutrition and moisturizing capabilities of the skin greatly, create an appropriate micro-ecological environment for the epidermis repair and enhance the synergism of the efficacy compositions. In addition, the product prepared in the invention can not contain the preservative and the essence, lowers the toxicity, improves the safety and can be industrially produced without adopting special equipment and energy.

Description

technical field [0001] The invention belongs to the technical fields of biomedicine, skin care and beauty cosmetics, and relates to a composite nanoemulsion for epidermis repair and a preparation method thereof. Background technique [0002] Human skin is soft and smooth when young, but with the growth of age, seasonal changes, excessive sun exposure, lack of sleep, work pressure, life beauty, professional beauty, medical beauty and plastic beauty Exfoliation, massage and overuse of some corrosive medicated or nutrient masks, peeling after chemical peels, redness and hair removal, post-sun UV burns, acne, skin burns caused by retinoids and fruit acids, etc. and post-abrasion Conventional or informal over-cosmetology such as deep skin damage can easily cause thinning or damage of the facial epidermis; moreover, abuse of cosmetics, laser or photon cosmetology, plastic surgery, skin aging, skin burns, ulcers and various skin diseases Repair of skin lesions, and even poor diet ...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K8/67A61K8/64A61K8/60A61K8/06A61Q19/00
Inventor 杨永鹏朱晓亮董萍丁克祥左夏林丁宇
Owner 董萍
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