The invention provides a compound composition, in particular to a compound composition containing 2-p-fluorophenyl-5-methylsulfonyl-1,3,4-oxadiazole and thiodiazole copper, wherein the weight ratio of 2-p-fluorophenyl-5-methylsulfonyl-1,3,4-oxadiazole to thiodiazole copper is (20-1):(1-40). Compared with each of 2-p-fluorophenyl-5-methylsulfonyl-1,3,4-oxadiazole and thiodiazole copper, the compound composition provided by the invention has an obvious synergistic effect on bacterial diseases of crops, improves the bactericidal effect, reduces pesticide cost, environmental pollution and pesticide residue, and is conductive to overcoming the generation of pesticide resistance. The compound composition provided by the invention has no obvious adverse effect on tested crops, ensures normal leaf color, growth and the like, has high safety, meets the safety requirements of pesticide preparations and plays a favorable control role on bacterial diseases of crops.