33results about How to "Limit risk" patented technology

The present invention provides pharmaceutical compositions for the treatment of acne, psychotic illnesses, such as schizophrenia, cancer, such as cancer of the head, neck and lung, and emphysema, comprising co-administering a therapeutically effective amount of isotretinoin and a contraceptive in a contraceptively effective dosage. The contraceptive preferably does not contain 100 wt % progestogen. Methods of treating acne and unit dosage delivery systems are also provided. Also provided is an improved method of treating acne, and other diseases, comprising providing a blister pack comprising at least about 28 separate daily dosage units of a therapeutically effective amount of isotretinoin, or other retinoic acid derivative equivalent, and at least about 21-28 additional daily dosage units of an oral contraceptive in a contraceptively effective amount, selected from the group consisting essentially of: estrogen, estrogen and progestogen, mifepristone, or a combination thereof, whereby for at least about 21 successive days, said oral dosage unit of isotretinoin, or other retinoic acid derivative equivalent, and said oral dosage unit of said oral contraceptive are administered to a female of child-bearing age. Patch, inhaler, nebulizer, and injection formulations for the preferred active ingredients are also provided.

Wedging blades attached to the disk of a rotor having slots. According to the invention, each wedging spacer is made of an elastically deformable material and at least one longitudinal segment of the spacer presents a transverse profile of arcuate shape to define two lateral contact zones.

This device has an arrival corridor via which the articles arrive, an article-receiving zone on which a stack (P) of said articles is formed, and a rotary actuator (22) suitable for pushing said articles away against a retaining element (32) for retaining the stack. The actuator (22) has at least one protective member (281, 282) for protecting the last article (N) in the stack (P) being formed, said protective member being suitable for being interposed between said last article and a current article (N+1) coming from the arrival corridor.

A method of stopping an engine of a rotorcraft in overspeed, the engine comprising a gas generator and a power assembly. When the engine is in operation, a relationship is established giving a limit derivative that varies as a function of the speed of rotation of the power assembly. The speed of rotation, referred to as the “current speed”, reached by the power assembly is measured and the time derivative of the speed of rotation is determined and referred to as the “current derivative”. The engine is stopped automatically when the limit derivative corresponding to the current speed as determined by the relationship is less than or equal to the current derivative.

The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof, and methods of manufacturing such antibodies by co-expressing modified Fc-5 mutated derivatives of two different monoclonal antibodies in mammalian cell lines.

The invention relates to a robotic workstation (1), comprising at least one multiple-axis parts-handling robot (7) having an arm (9) with a free end that is provided with a parts support (10), and first and second operational units (5, 6) for co-operating functionally with the support, and wherein the support comprises a body (11) provided with locations (14) for receiving parts, said locations being arranged so that each of them is accessible simultaneously by one of the operational units. The invention also provides a method of controlling the station.

An adjustment device for adjusting the position of the center of gravity of an aircraft, the aircraft having at least two thrust production units that contribute at least to providing the aircraft with lift, the adjustment device comprising at least one heavy member that is movable relative to an airframe of the aircraft and also at least one actuator for causing the heavy member to move. The adjustment device includes an avionics system configured to detect a failure of any one of the thrust production units and, in the presence of such a failure, to control the at least one actuator to cause the heavy member to move.

A roller bearing having a first ring, a second ring, at least one row of rolling elements arranged between the rings, and a cage for keeping the rolling elements circumferential in relation to one another. The cage includes first axial retaining means for the first ring and second axial retaining means for the second ring.

The invention concerns a panel whereof at least one of the upper electrodes is common to a plurality of diodes (5, 5') and comprises a first conductive layer (31) and a second conductive layer (33), and an isolating and transparent buffer layer (32) which is interposed between said two conductive layers (31, 33) and which is perforated with windows which provide direct contact zones (4) between the two conductive layers (31, 33) of said common electrode (3), said contact zones (4) being separated from the active zones of the diodes (5, 5'). The presence of said direct contact zones between the two conductive layers, enables a good distribution of current to be provided by the upper electrode while the intermediate buffer layer is insulating.

The exchange of frames over a network between devices. Each device comprises a communication circuit connected to a processing unit and comprises addresses, each one being associated with a transmission or reception indicator, a single device comprising a same address associated with a transmission indicator. Each address is associated with a memory containing a frame. A master device periodically transmits transmission indicator addresses. The communication circuit of the device for which the transmitted address is associated with a transmission indicator transmits the frame of the memory to said address and provide the processing unit with an identifier of said address. Each communication circuit of a device for which the transmitted address is associated with a reception indicator writes said frame into the memory at said address and provides the processing unit with an identifier of said address.

Lubricating oil distributor for a mechanical reduction gear of a turbine engine, in particular of an aircraft, wherein it has a general annular shape around an axis X and is formed of a single part, the distributor including first and second independent oil circuits, the first oil circuit including a first oil inlet connected by a first annular chamber to several oil outlets, and the second oil circuit including a second oil inlet connected by a second annular chamber to several oil outlets, the first chamber including a section that is at least partially nested in a section of the second chamber.

This female quick coupling (2) element (10) is intended to cooperate, by press fitting (F1) along a press fitting axis (X10-X20), with a male element (20). It comprises a body (102) centred on a longitudinal axis (X10) of the passage of fluid and comprising a flat front face (108), a relief valve (120) comprising a valve (110) housed in the duct for the passage of fluid and mobile along the longitudinal axis, a manoeuvring ring (130) mounted slidingly around the body and defining, at its distal end (134), a mouth (E10) for receiving the male element. The manoeuvring ring is provided with at least one relief (136) of engagement with a corresponding relief (226) of the male element. The female coupling element further comprises a safety ring (150) mounted around the body (102), radially inside the manoeuvring ring (130), mobile axially in relation to the body (102) between a first position and a second position. The female element further comprises means (170, 158) for transforming, when the safety ring (150) is in its second position, a movement of rotation of the manoeuvring ring, about the longitudinal axis (X10) and in relation to the safety ring (150), into a movement of axial translation of the body (102) in relation to the manoeuvring ring (130).

The invention relates to a device for detecting icing and de-icing of a wind turbine blade, characterized in that it comprises: a sensor, placed on the surface of a blade, and comprising a first so-called “receiving” antenna, a second so-called “emitting” antenna, and a frequency divider inserted between said first and second antennas; and an interrogator, configured to emit an electromagnetic wave towards the receiving antenna of said sensor, and to receive an electromagnetic wave from the emitting antenna of said sensor.

Chewing gums and pressed mint products which include plant materials such as leaves and fruit slices adhered on their surface are disclosed. Preferably, the chewing gum or pressed mint piece will have at least one side surface of which a major portion of the area is covered or substantially covered one piece or a few pieces of plant material. The piece of plant material may be large enough in area that it may be identified by the consumer, for example as being a mint leaf or a slice of a strawberry.

A device for implanting radioactive seeds and non-radioactive spacers in a desired configuration in an animal body for effecting radiation therapy. An elongated hollow needle is inserted in the body. A pushing element implants the row of seeds and spacers though the hollow needle towards the desired location. A tube shaped element receives the row of seeds and spacers. A lube shaped sleeve having open ends is used to insert the tube shaped element through the needle and toward the location. The pushing elements pushes the row of seeds and spacers into the desired location while still being carried in the tube shaped element.

A method for preparing metal-matrix composites including cold-process isostatic compaction of previously mixed powders and hot-process uniaxial pressing of the resulting compact is disclosed. The method enables metal-matrix composites with improved properties to be obtained. A device for implementing isostatic compaction comprising a latex sheath into which the mixture of powders is poured, a perforated cylindrical container in which the latex sheath is arranged, and means for sealed insulation of the mixture of powders contained in the sheath is also disclosed.

A device is for detecting a relative positioning of two clock signals including a fast clock signal and a slow clock signal. The fast clock frequency may be n times greater than a slow clock frequency, and n includes an integer greater than 1. The device includes a phase logic signal generator for generating a phase logic signal from the two clock signals by assigning a predetermined logic value to the phase logic signal when a rising edge of the fast clock signal matches a predetermined location of the slow clock signal.