The embodiment of the invention provides a vehicle-mounted game method and device, a vehicle and a machine readable medium. A first user located at a main driving position and a second user located atother positions can be received, control instructions are input by preset control equipment and then responded to respectively, and a virtual object corresponding to each participating user, which isdisplayed by a vehicle-mounted system, is controlled so as to carry out vehicle-mounted games, so that the users in the vehicle can play the vehicle-mounted games through different control equipment;on one hand, the control equipment in the vehicle can be combined with the vehicle-mounted games, so that immersive game experience is brought for the users, and compared with the simple human-computer interaction, the vehicle-mounted game method has stronger interactivity and the sense of substitution; and on the other hand, the interaction among the participating users can be increased, and thevehicle experience of the in-vehicle users is improved.