Disclosed is an automated medicine storage and medicine introduction / discharge management system, which includes a main body in which a plurality of receiving shelves is arranged, the main body having a door to enable user access, a medicine introduction / discharge unit installed in one side region of the main body to introduce or discharge a medicine product into or out of the main body, a robot transfer unit installed in the main body to transfer the medicine product, introduced via the medicine introduction / discharge unit, to each receiving space of the main body, or to discharge the medicine product received in the receiving space, and a control unit to control operations of the main body, the medicine introduction / discharge unit, and the robot transfer unit. The system is able to store a variety of medicine in a single main body and to achieve enhanced security for special medicine and efficient management of stock.