The present invention provides an air-filling cushioning material which can sufficiently inflate cells and, in addition, which can hold the crease of the fold when being formed into a three-dimensional configuration. An air-filling cushioning material 1, in which a plurality of cells 2 having an air-fillable space are formed by adhering overlapped flexible sheets 1a, 1b at predetermined spots wherein one sheet 1a is flat while the other sheet 1b is molded beforehand into a configuration of the cells 2 in inflation at the position where the cells 2 are to be formed. Therefore, there is no such problem, as in the conventional case where the cells are formed by tucking the other sheet, the cells cannot inflate well. The cells 2 formed on the other sheet 1b can inflate sufficiently into a configuration as molded.