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Use of Whey Permeate for the Treatment of Metabolic Syndrome

a metabolic syndrome and whey permeate technology, applied in food preparation, food science, pharmaceutical non-active ingredients, etc., can solve the problems of increasing the risk of secondary diseases, reducing the daily energy release, and promoting an increased risk of secondary diseases

Inactive Publication Date: 2007-10-18
SUK BETEILIGUNGS GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Cause of this alarming development is caloric overnutrition with carbohydrates and fats with further reduction of the daily energy release.
Furthermore, these diseases promote an increased risk of secondary diseases such as arteriosclerosis.
Further health risks caused by the pathological changes associated with diabetes are eye complaints, heart and vascular diseases, stroke, heart attack, kidney diseases, etc.
However, this cannot be properly utilized by the body.
Firstly, IgG antibodies may inhibit the biological efficiency of insulin, thereby increasing the daily demand to above 100 IU (International Units).
As a consequence, an insufficient amount of energy reaches the cells while the blood sugar level remains high.
The constant overproduction of insulin leads to an exhaustion of the insulin-producing beta cells in the pancreas and finally to insulin deficiency.
However, additional drugs are often necessary to reduce blood pressure, blood sugar and blood lipids.

Method used

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  • Use of Whey Permeate for the Treatment of Metabolic Syndrome
  • Use of Whey Permeate for the Treatment of Metabolic Syndrome
  • Use of Whey Permeate for the Treatment of Metabolic Syndrome

Examples

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Embodiment Construction

[0034] It has surprisingly been found that administration of whey permeate to animals recognized as models for metabolic syndrome and type 2 diabetes results in prevention of glucose intolerance and prevention of insulin resistance as well as in a lowering of the triglyceride concentration in the serum.

[0035] Thus, according to the invention, a pharmaceutical composition is provided comprising whey permeate. This pharmaceutical composition is used for the prophylaxis, treatment or prevention of hypertriglyceridemia, glucose intolerance and insulin resistance in metabolic syndrome or type 2 diabetes as well as in secondary diseases arising therefrom in mammals, preferably humans.

[0036] Examples of secondary diseases which accompany metabolic syndrome or diabetes are vascular diseases, coronary insufficiency, arterial occlusive diseases, myocardial infarction, xanthomas, abdominal discomfort, splenohepatomegaly, pancreatitis, retinal lipemia, and / or stroke.

[0037] Whey accumulates d...

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Abstract

The invention relates to the use of whey permeate, preferably sweet whey permeate and more preferably hydrolysed or partially-hydrolysed sweet whey permeate for the production of a pharmaceutical composition for prophylaxis or treatment of symptoms of metabolic syndrome, type-2 diabetes and secondary diseases, said composition being provided for a mammal.

Description

TECHNICAL FIELD [0001] The present invention relates to the treatment of metabolic syndrome or type 2 diabetes. Further disclosed is the use of whey permeate for producing dietary and pharmaceutical compositions for the prevention and treatment of symptoms of metabolic syndrome or type 2 diabetes. PRIOR ART [0002] According to WHO criteria, 63% of all men and 55% of all women in industrialized countries are overweight. Cause of this alarming development is caloric overnutrition with carbohydrates and fats with further reduction of the daily energy release. Even very small differences in the daily energy balance have a large cumulative effect on body mass over the years. A daily caloric input of 0.3% above the caloric consumption thus leads to a gain in weight of 9.1 kg in 25- to 55-year-old Americans. The overweight individuals frequently develop a metabolic syndrome (Reaven G M, Curr. Opin. Lipidol., 1997, 8 (1), p. 23-27). [0003] In connection with the use of the term “metabolic s...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K35/20A61K9/20A61P1/00A61P3/06A61P3/10A61P9/00A61P9/12A23L1/305A23L33/20A61K31/19A61K31/7016
CPCA23L1/3053A23L1/3056A61K35/20A61K31/7016A61K31/19A23L33/18A23L33/19A61P1/00A61P1/04A61P1/16A61P1/18A61P13/12A61P17/00A61P25/08A61P27/02A61P3/00A61P3/10A61P35/00A61P3/06A61P5/50A61P9/00A61P9/02A61P9/10A61P9/12
Inventor KRAUSKOPF, JOBSTSOWADA, CHRISTIAN
Owner SUK BETEILIGUNGS GMBH
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