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Chinese medicinal preparation for cardio-cerebral blood vessel diseases and its making method

A technology of cardiovascular and cerebrovascular diseases and traditional Chinese medicine preparations, which is applied in the field of pharmaceuticals, can solve problems such as large doses, poor craftsmanship, and unsatisfactory curative effects, and achieve the effects of improving curative effect, reducing dosage, and reducing clinical dosage

Active Publication Date: 2005-10-12
SHAANXI BUCHANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But capsules can not fully meet the needs of both doctors and patients, especially some patients are unwilling to take capsules; in addition, the large dosage is also the main problem in the prior art; the applicant found in practice that due to the original patent application documents The process provided in the article is relatively rough, and the curative effect of the obtained product is not satisfactory enough.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] The preparation of embodiment 1 capsule

[0064]Raw material formula: 1320g astragalus, 540g red peony, 540g salvia, 540g angelica, 540g chuanxiong, 540g peach kernel, 260g safflower, 260g frankincense, 260g myrrh, 400g spatholobus, 540g achyranthes bidentata, 400g cassia twig, mulberry branch 540g, earth dragon 540g, scorpion 260g, leech 540g.

[0065] Preparation method: (1) Take Chuanxiong, Angelica, Guizhi, frankincense, and myrrh and grind them into coarse powder, add 10 times the amount of water to soak for 1 hour, steam distillation for 6 hours, collect volatile oil, and use 4 times the amount of β- Cyclodextrin is made into clathrate to obtain volatile oil β-cyclodextrin clathrate, medicinal dregs and medicinal liquid for later use;

[0066] (2) Take Salvia miltiorrhiza, extract 1.5 hours with 4 times the amount of 95% ethanol at a time, extract 2 times altogether, filter the extract, combine the filtrate, recover ethanol under reduced pressure, concentrate, an...

Embodiment 2

[0070] The preparation of embodiment 2 tablet

[0071] Ingredients: 660g astragalus, 270g red peony, 270g salvia, 270g angelica, 270g chuanxiong, 270g peach kernel, 130g safflower, 130g frankincense, 130g myrrh, 200g spatholobus, 270g achyranthes bidentata, 200g cassia twig, mulberry branch 270g, earthworm 270g, scorpion 130g, leech 270g.

[0072] Preparation method: (1) Take Chuanxiong, Angelica, Guizhi, frankincense, and myrrh powder, add 12 times the amount of water, steam distillation for 4 hours, collect volatile oil, and use 6 times the amount of hydroxypropyl β-cyclodextrin Prepare clathrates to obtain volatile oil cyclodextrin clathrates, medicinal residues and medicinal liquid for subsequent use;

[0073] (2) Take Salvia miltiorrhiza, extract 0.7 hours with 6 times of 85% ethanol at a time, extract 3 times in total, filter the extract, combine the filtrates, recover ethanol under reduced pressure, concentrate, and dry to obtain the tanshinone extract, Salvia miltiorr...

Embodiment 3

[0077] The preparation of embodiment 3 granules

[0078] Ingredients: 660g astragalus, 270g red peony, 270g salvia, 270g angelica, 270g chuanxiong, 270g peach kernel, 130g safflower, 130g frankincense, 130g myrrh, 200g spatholobus, 270g achyranthes bidentata, 200g cassia twig, mulberry branch 270g, earthworm 270g, scorpion 130g, leech 270g.

[0079] Preparation method: (1) Take Rhizoma Chuanxiong, Angelica, Guizhi, Frankincense, and Myrrh, grind them into coarse powder, put them in a supercritical extraction kettle, and extract them for 1.8 hours at an extraction pressure of 29Mpa and an extraction temperature of 40°C to collect volatile oil. After inclusion compounding with 4 times the amount of β-cyclodextrin, the inclusion compound of volatile oil cyclodextrin is obtained, and the dregs and liquid medicine are ready for use;

[0080] (2) Take Salvia miltiorrhiza, percolate with 6 times the amount of 90% ethanol, collect the percolation liquid, recover under reduced pressur...

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Abstract

A Chinese medicine in the form of tablet, capsule, particle, or oral liquid for treating cardiovascular and cerebrovascular diseases is prepared from 16 Chinese-medicinal materials including Chuan-xiong rhizome, Chinese angelica root, red peony root, astragalus root, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and a preparation method thereof, belonging to the technical field of medicines. Background technique [0002] Stroke and chest obstruction are cardiovascular and cerebrovascular diseases, which are common and frequently-occurring diseases that seriously endanger human health, especially the health of middle-aged and elderly people. At present, there is no good curative drug. The applicant submitted a patent application titled "A Traditional Chinese Medicine Capsule and Its Preparation Method That Can Be Used for Treating Stroke and Chest Constipation" to the Chinese Patent Office in 2001, and the publication number is 1406609. It is a capsule made of 16 Chinese herbal medicines such as Astragalus, Salvia, Angelica, Chuanxiong, and Radix...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P9/00A61P9/10
Inventor 赵涛
Owner SHAANXI BUCHANG PHARMA
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