Musk precordial pain relieving drop pills and preparation method thereof

A technology of musk and dripping pills, applied in the directions of pill delivery, pharmaceutical formulations, cardiovascular system diseases, etc., can solve the problems of long dissolution time, low bioavailability, unfavorable for critically ill patients and allergic patients, etc., to avoid gastrointestinal tract. Irritant symptoms, accelerated dissolution and absorption, improved bioavailability

Inactive Publication Date: 2005-07-06
北京博智绿洲医药科技有限公司
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

[0012] Although traditional Chinese medicine ointment for external use is a traditional dosage form of traditional Chinese medicine, due to its backward preparation process and low utilization rate of raw and auxiliary materials, it cannot better meet the requirements of industrialized large-scale production; in addition, its bioavailability is low, the dosage is large, and it is inconvenient to store, carry and use , not conducive to critically ill patients and allergic patients and outdoor use in winter
[0013] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect

Method used

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Examples

Experimental program
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Embodiment Construction

[0042] Now with several groups of specific examples, the preparation method of the Shexiang Xintong dripping pills of the present invention will be further described.

[0043] Group 1: Tests with a single matrix

[0044]1. Weigh a certain amount of drug raw materials according to the ratio given in [Preparation Method] 1, and then follow [Appendix 1: A preparation method for medicinal thick paste or dry powder], [Appendix 2: Preparation of Angelica dahurica liquid extract] and [Appendix 3: Preparation of Pig Tooth Soap Extract] The given method firstly prepares the active ingredients of the medicine containing musk, angelica liquid extract, pig tooth soap liquid extract, borneol, methyl salicylate, camphor, and diphenhydramine hydrochloride dry powder for use;

[0045] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glyc...

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PUM

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Abstract

The invention relates to a medicinal oral preparation of musk drop pill with the functions of arousing coma, relieving pain and treating precordial pain, chest pain, the drop pill has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, low price, and facilitated carrying. The medicine is prepared through the conventional drop pill preparing process.

Description

technical field [0001] The present invention relates to a kind of medicinal composition which has the effects of aromatic resuscitation, regulating qi and relieving pain, and is used for treating chest obstruction and heartache caused by qi stagnation and blood stasis, such as chest obstruction, chest pain, suffocation and other symptoms. Basic, a kind of pharmaceutical composition oral drop pill preparation that forms through dosage form reformation. Background technique [0002] According to the formula and preparation process given in the national drug standard WS-10579 (ZD-0579)-2002, Musk Heart Pain Ointment is prepared, which has the functions of aromatic resuscitation, regulating qi and relieving pain, and is used to treat diseases caused by stagnation of qi and blood stasis. Chest obstruction and heart pain, oral Chinese medicine preparations for symptoms such as chest obstruction, chest pain, and suffocation, have been clinically verified to have stable quality and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P9/10
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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