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Injectio of aspirin and dipyridamole and its preparing process

A technology of dipyridamole and aspirin, which is applied in the field of medicine and its preparation, and can solve the problems that there are no reports on injection dosage forms.

Inactive Publication Date: 2005-07-06
崔晓廷
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But its injection form has not seen any report

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0006] Embodiment 1: It is prepared from 150 grams of aspirin and 50 grams of dipyridamole. 150 grams of aspirin and 50 grams of dipyridamole are mixed with 5000 ml of water for injection, which are made into injection according to the prior art. The preparation does not add any excipients.

Embodiment 2

[0007] Embodiment 2: It is prepared from 75 grams of aspirin and 25 grams of dipyridamole. 75 grams of aspirin and 25 grams of dipyridamole are mixed with 5000 ml of water for injection, which are made into injection according to the prior art. The preparation does not add any excipients.

Embodiment 3

[0008] Embodiment 3: it is prepared from 225 grams of aspirin and 75 grams of dipyridamole. In the production process, 250000ml of water for injection is mixed, and a large-capacity infusion is made according to the prior art.

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PUM

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Abstract

The invention provides an injection of aspirin and dipyridamole and its preparing process, which comprises aspirin and dipyridamole by the proportion of aspirin : dipyridamole = 1-99 : 99-1, the injection can be made into the forms of injection, freeze-dried powder injection, germ-free powder injection, and high capacity fluid infusion. The preparation can be applied for treating cardiovascular and cerebrovascular diseases.

Description

Technical field: [0001] The invention relates to aspirin-dipyridamole compound injection and a preparation method thereof, and belongs to the technical field of medicines and preparation methods thereof. Background technique: [0002] Antiplatelet aggregation is an important link in the treatment of cardiovascular and cerebrovascular diseases. Aspirin is the first-generation anti-platelet aggregation drug, which can prevent thrombosis and is used to prevent transient ischemic attack, myocardial infarction, atrial fibrillation, unstable angina, etc. Dipyridamole also has antithrombotic effects. It inhibits the first and second phase aggregation of platelets. At high concentrations, it can inhibit the release response of platelets. The second drug is commonly used in thromboembolic diseases and ischemic heart disease. The latest results of modern medical research emphasize this idea: the combined use of anti-platelet aggregation drugs with different mechanisms of action ca...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K31/616A61P7/02
Inventor 崔晓廷
Owner 崔晓廷
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