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Composition for treating chloasma and preparation method thereof

A composition and technology for chloasma, applied in the directions of drug combination, medical raw materials derived from Ginkgo biloba, medical preparations containing active ingredients, etc., can solve the problem of low bioavailability of raw materials, little effect of treatment methods, and absorption of finished products problems such as poor effect, to achieve the effect of improving bioavailability, improving therapeutic effect and easy absorption

Inactive Publication Date: 2022-01-11
杨业 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chloasma skin lesions themselves rarely bring pain or discomfort to patients, but because they often occur on the face and affect their appearance, they bring certain psychological pressure to patients, and this adverse effect will further aggravate the skin lesions. Many treatments are ineffective
Nowadays, the research on the reagents for the treatment of chloasma is getting more and more in-depth. Various reagents and health care products for the treatment of chloasma are also emerging in the market, but there is a common problem. More chemical reagents will be added in the selection of raw materials. , there will be some safety hazards in long-term use, and the treatment effect is average, and it is difficult to cure, and can only achieve a marked effect
Although there are many researches on the preparation of preparations using plant ingredients, often because the processing technology uses conventional extraction, stirring and mixing methods, on the one hand, the bioavailability of raw materials is not high, and on the other hand, the finished product is absorbed during use. poor effect

Method used

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  • Composition for treating chloasma and preparation method thereof
  • Composition for treating chloasma and preparation method thereof

Examples

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Effect test

preparation example Construction

[0029] A preparation method for treating chloasma, comprising the steps of:

[0030] (1) Preparation of extract:

[0031] A. Weigh 30 to 40 parts of chamomile, 30 to 40 parts of dandelion, 8 to 14 parts of ginkgo biloba, and 8 to 12 parts of Angelica dahurica in corresponding weight parts, and place them in a cryogenic pulverizer for pulverization, and control the temperature of the pulverizer The temperature is -12~-4℃, the time for crushing treatment is 30~38min, and the mixed powder is obtained after completion;

[0032] B. Put the mixed powder obtained in operation A into cold plasma equipment for cold plasma treatment, the power is 80-120W, and take it out after 6-10 minutes of treatment for later use;

[0033] C. Place the mixed powder after the cold plasma treatment in operation B in a Soxhlet extraction device for reflux extraction, and collect the extract and filter residue for subsequent use;

[0034] D. Purifying and concentrating the extract obtained in operation...

Embodiment 1

[0043] A preparation method for treating chloasma, comprising the steps of:

[0044] (1) Preparation of extract:

[0045] A. Weigh 30 parts of chamomile, 30 parts of dandelion, 8 parts of ginkgo biloba, and 8 parts of Angelica dahurica in corresponding weight parts and place them in a cryogenic pulverizer for pulverization. The temperature of the pulverizer is controlled at -12°C. The time is 30 minutes, and the powder must be mixed for later use;

[0046] B. Place the mixed powder obtained in operation A in a cold plasma device for cold plasma treatment with a power of 80W, and take it out after 6 minutes of treatment for later use;

[0047] C. Place the mixed powder after the cold plasma treatment in operation B in a Soxhlet extraction device for reflux extraction, and collect the extract and filter residue for subsequent use;

[0048] D. Purifying and concentrating the extract obtained in operation C to obtain an extract for subsequent use;

[0049] (2) Steam flash explosi...

Embodiment 2

[0056] A preparation method for treating chloasma, comprising the steps of:

[0057] (1) Preparation of extract:

[0058] A. Weigh 35 parts of chamomile, 35 parts of dandelion, 11 parts of ginkgo biloba, and 10 parts of Angelica dahurica in corresponding weight parts and place them in a cryogenic pulverizer for pulverization. The temperature of the pulverizer is controlled at -8°C. The time is 34 minutes, after the completion, the mixed powder is ready for use;

[0059] B. Place the mixed powder obtained in operation A in a cold plasma device for cold plasma treatment, with a power of 100W, and take it out for use after 8 minutes of treatment;

[0060] C. Place the mixed powder after the cold plasma treatment in operation B in a Soxhlet extraction device for reflux extraction, and collect the extract and filter residue for subsequent use;

[0061] D. Purifying and concentrating the extract obtained in operation C to obtain an extract for subsequent use;

[0062] (2) Steam f...

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Abstract

The invention discloses a composition for treating chloasma and a preparation method thereof, and belongs to the technical field of chloasma treatment preparations. The preparation method comprises the following steps of: (1) preparing extract paste; (2) performing steam flash explosion; (3) performing micro-jet high-pressure homogenization treatment; and (4) performing ultrasonic-ultraviolet-magnetic field coupling treatment. According to the composition for treating chloasma and the preparation method thereof, firstly, the selected raw materials are traditional Chinese medicines, vegetables and fruits with mild temperament, and the raw materials are safe; secondly, by combining and applying the technologies of cryogenic grinding, cold plasma treatment, steam flash explosion, micro-jet high-pressure homogenization treatment, ultrasonic waves and the like, the fusion among the raw materials is promoted, the bioavailability of the raw materials is improved, the interaction among the raw materials is promoted, the finished product is refined while sterilization is performed, and the composition is easy to absorb, so that the raw materials can synergistically act on the skin, and the composition has a remarkable treatment effect on chloasma.

Description

technical field [0001] The invention belongs to the technical field of preparations for treating chloasma, and in particular relates to a composition for treating chloasma and a preparation method thereof. Background technique [0002] Chloasma is a common pigmentation disease that occurs on the face. Dermatosis is more likely to occur on the cheekbones and forehead. It is manifested as symmetrical and localized light yellow to dark brown patches on the face. Clinically, this disease is more common in young and middle-aged women, but a few men also suffer from it. Patients with chloasma generally have no symptoms and mainly affect their appearance. The etiology and pathogenesis of this disease are not very clear so far. It is generally believed that the disease is related to many factors such as endocrine disorders, heredity, oxygen free radicals, ultraviolet radiation, mental factors, use of contraceptives, cosmetics for external use, and many other factors. Healing is a ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/62A61P17/00
CPCA61K36/28A61K36/288A61K36/16A61K36/232A61K36/62A61K36/428A61K36/185A61P17/00A61K2236/15A61K2300/00
Inventor 杨业吴芳
Owner 杨业
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