Mouthwash containing swimming nano robot and used for active prevention and treatment of oral cavity

A nano-robot and mouthwash technology, applied in nanotechnology, oral care, nanotechnology, etc., can solve the problems of difficult to achieve high-efficiency drive, antibacterial drugs can not be reached, mouthwash has no initiative, etc., to achieve good biocompatibility and Effects of biodegradability, strong driving force, and simple preparation process

Pending Publication Date: 2021-12-28
HARBIN INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims to solve the problem that the existing mouthwash has no initiative, and the locally applied antibacterial drugs in the mouthwash cannot reach the bottom of the deep and narrow periodontal pocket. However, it is difficult to achieve efficient driving by using the existing nano-robots in the mouthwash, or There is a problem of cumbersome preparation process, and a mouthwash containing swimming nanorobots for oral active prevention and treatment is provided

Method used

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  • Mouthwash containing swimming nano robot and used for active prevention and treatment of oral cavity
  • Mouthwash containing swimming nano robot and used for active prevention and treatment of oral cavity
  • Mouthwash containing swimming nano robot and used for active prevention and treatment of oral cavity

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specific Embodiment approach 1

[0016] Specific implementation mode one: combine figure 1 and figure 2 Specifically, a mouthwash containing swimming nanorobots for oral active prevention and treatment described in this embodiment includes component A and component B, and the volume ratio of component A to component B is ( 5~10): 1; The component A is composed of 0.5%~3% hydrogen peroxide, 3%~5% alcohol, 3%~5% glycerin, 0.1%~0.3% carboxymethyl cellulose by mass percentage . or sorbitol;

[0017] The swimming nanorobot is composed of an antibacterial and anti-inflammatory drug, a hollow capsule skeleton and an enzyme catalyst, and the antibacterial and anti-inflammatory drug is coated inside the hollow capsule skeleton, and the enzyme catalyst is located on one side of the hollow capsule skeleton; the hollow capsule The diameter of the skeleton is 300 nm to 100 μm.

[0018] Component A and component B in this specific embodiment are filled and packaged respectively to obtain finished products.

[0019] T...

specific Embodiment approach 2

[0028] Embodiment 2: This embodiment differs from Embodiment 1 in that: the hollow sac-shaped skeleton is formed of a biocompatible and degradable polymer; the biocompatible and degradable polymer The polymer is polyvinyl alcohol, polyethylene glycol amphiphilic block polymer, dextran and chitosan. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0029] Embodiment 3: This embodiment differs from Embodiment 1 or Embodiment 2 in that: the enzyme catalyst is catalase, peroxidase, platinum nanoparticles or iron ferric oxide nanoparticles. Others are the same as in the first or second embodiment.

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Abstract

The invention relates to mouthwash containing a swimming nano robot, in particular to mouthwash containing the swimming nano robot and used for active prevention and treatment of an oral cavity. The mouthwash aims to solve the problems that existing mouthwash has no initiative, an antibacterial drug locally applied in the mouthwash cannot reach a deep and narrow periodontal pocket bottom, and efficient driving is difficult to realize or a preparation process is tedious when an existing nano robot is used in the mouthwash. The mouthwash containing the swimming nano robot and used for active prevention and treatment of the oral cavity comprises a component A and a component B. The component A is composed of hydrogen peroxide, alcohol, glycerin, carboxymethyl cellulose, sodium lauryl sulfate and the balance ultrapure water. The component B is an aqueous solution containing the swimming nano robot. The mouthwash containing the moving nano robot and used for active prevention and treatment of the oral cavity is provided.

Description

technical field [0001] The invention relates to a mouthwash containing swimming nanorobots. Background technique [0002] Periodontal disease is an inflammatory disease caused by the accumulation of bacterial plaque. If it is not controlled, it will lead to loss of gingival attachment, periodontal pocket formation, alveolar bone resorption, and eventually loosening or even loss of teeth. Periodontal disease has become the main cause of adult tooth loss, seriously affecting people's health and quality of life. At present, toothpaste and mouthwash are the most frequently used when people clean their mouths in daily life. In recent years, the consumption of mouthwash among the population has been increasing, and the frequency of use is also increasing year by year. However, at present, most of the pathogenic bacteria are located in the periodontal pocket or in the deep part of the gums. The existing mouthwash cannot effectively penetrate and remove the bacteria, and the antiba...

Claims

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Application Information

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IPC IPC(8): A61K8/22A61K8/34A61K8/73A61K8/46A61K8/66A61K8/19A61K8/43A61K8/25A61K8/90A61K8/81A61Q11/00A61P1/02B82Y40/00B82Y5/00
CPCA61K8/22A61K8/34A61K8/345A61K8/731A61K8/463A61K8/66A61K8/19A61K8/43A61K8/25A61K8/8129A61K8/90A61Q11/00A61P1/02B82Y40/00B82Y5/00A61K2800/805A61K2800/56Y02A50/30
Inventor 贺强吴英杰
Owner HARBIN INST OF TECH
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