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In-vivo absorbable metal anastomosis nail and preparation method thereof

A staple and metal technology, which is applied in the field of absorbable metal staples in vivo and their preparation, can solve the problems of reducing the biocompatibility and safety of the device, inflammatory reaction of surrounding tissues, and slowly releasing debris, etc., so as to avoid premature Ineffectiveness, good biocompatibility, reduced degradation rate

Active Publication Date: 2021-10-22
THE SIXTH AFFILIATED HOSPITAL OF SUN YAT SEN UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The existing clinically used stainless steel or titanium and titanium alloy staples are not degradable, so the staples will permanently exist as foreign bodies in the human body, slowly releasing debris or even toxic and irritating ions, causing severe inflammation of the surrounding tissues Sexual reaction, reducing the biocompatibility and safety of the device; although the staples supported by magnesium and magnesium alloys can be degraded, there are problems such as too fast corrosion rate and insufficient mechanical strength

Method used

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  • In-vivo absorbable metal anastomosis nail and preparation method thereof
  • In-vivo absorbable metal anastomosis nail and preparation method thereof
  • In-vivo absorbable metal anastomosis nail and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] combine figure 1 As shown, an in vivo absorbable metal stapler includes a U-shaped body 1; the U-shaped body 1 is provided with a plurality of evenly arranged through grooves 2, and the inner wall of the U-shaped body 1 is provided with a plurality of locking grooves 3 , the locking slot 3 and the through slot 2 are staggered;

[0035] The surface of the U-shaped body 1 is provided with a coating 4 with corrosion resistance and excellent biocompatibility;

[0036] The staple is made of a U-shaped body 1 made of magnesium alloy and a coating 4 made of zinc alloy; the U-shaped body 1 is composed of the following raw materials by weight: 3.5% Zn, 0.415% Ca , 0.35Fe, 3.15%Mn, 0.1% rare earth, the balance is Mg;

[0037] The plating layer 4 is composed of the following raw materials in parts by weight: 0.0955% Mg, 0.75045% Ca, 1.0043% Cu, and the rest is Zn.

[0038] In this embodiment, the preparation method of the in vivo absorbable metal staples, the steps are as follo...

Embodiment 2

[0046] combine figure 1 As shown, an in vivo absorbable metal stapler includes a U-shaped body 1; the U-shaped body 1 is provided with a plurality of evenly arranged through grooves 2, and the inner wall of the U-shaped body 1 is provided with a plurality of locking grooves 3 , the locking slot 3 and the through slot 2 are staggered;

[0047]The surface of the U-shaped body 1 is provided with a coating 4 with corrosion resistance and excellent biocompatibility;

[0048] The staple is made of a U-shaped body 1 made of magnesium alloy and a coating 4 made of zinc alloy; the U-shaped body 1 is composed of the following raw materials by weight: 1.8% Zn, 0.18% Ca , 0.25% Fe, 3.6% Mn, 0.15% rare earth, and the balance is Mg;

[0049] The plating layer 4 is composed of the following raw materials by weight: 0.001% Mg, 0.0009% Ca, 2% Cu, and the rest is Zn.

[0050] In this embodiment, the preparation method of the in vivo absorbable metal staples, the steps are as follows:

[005...

Embodiment 3

[0058] combine figure 1 As shown, an in vivo absorbable metal stapler includes a U-shaped body 1; the U-shaped body 1 is provided with a plurality of evenly arranged through grooves 2, and the inner wall of the U-shaped body 1 is provided with a plurality of locking grooves 3 , the locking slot 3 and the through slot 2 are staggered;

[0059] The surface of the U-shaped body 1 is provided with a coating 4 with corrosion resistance and excellent biocompatibility;

[0060] The staple is made of a U-shaped body 1 made of magnesium alloy and a coating 4 made of zinc alloy; the U-shaped body 1 is composed of the following raw materials by weight: 5.2% Zn, 0.65% Ca , ~0.42% Fe, 2.7% Mn, 0.05% rare earth, and the balance is Mg;

[0061] The plating layer 4 is composed of the following raw materials in parts by weight: 0.19% Mg, 1.5% Ca, 0.0085% Cu, and the rest is Zn.

[0062] In this embodiment, the preparation method of the in vivo absorbable metal staples, the steps are as foll...

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Abstract

The invention relates to the related technical field of medical instruments, and more particularly discloses an in-vivo absorbable metal anastomosis nail. The in-vivo absorbable metal anastomosis nail comprises a U-shaped body, wherein a through groove is formed in the U-shaped body, and a plurality of locking grooves are formed in the inner wall of the U-shaped body; a plating coating is arranged on the surface of the U-shaped body; the anastomosis nail is prepared from the U-shaped body made of magnesium alloy and the plating coating made of zinc alloy; the U-shaped body is prepared from the following raw materials in parts by weight: Zn, Ca, Fe, Mn, rare earth and the balance of Mg; and the plating coating is prepared from the following raw materials in parts by weight: Mg, Ca, Cu and the balance of Zn. The invention further provides a preparation method of the anastomosis nail. The anastomosis nail prepared by the embodiment of the invention has the characteristics of relatively high corrosion resistance, better tensile strength, good improvement of degradation speed and the like under the combined action of the arrangement of the plating coating and the improvement of the structure of the U-shaped body, and the pain of a patient caused by a secondary operation is effectively avoided.

Description

technical field [0001] The invention relates to the related technical field of medical devices, more particularly, to an in vivo absorbable metal staple and a preparation method thereof. Background technique [0002] The stapler is a medical device that replaces manual suture. It is fast and easy to suture during surgery. It can significantly shorten the tissue exposure time, reduce trauma and bleeding, and effectively reduce surgical complications. Similar to a stapler, the tissue is separated. break or anastomosis. According to the different scope of application, it can be mainly divided into skin stapler, digestive tract (esophagus, gastrointestinal, etc.) circular stapler, rectal stapler, circular hemorrhoid stapler, circumcision stapler, vascular stapler, hernia stapler , Lung cutting stapler, etc. [0003] The staple materials currently used in clinical practice mainly include stainless steel, titanium and titanium alloys, and magnesium and magnesium alloys. [0004...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C22C23/04C22C23/00C22C18/02C22C18/00C22C1/02C22F1/06C23C2/06C23C2/34C21D9/52C21D9/00A61B17/064
CPCC22C23/04C22C23/00C22C18/00C22C18/02C22C1/02C22F1/06C21D9/0068C22F1/002C21D9/525C23C2/34C23C2/06A61B17/064A61B2017/00004
Inventor 林宏城马年方陈华显刘智敏李锦荣
Owner THE SIXTH AFFILIATED HOSPITAL OF SUN YAT SEN UNIV
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