Traditional Chinese medicine eye fumigation preparation, preparation method and application thereof

Abstract

The invention discloses a traditional Chinese medicine eye fumigation preparation, a preparation method and application thereof. The preparation method comprises the following steps: mixing mint and schizonepeta powder, and extracting by a distillation method to obtain volatile oil and a water-soluble part extracting solution 1; mixing the powdery divaricate saposhnikovia root, dandelion, honeysuckle flower, mulberry leaf and cicada slough, adding into water, and decocting to obtain an extracting solution 2; combining extracting solutions 1 and 2 to obtain a water-soluble total extracting solution 3; adding borneol into the boiled extracting solution 3, dissolving, and filtering while hot to obtain an extracting solution 4; sealing and standing the extracting solution 4 in a dark and cool place for 20-28 hours, and filtering again to obtain filtrate; and adding the volatile oil into the filtrate, adding pure water for quantification, adjusting the pH value to 6-8, uniformly mixing, hermetically boiling, and packaging to obtain the traditional Chinese medicine eye fumigation preparation. The preparation method is simple, the medicinal materials are common and easy to purchase, and the traditional Chinese medicine eye fumigation preparation has a remarkable curative effect on ocular surface diseases including xerophthalmia, meibomian gland dysfunction, conjunctivitis and keratitis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine development, and in particular relates to a traditional Chinese medicine smoked eye preparation and a preparation method and application thereof. Background technique [0002] The eye is a relatively fragile organ of the human body. According to statistics, ophthalmic preparation solution eye drops account for more than 60%. Because of its convenient use, easy formulation and good compliance, it is easily accepted by the majority of patients. Through the in-depth study of kinetics, it was found that conventional eye drops have problems such as short retention time of eye drugs and low bioavailability, and only less than 5% of the drugs reach the eye through the cornea to play a role, which greatly affects the efficiency of eye drug delivery. treatment effect. [0003] The application of traditional Chinese medicine in ophthalmology is unique and recuperative. Jinniu eye medic...

AI Technical Summary

Problems solved by technology

[0002] The eye is a relatively fragile organ of the human body. According to statistics, ophthalmic preparation solution eye drops account for more than 60%. Because of its convenient use, easy formulation and good compliance, it is easily accepted by the majority of patients. Through the in-depth study of kinetics, it was found that conventional eye drops have problems such as short retention time of eye drugs and low bioavailability, and only less than 5% of the drugs reach the eye through the cornea to play a role, which greatly affects the efficiency of eye drug delivery. treatment effect

[0003] The application of traditional Chinese medicine in ophthalmology is unique and recuperative. Jinniu eye medicine is a famous traditional Chinese medicine prescription. Powder, when using, use a small glass rod dipped in the powder and apply it to the eyes, which is inconvenient to use and has poor compliance

Chinese patent CN101579393A discloses a traditional Chinese medicine ophthalmic preparation and its preparation process, which mentions that the gel matrix includes hydroxypropylmethyl cellulose, sodium carboxymethyl cellulose, methyl cellulose, ethyl cellulose, carbomer , according to relevant data records and related experiments, the sodium carboxymethyl cellulose, hydroxypropyl methyl cellulose and calamine in the ophthalmic gel matrix have incompatibility, and the amount of methyl cellulose and ethyl cellulose Too high, the use effect is poor

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