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Fish oil or algal oil loaded microcapsule as well as preparation method and application thereof

A technology of microcapsules and algae oil, which is applied in application, food forming, food science, etc., can solve the problems of difficult control of reaction conditions, difficult preparation of liposomes, and low product load, so as to avoid oxidation and diffusion, and adapt to the Effects on promotion and application, extensive promotion and application

Pending Publication Date: 2020-12-22
NAT INST FOR NUTRITION & HEALTH CHINESE CENT FOR DISEASE CONTROL & PREVENTION +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, the methods for microencapsulation of fish oil or algae oil mainly include spray drying method, composite coacervation method, molecular embedding method, freeze drying method, orifice coagulation bath method and liposome embedding method. The preparation methods have their own advantages and disadvantages: the microcapsules prepared by the spray drying method have high purity, good dispersibility, high solubility, low cost, and are easy to transport and store, but there are shortcomings such as uneven particle size, partial depression or even rupture ; Although the preparation process of the composite coacervation method has mild conditions, it has the characteristics of high yield, high efficiency and little impact on the biological activity of the non-water-soluble core material, but the reaction conditions are difficult to control, and the reaction system must be controlled in a dilute solution, and the cost is high; The molecular embedding method is simple to prepare and does not require special equipment. The microcapsule product is not easy to absorb moisture and agglomerate, and can be stored for a long time, but the product load is low, and the droplet size of the core material is required to be certain; the liposome embedding method can control the The release speed of the embedded functional components is good, and the dispersion in water is good, but the preparation of liposomes is difficult, and the products often have disadvantages such as large particle size, poor stability, and residual toxic and harmful solvents
[0007] For example CN103549442A discloses a kind of DHA algae oil microcapsule powder of high oil loading and its preparation process, described preparation process comprises: earlier the outer wall material and emulsifier are dissolved and emulsified and sheared to make pre-emulsion, then add The core material and antioxidants are emulsified and sheared to obtain the final emulsion, and finally spray-dried to obtain DHA algae oil microcapsule powder. The preparation process adopts a spray-drying method, and there are problems of uneven product particle size, partial depression or even rupture. Insufficient, and added a large amount of emulsifier composed of one or more of sodium tyrosine, monoglyceride and sucrose fatty acid ester, resulting in increased cost input
[0008] CN105533691A discloses a novel micro-nano-scale fish oil / algae oil microcapsule and its preparation process. The preparation process includes the preparation of internal oil phase, water phase preparation, external oil phase preparation, preparation of calcium chloride curing agent, chitosan The preparation of the solution, the first rapid membrane emulsification, the second rapid membrane emulsification, the solidification of calcium chloride, the coagulation of the complex, and freeze-drying. The preparation process adopts the freeze-drying method, which is not only complicated in process, but also consumes a lot of energy

Method used

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  • Fish oil or algal oil loaded microcapsule as well as preparation method and application thereof
  • Fish oil or algal oil loaded microcapsule as well as preparation method and application thereof
  • Fish oil or algal oil loaded microcapsule as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] This embodiment provides a method for preparing microcapsules loaded with fish oil or algae oil, said preparation method comprising the following steps:

[0061] (1) Set the target mass ratio of sodium alginate, gelatin and glucose (protective agent) to 6:1:1, take 0.3g sodium alginate and dissolve it in 10mL deionized water, take 0.05g glucose and 0.05g gelatin and dissolve it in 10mL deionized water, mix the two evenly to obtain a wall material solution; wherein, the concentration of sodium alginate in the wall material solution is 1.5g / mL;

[0062] (2) According to the target oil loading of 30%, add 0.12g fish oil to the wall material solution described in step (1) and use ultrasonic emulsification treatment to mix evenly to obtain the wall core material mixed emulsion; wherein, the ultrasonic emulsification treatment The ultrasonic power is 200W, the ultrasonic program is super 2s and stop 2s, and the ultrasonic time is 1min;

[0063] (3) the wall core material mix...

Embodiment 2

[0066] This example provides a method for preparing microcapsules loaded with fish oil or algae oil, except that the "glucose" in step (1) is replaced with "sucrose", and the other conditions are exactly the same as in Example 1.

Embodiment 3

[0068] This example provides a method for preparing microcapsules loaded with fish oil or algae oil, except that the amount of fish oil added in step (2) is replaced by "0.12g" to "0.20g", that is, the target oil load is changed from "30% " is replaced by " 50% ", and other conditions are identical with embodiment 1.

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PUM

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Abstract

The invention relates to a fish oil or algal oil loaded microcapsule and a preparation method and application thereof, the fish oil or algal oil loaded microcapsule comprises a wall material for embedding fish oil or algal oil, the wall material comprises calcium alginate, gelatin and a protective agent, and the preparation method comprises the following steps: dissolving sodium alginate, gelatinand the protective agent in deionized water according to a target mass ratio of (5-7): (1-2): (1-2); preparing the fish oil or algae oil loaded microcapsule by combining a spray drying method and an ion curing method, and the fish oil or algae oil loaded microcapsule can be used for preparing food or health care products. The wall material of the fish oil or algae oil loaded microcapsule can isolate the fish oil or algae oil from oxygen, light, heat and other environmental factors, and has the advantages of low price, easiness in obtaining, health care effect, low production cost and suitability for wide popularization and application; the fish oil or algal oil loaded microcapsule prepared by the preparation method disclosed by the invention not only is regular in sphere, but also has theadvantages of uniform particle size distribution and particle size of 30-70 microns.

Description

technical field [0001] The invention relates to the technical field of microencapsulation, in particular to a microcapsule loaded with fish oil or algae oil, a preparation method and application thereof. Background technique [0002] Fish oil or algae oil is rich in various n-3 polyunsaturated fatty acids (n-3PUFA) such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are necessary for the human body. EPA is known as "vascular scavenger", which has the functions of dredging and cleaning the cardiovascular system, reducing serum cholesterol and low-density lipoprotein levels in the human body, improving high blood pressure, and preventing arteriosclerosis and other diseases. DHA is called "brain gold". It has the function of assisting the development of brain cells, can maintain the normal physiological activities of nerve cells, participate in the formation of brain thinking and memory, and is closely related to brain health. It also has anti-aging and im...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/115A23L33/16A23L29/256A23L29/281A23P10/30
CPCA23L33/115A23L33/16A23L29/256A23L29/284A23P10/30A23V2002/00
Inventor 丁钢强霍军生王连艳黄建张贵锋唐艳斌曹科崔迎彬曹政
Owner NAT INST FOR NUTRITION & HEALTH CHINESE CENT FOR DISEASE CONTROL & PREVENTION
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