A kind of citrus peel flavonoid gel ball and its preparation method and application
A technology of peel flavonoid gel balls and grapefruit peel flavonoids, which are applied in the field of peel flavonoid gel balls and preparation thereof, can solve the problems that peel flavonoids cannot be directly dissolved in water, etc., and achieve good fixed-point release characteristics and stability. good effect
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Embodiment 1
[0075] The present embodiment provides a kind of preparation method of grapefruit peel flavonoid gel ball, which is specifically as follows:
[0076] 1) Preparation of flavonoid core material emulsion: first, the peel of grapefruit is made into rough powder of peeled flavonoids, and then the crude extract of flavonoids from peel of grapefruit is added in a proportion of 2% of ethyl oleate and an emulsifier. In the mixed solution of polyoxyethylene hydrogenated castor oil and polyethylene glycol, fully mix until uniform to obtain flavonoid core material emulsion;
[0077] Among them, the volume ratio of ethyl oleate, polyoxyethylene hydrogenated castor oil and polyethylene glycol is 35:3:2; [oil phase (ethyl oleate) and emulsifier (polyoxyethylene hydrogenated castor oil and The volume ratio of ethylene glycol) is 7:1]
[0078] 2) Preparation of flavonoid sodium alginate core wall material mixture: under the condition of high-speed shearing at a rotational speed of 14,000 rpm,...
Embodiment 2~3
[0082] The present embodiment provides a preparation method of grapefruit peel flavonoid gel balls, the only difference from Example 1 is: in step 1), the co-emulsifier "polyethylene glycol" is replaced with "glycerol" or "1" , 2 Propylene Glycol".
[0083] During the experiment, Zetasiz laser particle sizer was used to measure particle size, polydispersity, and potential.
[0084] Taking ethyl oleate as oil phase and polyoxyethylene hydrogenated castor oil as emulsifier, the particle size of the emulsion after the treatment is smaller, and the polydispersed system numerical value is smaller (polyoxyethylene hydrogenated castor oil PdI 0.70, Tween 80 (polyethylene glycol) Diol) PdI 0.87, the smaller the PdI, the better the stability), the greater the absolute value of the potential (polyoxyethylene hydrogenated castor oil potential value -27.6, Tween 80 potential value -16.5, the greater the potential absolute value, the better the stability. it is good).
[0085]On the basi...
Embodiment 4~9
[0087] This embodiment provides a preparation method of grapefruit peel flavonoid gel ball, the difference from Example 1 is only in: "oil phase (ethyl oleate) and emulsifier (polyoxyethylene hydrogenated castor oil and polyethylene glycol) ) is 7:1" with "6:1", "5:1", "4:1", "2:1" or "8:1".
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