Composition, vaginal gel prepared from composition and application of composition in resisting human papilloma viruses

Abstract

The invention discloses a composition, vaginal gel prepared from the composition and application of the composition in resisting human papilloma viruses. The gel comprises the effective components ofbeta-glucan and hyaluronic acid, and the beta-glucan and hyaluronic acid are both carriers of gel products and are anti-human papilloma virus functional components of the gel products. And moreover, the the beta-glucan and hyaluronic acid have quite high biocompatibility and almost have no toxic or side effect. The beta-glucan and hyaluronic acid have the effect of synergistically resisting humanpapilloma viruses, and have the advantages of being stable, moderate in viscosity, comfortable to use and free of influence on vaginal bacteria.

Description

technical field [0001] The invention relates to the technical field of gynecological care products, in particular to a vaginal gel anti-human papillomavirus product. Background technique [0002] High-risk HPV infection can easily lead to cervical intraepithelial neoplasia and cervical cancer. Effective intervention in the early stage of HPV infection is of great significance to improve the prognosis. Among them, the long-term infection of HPV16 and HPV18 subtypes has been proved to be a major cause of cervical cancer. At present, there is no specific preventive drug against HPV on the market, and the HPV vaccine is mainly suitable for women who have not had sexual activity. Therefore, it is of great significance to develop new anti-HPV health care products and medicines. Interferon commonly used in drug treatment of cervical HPV infection, such as Xinfuning (recombinant human interferon ɑ2b vaginal effervescent capsule), theoretically induces the production of antiviral p...

AI Technical Summary

Problems solved by technology

[0007] The anti-HPV products containing β-glucan in the prior art have insufficient effect on removing HPV; and hormones and interferons (such as recombinant human interferon α-2b) are added on the basis of β-glucan , extracts or chemically synthesized drugs, etc., on the one hand, there are safety hazards and side effects, which affect the beneficial bacteria in the vagina; on the other hand, for anti-HPV gel products containing β-glucan, the added Substances are unfavorable to the formation of gel dosage forms, and the physical and chemical properties of the additives need to be considered, and the stability is relatively poor; making the process of preparing gel dosage forms relatively complicated

Images