A kind of high-strength waterproof breathable composite dressing and preparation method thereof

A waterproof, breathable, high-strength technology, used in dressings, non-adhesive dressings, bandages, etc., can solve the problems of affecting the ventilation effect, the difficulty of combining PTFE and hydrogel, and achieve the prevention of wound infection, excellent ability to absorb exudate , pain relief effect

Active Publication Date: 2021-10-08
SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of the above-mentioned deficiencies in the prior art, the purpose of the present invention is to provide a high-strength waterproof and breathable composite dressing to solve the problem of using a tackifier to connect polytetrafluoroethylene and hydrogel to affect its breathability in the prior art. question
[0006] The present invention also provides the method for preparing this composite dressing, to solve the technical problem that polytetrafluoroethylene is difficult to combine with hydrogel

Method used

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  • A kind of high-strength waterproof breathable composite dressing and preparation method thereof
  • A kind of high-strength waterproof breathable composite dressing and preparation method thereof
  • A kind of high-strength waterproof breathable composite dressing and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0045] Embodiment 1: the composite of expanded polytetrafluoroethylene and PVA hydrogel

[0046] (1) Activation: Select an uncoated double-stretched expanded polytetrafluoroethylene film with a pore size of 0.1 microns and a thickness of 150 microns, cut the film into a square of 10cmx10cm; fix the expanded polytetrafluoroethylene film on a flat glass, put Into the 20MHz vacuum plasma generation chamber; evacuate and feed the argon gas at a flow rate of 20mL / min, adjust the equipment power to 115w, control the vacuum degree of the system to 0.095MPa, and conduct plasma treatment for 100s.

[0047] (2) Grafting: Immediately transfer the film to a special mold, add 1mol / L vinylpyrrolidone aqueous solution, and pass through nitrogen to remove oxygen, then transfer to a UV lamp for irradiation and grafting for 6 hours.

[0048] (3) Cleaning: Immerse the membrane in deionized water and change the water every 8 hours for a total of 24 hours.

[0049] (4) Composite: Transfer the cle...

Embodiment 2

[0052] Embodiment 2: Composite of expanded polytetrafluoroethylene and hydroxyethyl methacrylate hydrogel

[0053] In Example 2, the pretreatment method of the expanded polytetrafluoroethylene membrane is the same as that of Example 1, except that the preparation of the hydrogel, that is, the step (4) is different.

[0054] (4) Composite: The plasma-activated and PVP-grafted basement membrane was transferred to the hydrogel preparation fixture. Prepare a hydroxyethyl methacrylate solution with a concentration of 1mol / L, and add a crosslinking agent N,N-methylenebisacrylamide (concentration of 1 mol% of the monomer concentration) and an initiator α-pentyl Diacid (0.1 mol% of monomer concentration). Nitrogen was passed through the above solution to remove oxygen, and transferred to a mold with a base film, and irradiated under 365nm ultraviolet light for 12h. Take it out and soak it in deionized water for 24 h, and change the deionized water three times during this period to p...

Embodiment 3

[0056] Embodiment 3: Composite of expanded polytetrafluoroethylene and polymethacrylic acid hydrogel

[0057] In Example 3, the pretreatment method of the expanded polytetrafluoroethylene membrane is the same as that of Example 1, except that the preparation of the hydrogel, that is, step (4) is different.

[0058] (4) Composite: The plasma-activated and PVP-grafted basement membrane was transferred to the hydrogel preparation fixture. Prepare a methacrylic acid solution with a concentration of 1 mol / L, and add the initiator α-glutaric acid (0.1 mol% of the monomer concentration) into it. Nitrogen was passed through the above solution to remove oxygen, and transferred to a mold with a base film, and irradiated under 365 nm ultraviolet light for 12 hours. Take it out and soak it in deionized water for 24 h, and change the deionized water three times during this period to prepare a composite hydrogel.

[0059] (5) Post-processing: Coating polyacrylate pressure-sensitive adhesi...

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Abstract

The invention discloses a high-strength waterproof and breathable composite dressing and a preparation method thereof, comprising an outer layer and an inner layer, the outer layer is a polytetrafluoroethylene film, the inner layer is a hydrogel, and the polytetrafluoroethylene film has a channel structure , the polytetrafluoroethylene film is compositely connected with the inner hydrogel by grafting a hydrophilic polymer compound. The composite dressing prepared by the present invention uses expanded polytetrafluoroethylene film as the outer layer structure, so that the dressing has good waterproof and antifouling properties, and its special pore structure can effectively prevent bacteria from penetrating into the wound and effectively prevent wound infection; at the same time, Wound exudate and sweat on the skin can also evaporate quickly through this special pore structure. This composite dressing retains the excellent properties of expanded polytetrafluoroethylene, making the dressing meet the needs of wound treatment under complex conditions on the battlefield and in the field.

Description

technical field [0001] The invention relates to the technical field of medical dressings, in particular to a high-strength waterproof and breathable composite dressing and a preparation method thereof. Background technique [0002] Traditional surgery uses gauze to cover the wound, but the gauze needs to be changed every few hours until the wound scabs over. The yarn is easy to adhere to the wound, and it is easy to cause secondary damage to the wound when it is replaced, forming a chronic wound, delaying healing, and even threatening life. For this reason, modern medicine has developed a hydrogel dressing to directly cover the wound. Its inner layer is often a hydrogel that can promote wound healing and can be directly bonded to the skin, and its outer layer is a non-woven fabric or polyurethane cloth. It has good air permeability, but this material is poorly waterproof, and it does not have the ability to isolate bacteria. [0003] For battlefields, fields and other occa...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F13/00A61L15/20A61L15/24A61L15/26A61L15/42A61L15/46A61L15/52
CPCA61F13/00017A61F13/00029A61F13/00046A61F13/00987A61F2013/00187A61F2013/00246A61F2013/00319A61F2013/00727A61L15/20A61L15/24A61L15/26A61L15/42A61L15/425A61L15/46A61L15/52A61L2300/404A61L2300/412C08L27/18C08L39/06C08L29/04C08L33/02C08L71/02C08L33/26
Inventor 郑汶江邹伟陈骞杨帆刘波杨虎颜杰
Owner SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING
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