Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Dendrobium polysaccharide extract, and preparation method thereof

A technology for dendrobium polysaccharide and extract is applied in the field of dendrobium polysaccharide extract and its preparation, which can solve the problems of undisclosed yield of dendrobium polysaccharide, high safety requirements, complicated process operation, etc. The effect of large processing capacity

Inactive Publication Date: 2019-08-23
广州泽力医药科技有限公司
View PDF2 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the traditional plant polysaccharide extraction technology, mainly water extraction and alcohol precipitation method, microwave method, ultrasonic assisted water extraction method, supercritical fluid extraction method, etc., all of the above methods have the defects of low extraction efficiency and low yield of Dendrobium polysaccharides, usually Dendrobium polysaccharide extraction rate is not higher than 30%, and the process is complicated
[0004] Another method is to use low-temperature ultra-high pressure (UHP) technology to extract polysaccharides from Dendrobium. Under the conditions of low temperature below 20°C and ultra-high pressure of 450-550 MPa, the extraction rate of polysaccharides from Dendrobium can be improved by statically pressurized blasting of Dendrobium candidum plant cells to 95%, but this extraction method cannot obtain a certain purity of Dendrobium polysaccharides in the extraction process, and the yield of Dendrobium polysaccharides has not been disclosed, and the ultra-high pressure of low-temperature ultra-high pressure (UHP) technology requires high equipment safety , usually can only be used for laboratory research, it is difficult to be applied in large-scale industrial production

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Dendrobium polysaccharide extract, and preparation method thereof
  • Dendrobium polysaccharide extract, and preparation method thereof
  • Dendrobium polysaccharide extract, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] This embodiment is a preparation method of Dendrobium polysaccharide extract, the steps are as follows (process flow chart see figure 1 ):

[0038] 1. cut into strips: fresh dendrobium stem (its microscope image is as figure 2 shown) cut into small pieces between 0.5cm and 2cm;

[0039] 2. Pulverization: Use a high-efficiency turbo pulverizer with a pore size of 0.8mm to pulverize the fresh dendrobium stem segments into a fine pulp by adding a certain amount of purified water;

[0040] 3. Mixing and pulping: put the crushed fresh Dendrobium finely crushed pulp and purified water in the mixing tank of the high-speed mixer, stir and mix evenly and control the temperature not to exceed 25°C;

[0041] 4. Extraction: Add the mixed solution into the buffer tank of the high pressure difference continuous extractor, control the extraction force range to 25-35MPa, and extract the temperature at 20°C; collect the discharge to obtain the mixed material liquid; the high pressure...

Embodiment 2

[0051] This example is a preparation method of Dendrobium polysaccharide extract, the steps of which are the same as Example 1, the only difference is that in Step 4, the extraction pressure difference is controlled to be 10-20 MPa, and the extraction temperature is 35°C.

[0052] Specific steps are as follows:

[0053] 1. Cut into strips: Cut the fresh Dendrobium stems into small sections between 0.5cm and 2cm with a traditional Chinese medicine slicer;

[0054] 2. Pulverization: Use a high-efficiency turbo pulverizer with a pore size of 0.8mm to pulverize the fresh dendrobium stem segments into a fine pulp by adding a certain amount of purified water;

[0055] 3. Mixing and pulping: put the crushed fresh Dendrobium finely crushed pulp and purified water in the mixing tank of the high-speed mixer, stir and mix evenly and control the temperature not to exceed 25°C;

[0056] 4. Extraction: Add the mixed solution into the buffer tank of the high-pressure differential continuous...

Embodiment 3

[0065] This example is a preparation method of Dendrobium polysaccharide extract, the steps of which are the same as those of Example 1, the only difference is that in Step 4, the extraction pressure difference is controlled to be 40-50 MPa, and the extraction temperature is 15°C.

[0066] Specific steps are as follows:

[0067] 1. Cut into strips: Cut the fresh Dendrobium stems into small sections between 0.5cm and 2cm with a traditional Chinese medicine slicer;

[0068] 2. Pulverization: Use a high-efficiency turbo pulverizer with a pore size of 0.8mm to pulverize the fresh dendrobium stem segments into a fine pulp by adding a certain amount of purified water;

[0069] 3. Mixing and pulping: put the crushed fresh Dendrobium finely crushed pulp and purified water in the mixing tank of the high-speed mixer, stir and mix evenly and control the temperature not to exceed 25°C;

[0070] 4. Extraction: Add the mixed solution into the buffer tank of the high-pressure differential c...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Apertureaaaaaaaaaa
Apertureaaaaaaaaaa
Login to View More

Abstract

The invention relates to a dendrobium polysaccharide extract, and a preparation method thereof. The preparation method comprises following steps: 1, pretreatment, wherein dendrobium raw material is prepared, and is crushed so as to obtain a raw material powder; 2, extraction, wherein the raw material powder is added into water so as to obtain a pre-mixed solution, the pre-mixed solution is subjected to high differential pressure continuous extraction, an obtained extracted solution is collected, the extraction pressure of high differential pressure continuous extraction is controlled to be -0.1 to 50MPa; 3, separation, wherein the extracted solution is subjected to centrifugation, an obtained supernatant is collected and is subjected to microfiltration so as to obtain a microfiltered clearliquid; and 4, condensation, wherein the microfiltered clear liquid is subjected to condensation so as to obtain the dendrobium polysaccharide extract. The preparation method is capable of increasingdendrobium polysaccharide yield with ensured dendrobium extraction efficiency, and is capable of realizing industrialized continous large scale production.

Description

technical field [0001] The invention relates to the technical field of plant component extraction, in particular to a dendrobium polysaccharide extract and a preparation method thereof. Background technique [0002] Dendrobium officinale contains polysaccharides, alkaloids, proteins, flavonoids, 17 kinds of amino acids and 7 kinds of inorganic elements, the main active ingredient of which is Dendrobium polysaccharides. Modern pharmacological studies have shown that Dendrobium polysaccharides have the effects of improving immunity, anti-tumor, anti-oxidation, lowering blood sugar, lowering blood pressure and anti-Sjogren's syndrome. Therefore, it is of great significance to study the development of extraction technology of Dendrobium officinale polysaccharides. [0003] In the traditional plant polysaccharide extraction technology, mainly water extraction and alcohol precipitation method, microwave method, ultrasonic assisted water extraction method, supercritical fluid extr...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C08B37/00
CPCC08B37/0003
Inventor 刘常青马志鹏宋力飞刘乡乡
Owner 广州泽力医药科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com