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Compound pellets containing multiple amino acids, vitamins and mineral substances and preparation method of compound pellets

A technology of compound pellets and vitamins, which is applied in the field of medicine and health food, can solve problems such as inability to ensure the uniformity of ingredients, achieve good market application prospects, improve stability, and avoid interaction effects

Inactive Publication Date: 2019-07-12
湖北省八峰药化股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to overcome the problem that the existing compound micropills contain few nutritional components, and the nutritional components such as amino acids and vitamins are separately prepared into pills, which cannot ensure the uniformity of each component in the final preparation.

Method used

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  • Compound pellets containing multiple amino acids, vitamins and mineral substances and preparation method of compound pellets
  • Compound pellets containing multiple amino acids, vitamins and mineral substances and preparation method of compound pellets
  • Compound pellets containing multiple amino acids, vitamins and mineral substances and preparation method of compound pellets

Examples

Experimental program
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Effect test

Embodiment approach

[0029] An optimized embodiment, the drug-coated coating is also wrapped with a layer of outer coating layer, the outer coating layer is a coating that is not easily dissolved in common water, and its main function is that the pellets are not easily broken in water for a short time (3 to 5 minutes). Dissolution is not only beneficial to moisture-proof, but also beneficial to the granules made of the pellets to form a suspension in water, the ingredients are not easy to dissolve, which plays an important role in improving the taste; Propyl cellulose, ethyl cellulose or direct purchase of commercially available coating powders, such as enhanced moisture-proof coating pre-powder, HPC water dispersion, EC water dispersion, etc.

[0030] Table 1: Characteristics and functions of amino acids

[0031]

[0032]

[0033]

[0034] Table 2: Vitamin properties and functions

[0035]

[0036]

[0037]

[0038]

[0039] Table 3: Common carriers and functions of human el...

Embodiment 1

[0044] The present embodiment provides a kind of compound micropill containing various amino acids, vitamins and minerals, and its prescription is as follows:

[0045] L-leucine 42mg, L-isoleucine 30mg, L-valine 30mg, L-lysine hydrochloride 45mg, L-threonine 21mg, L-methionine 39mg, L-tryptophan 10.5mg, L-phenylalanine 40mg, L-histidine hydrochloride 30mg, L-arginine 32mg, L-alanine 24mg, L-aspartic acid 16mg, L-cysteine ​​hydrochloride 4.5mg , L-glutamic acid 14mg, L-proline 7mg, L-tyrosine 2mg, glycine 22mg, L-serine 5mg, asparagine 12mg, glutamine 14mg;

[0046] Vitamin A (β-carotene) 625IU, thiamine hydrochloride (vitamin B1) 7.5mg, riboflavin (vitamin B2) 7.5mg, niacinamide (vitamin B3) 15mg, calcium pantothenate (vitamin B5) 10mg, pyridoxine hydrochloride Alcohol (vitamin B6) 7.5mg, biotin (vitamin B7) 0.5mg, folic acid (vitamin B9) 100mg, methylcobalamin (vitamin B12) 40mcg, calcium ascorbate (vitamin C) 30mg, cholecalciferol (vitamin D3) 65IU, d-α-tocopheryl succinat...

Embodiment 2

[0057] The present embodiment provides a kind of compound micropill containing various amino acids, vitamins and minerals, and its prescription is as follows:

[0058] L-leucine 42mg, L-isoleucine 30mg, L-valine 30mg, L-lysine hydrochloride 45mg, L-threonine 21mg, L-methionine 39mg, L-tryptophan 10.5mg, L-phenylalanine 40mg, L-histidine hydrochloride 30mg, L-arginine 32mg, L-alanine 24mg, L-aspartic acid 16mg, L-cysteine ​​hydrochloride 4.5mg , L-glutamic acid 14mg, L-proline 7mg, L-tyrosine 2mg, glycine 22mg, L-serine 5mg, asparagine 12mg, glutamine 14mg;

[0059] Vitamin A (β-carotene) 625IU, thiamine hydrochloride (vitamin B1) 7.5mg, riboflavin (vitamin B2) 7.5mg, niacinamide (vitamin B3) 15mg, calcium pantothenate (vitamin B5) 10mg, pyridoxine hydrochloride Alcohol (vitamin B6) 7.5mg, biotin (vitamin B7) 0.5mg, folic acid (vitamin B9) 100mg, methylcobalamin (vitamin B12) 40mcg, calcium ascorbate (vitamin C) 30mg, cholecalciferol (vitamin D3) 65IU, d-α-tocopheryl succinat...

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Abstract

The invention provides compound pellets containing multiple amino acids, vitamins and mineral substances. The compound pellets comprise pellet cores and medicine covering casings wrapping the pellet cores. Isolating layers are arranged between the pellet core and the medicine covering casings, the pellet cores comprise the vitamins, the mineral substances and accessories, the medicine covering casings are made from amino acid in a powder or suspension form, and the amino acid comprises leucine, isoleucine, valine, lysine, threonine, methionine, tryptophan and phenylalanine. According to the compound pellets, multiple amino acids, vitamins and mineral substances are gathered in the pellets, a complete whole is formed, the homogeneity is ensured, the amino acid is separated from the vitamins, the mineral substances and other ingredients through the isolating layers, interaction between different kinds of ingredients is avoided, the stability of the preparation is improved, the compound pellets can be used for auxiliary treatment of diseases caused by lack of the amino acid, the vitamins and the mineral substances and nutrition and health care of health restoration of after-disease and sub-health people, and the immunologic function of the human body can be enhanced.

Description

technical field [0001] The invention belongs to the technical field of medicine and health food, and in particular relates to a compound pellet containing various amino acids, vitamins and minerals and a preparation method thereof. Background technique [0002] Amino acid is the basic substance that constitutes the protein needed for human nutrition. It is a class of organic compounds containing basic amino groups and acidic carboxyl groups. Most of the amino acids that make up proteins are α-amino acids, and there are about 20 kinds. Amino acid is the basic unit of protein. It plays an important role in the human body through metabolism, such as synthesizing tissue protein, turning it into acid, hormone, antibody, creatine and other ammonia-containing substances, turning it into carbohydrates and fats, and oxidizing it into carbon dioxide and water. Urea, energy production, etc.; different amino acids have different physiological functions. When supplementing amino acids, t...

Claims

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Application Information

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IPC IPC(8): A61K33/32A61K9/50A61P39/00A61P37/04A61P3/02A23L33/15A23L33/155A23L33/16A23L33/175A23P10/30A61K31/07A61K31/14A61K31/197A61K31/198A61K31/355A61K31/375A61K31/401A61K31/405A61K31/4172A61K31/4188A61K31/4415A61K31/455A61K31/51A61K31/519A61K31/525A61K31/593A61K31/714A61K33/04A61K33/06A61K33/26A61K33/30
CPCA23V2002/00A61K9/5073A61K31/07A61K31/14A61K31/197A61K31/198A61K31/355A61K31/375A61K31/401A61K31/405A61K31/4172A61K31/4188A61K31/4415A61K31/455A61K31/51A61K31/519A61K31/525A61K31/593A61K31/714A61K33/04A61K33/06A61K33/26A61K33/30A61K33/32A23L33/15A23L33/155A23L33/16A23L33/175A23P10/30A61P3/02A61P37/04A61P39/00A61K2300/00A23V2250/0628A23V2250/0626A23V2250/0654A23V2250/063A23V2250/0648A23V2250/065A23V2250/0638A23V2250/0624A23V2250/0606A23V2250/0604A23V2250/061A23V2250/0616A23V2250/0618A23V2250/064A23V2250/0652A23V2250/0622A23V2250/0642A23V2250/0608A23V2250/062A23V2250/702A23V2250/7042A23V2250/7044A23V2250/7046A23V2250/705A23V2250/7052A23V2250/7054A23V2250/7058A23V2250/706A23V2250/708A23V2250/71A23V2250/712A23V2250/714A23V2250/304A23V2250/1642A23V2250/1578A23V2250/1592A23V2250/1626A23V2250/161A23V2250/1612
Inventor 程天贵汪大顺丁杰张红霞覃遵武
Owner 湖北省八峰药化股份有限公司
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