Pharmaceutical composition with effects of activating blood, removing stasis, reducing blood lipid and assisting in regulating cardiovascular and cerebrovascular diseases and preparation method thereof

Abstract

The invention discloses a pharmaceutical composition with effects of activating blood, removing stasis, reducing blood lipid and assisting in regulating cardiovascular and cerebrovascular diseases anda preparation method thereof. The pharmaceutical composition comprises raw materials in parts by weight as follows: 3-10 parts of a ginkgo leaf extract, 60-100 parts of kudzuvine root, 60-100 parts of danshen roots and 60-100 parts of poria cocos. The preparation method comprises the steps as follows: preparing and pretreating the kudzuvine root, the danshen roots and the poria cocos; adding thematerials to water for extraction and concentration to prepare a concentrated liquid; drying the concentrated liquid to obtain dry powder; and uniformly mixing the dry powder and the ginkgo leaf extract in ratio. The pharmaceutical composition is prepared into pills, ointment, sublimed preparation, tablets, capsules, oral liquid, powder and granules after the pharmaceutically acceptable salt. Allmedicines are combined in the formula, and the formula has effects of invigorating the spleen to eliminate dampness, tonifying the liver and kidney, reducing phlegm and removing blood stasis, has obvious effects of reducing blood lipid, has the total effective rate up to 86.27% and has no toxic or side effects.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical compositions, in particular to a pharmaceutical composition, preparation and preparation method for promoting blood circulation, removing blood stasis, lowering blood fat, and assisting in regulating cardiovascular and cerebrovascular diseases. Background technique [0002] With the aging of the society and the acceleration of urbanization, the unhealthy lifestyle of residents is popular, and the risk factors of cardiovascular disease in Chinese residents are generally exposed, showing a trend of rapid growth and individual aggregation among younger age and low-income groups. In the next 10 years, the number of patients with cardiovascular diseases will continue to increase rapidly, and it is estimated that the number of patients with cardiovascular diseases will reach 290 million. At present, the death of cardiovascular disease accounts for the first place in the total death of urban and r...

AI Technical Summary

Problems solved by technology

Moreover, currently known blood lipid-lowering drugs more or less affect liver function, have obvious toxic and side effects, and the cost is also very expensive.

[0005] For example, antihypertensive and lipid-lowering drugs represented by aspirin have the following deficiencies: (1) the main mechanism of action of aspirin is to inhibit the production of TXA2, anti-platelet aggregation, and thus play an antithrombotic effect

(3) There is dependence, long-term use will increase the risk of bleeding in patients, and it cannot regulate blood pressure in both directions, so it is not suitable for patients with hypotension

Other drugs have the following disadvantages in the treatment of hyperlipidemia: (1) The side effects are large, such as pantothenic acid, stomach discomfort, laxative and other side effects, and those with hyperacidity or ulcer disease should use it with caution

(2) It can cause liver damage, and some drugs can increase blood sugar

(3) It can only be controlled within the normal range and cannot be completely cured

Other non-pharmaceutical products using deep-sea fish oil, seal oil, and seal oil as the main raw materials also have the following disadvantages: (1) It comes from animal fat and is rich in cholesterol. Long-term intake will increase cholesterol in the human body and increase the risk of coronary heart disease

(3) Easy to oxidize, bad taste

(4) Low absorption rate, serious heavy metal pollution, especially mercury pollution

But there are also the following deficiencies: (1) The cost is high, generally tens of thousands of yuan a time, which is difficult for ordinary families to afford

(2) The risk is high, and the safety of plasma input is at risk

(3) The duration is short, and the index does not cure the root cause

It usually lasts for 3-10 months and cannot fundamentally solve the problem of cardiovascular and cerebrovascular diseases

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