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Method for promoting stability of fuke qianjin tablet

A technology of gynecological Qianjin tablet and Qianjinpu is applied in the fields of sexually transmitted diseases, scientific instruments, pharmaceutical formulations, etc., to achieve the effect of fast detection process and high accuracy

Inactive Publication Date: 2019-01-01
ZHUZHOU QIANJIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to overcome the above-mentioned deficiencies of the prior art and provide a method for improving the stability of Fukeqianjin Tablets. By clarifying and limiting the content of genistin and the total amount of andrographolide and dehydroandrographolide, it can effectively Improve the stability of Fukeqianjin Tablets, avoid the problem of poor therapeutic effect due to deliquescence or oxidation, and improve the clinical efficacy of Fukeqianjin Tablets

Method used

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  • Method for promoting stability of fuke qianjin tablet
  • Method for promoting stability of fuke qianjin tablet
  • Method for promoting stability of fuke qianjin tablet

Examples

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Effect test

Embodiment 1

[0033] Example 1 Fuke Qianjin Tablets

[0034] Prepare Fukeqianjin Tablets by the following method:

[0035] The formula of Fukeqianjin Tablets: Angelica, Codonopsis, Andrographis paniculata and Shuangmianzhen each account for 9% of the total amount of medicinal materials; the dosages of Rosa japonica root, Caulis Spatholobus, Gongluomu and Qianjinba each account for 16% of the total amount of medicinal materials.

[0036] 1. Select Angelica, Codonopsis, and Andrographis paniculata, crush them into fine powders of more than 100 meshes, and keep them for later use according to the powder yield of at least 93.3%;

[0037] 2. Select single-faced needle, golden cherry root, Caulis Spatholobus, Gonglaomu and Qianjinba, add water to extract twice, add water 12 times the total weight of the five-flavored traditional Chinese medicine for the first time, and add 10 times the total weight of the five-flavored traditional Chinese medicine for the second time water, each extraction time ...

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Abstract

The invention discloses a method for promoting stability of fuke qianjin tablet. The fuke qianjin tablet is prepared from the following raw materials: philippine flemingia root, Chinese mahonia stem,herba andrographitis, zanthoxylum dissitum hemsl, caulis spatholobi, angelica sinensis, codonopsis pilosula and Cherokee rose root. During the preparation process of the fuke qianjin tablet, the content of genistin and the total volume of andrographolide and dehydrated andrographolide are regulated; in each fuke qianjin tablet, the content of genistin is not less than 0.008mg and the total volumeof andrographolide and dehydrated andrographolide is not less than 1.1mg; HPLC method is optimally adopted for detecting the content. According to the invention, the important influences of the content of genistin and the total volume of andrographolide and dehydrated andrographolide in the fuke qianjin tablet on the product are confirmed and the accurate content thereof is limited. Compared withthe prior art, the product prepared according to the invention has the advantages that the stability is higher, deliquescence and oxidation are difficult to occur, the fuke qianjin tablet is suitablefor long-term storage and the clinical efficacy is further promoted.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a method for improving the stability of Fuke Qianjin Tablets. Background technique [0002] Fukeqianjin Tablets are medicines made from 8 medicinal materials, including Qianjinba, Rosa Radix, Andrographis paniculata, Gongluomu, Shuangmianzhen, Angelica, Millipede Spatholobus, and Codonopsis pilosula. The effect is to clear heat and dehumidify, tonify qi and blood. It is used for leukorrhea and abdominal pain caused by damp heat and blood stasis. Symptoms include profuse leukorrhagia, thick yellow matter, foul smell, lower abdomen pain, lumbosacral pain, mental fatigue and fatigue; chronic pelvic inflammatory disease, endometritis, Chronic cervicitis see the above syndrome. [0003] In the existing Chinese Pharmacopoeia, for the content identification of Fukeqianjin Tablets, only the total content of andrographolide and dehydroandrographolide is limited, sp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/758A61K9/20A61P15/00G01N30/02
CPCA61K9/20A61K36/19A61K36/232A61K36/29A61K36/344A61K36/48A61K36/486A61K36/738A61K36/758A61K2236/331A61K2236/39A61P15/00G01N30/02G01N2030/027A61K2300/00
Inventor 彭开锋龚云凌勇根白璐郑元青付卡利袁红波
Owner ZHUZHOU QIANJIN PHARMA
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