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Gingko drop pill and preparation method thereof

A technology of dropping pills and ginkgo, which is applied in the field of ginkgo dropping pills and its preparation, can solve the problems of ginkgo dropping pills, such as bitter taste, increased vascular fragility, and increased cerebral hemorrhage, so as to achieve improved bioavailability, increased purity, and uniform and sufficient heating Effect

Inactive Publication Date: 2018-11-27
ANHUI SONGSHANTANG CHINESE HERBAL MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although Ginkgo Leaf Pills have a good effect on promoting blood circulation and removing blood stasis, the active ingredients in them will increase the risk of cerebral hemorrhage. Although long-term use will not produce drug resistance like drugs, long-term use of Ginkgo Leaf Pills Will increase the fragility of blood vessels; in addition, the existing ginkgo dripping pills have a bitter taste, are difficult to swallow, and are not liked by consumers

Method used

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  • Gingko drop pill and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A ginkgo drop pill, made of the following components by weight: 180 parts of polyethylene glycol 4000, 15 parts of ginkgo leaf extract, 4.6 parts of walnut, 4.2 parts of salvia miltiorrhiza, 3.5 parts of sealwort, 2.6 parts of astragalus, and 2 parts of hawthorn , 3 parts of honey, 1.8 parts of shiitake mushrooms, 140 parts of simethicone oil, and 150 parts of castor oil.

[0026] Further, the preparation of the ginkgo extract comprises the following steps:

[0027] 1) Drying and crushing treatment: pick fresh ginkgo leaves and place them in a freeze-drying box for freeze-drying, and then put the dried ginkgo leaves in a cryogenic grinder for crushing;

[0028] 2) Ultrasonic treatment: put the ginkgo leaf powder obtained in operation 1) into a triangular flask, add 75% ethanol which is 7 times the weight of the ginkgo leaf powder, shake well, and place it in an ultrasonic wave of a specific wavelength for 7 minutes;

[0029] 3) Microwave-assisted extraction: put the Gi...

Embodiment 2

[0041] A ginkgo drop pill, made of the following components by weight: 190 parts of polyethylene glycol 4000, 20 parts of ginkgo leaf extract, 4.8 parts of walnut, 4.3 parts of salvia miltiorrhiza, 3.7 parts of sealwort, 2.7 parts of astragalus, and 2.5 parts of hawthorn , 3.5 parts of honey, 2 parts of shiitake mushrooms, 160 parts of simethicone oil, and 170 parts of castor oil.

[0042] Further, the preparation of the ginkgo extract comprises the following steps:

[0043] 1) Drying and crushing treatment: pick fresh ginkgo leaves and place them in a freeze-drying box for freeze-drying, and then put the dried ginkgo leaves in a cryogenic grinder for crushing;

[0044] 2) Ultrasonic treatment: put the ginkgo leaf powder obtained in operation 1) into a triangular flask, add 75% ethanol which is 7.5 times the weight of the ginkgo leaf powder, shake well, and place it in an ultrasonic wave of a specific wavelength for 8 minutes;

[0045] 3) Microwave assisted extraction: put th...

Embodiment 3

[0057] A ginkgo dropping pill and a preparation method thereof, which are made of the following components in parts by weight: 200 parts of polyethylene glycol 4000, 25 parts of ginkgo leaf extract, 5 parts of walnut, 4.4 parts of salvia miltiorrhiza, 3.9 parts of sealwort, 2.8 parts of astragalus , 3 parts of hawthorn, 4 parts of honey, 2.2 parts of shiitake mushrooms, 180 parts of simethicone oil, and 190 parts of castor oil.

[0058] Further, the preparation of the ginkgo extract comprises the following steps:

[0059] 1) Drying and crushing treatment: pick fresh ginkgo leaves and place them in a freeze-drying box for freeze-drying, and then put the dried ginkgo leaves in a cryogenic grinder for crushing;

[0060] 2) Ultrasonic treatment: put the ginkgo leaf powder obtained in operation 1) into a triangular flask, add 75% ethanol which is 8 times the weight of the ginkgo leaf powder, shake well, and place it in ultrasonic waves of a specific wavelength for 9 minutes;

[00...

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Abstract

The invention discloses a gingko drop pill and a preparation method thereof and belongs to the technical field of gingko drop pill preparation. The gingko drop pill is prepared from the following components in parts by weight: 180-200 parts of polyethylene glycol 4000, 15-25 parts of ginkgo biloba extract, 4.6-5 parts of walnut, 4.2-4.4 parts of salvia miltiorrhiza, 3.5-3.9 parts of sealwort, 2.6-2.8 parts of radix astragali, 2-3 parts of hawthorn, 3-4 parts of honey, 1.8-2.2 parts of mushroom, 140-180 parts of simethicone and 150-190 parts of castor oil. The gingko drop pill prepared according to the invention is capable of preventing and treating cardiovascular and cerebrovascular diseases, eliminating free radicals and delaying aging, has high activities and stable performance, almost has no toxic side effect, has high bioavailability, tastes nice, can be easily accepted by the public and has ultrahigh marketing value.

Description

technical field [0001] The invention belongs to the technical field of drop pill preparation, and in particular relates to a ginkgo drop pill and a preparation method thereof. Background technique [0002] Ginkgo biloba dripping pill is a traditional Chinese medicine preparation extracted from ginkgo biloba, which can treat various cardiovascular and cerebrovascular diseases. Ginkgo biloba dripping pill is a special drug for clinical treatment of chest obstruction, heartache, stroke, hemiplegia, tongue force, stable angina pectoris, cerebral infarction and other diseases. The unique mechanism of action of Ginkgo Leaf Dropping Pills is different from some commonly used drugs for the treatment of cardiovascular and cerebrovascular diseases in clinical practice. One is that ginkgolides can selectively resist platelet activating factor. Platelet activating factor is a strong endogenous active substance that can cause platelet aggregation and thrombus formation in the human bod...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K36/16A61K9/20A61P9/10A61P39/06A61P9/00A61K35/644
CPCA61K9/2027A61K9/2068A61K35/644A61K36/07A61K36/16A61K36/481A61K36/52A61K36/537A61K36/734A61K36/8969A61K2236/331A61P9/00A61P9/10A61P39/06A61K2300/00
Inventor 尹维涛郑秀文刘家领
Owner ANHUI SONGSHANTANG CHINESE HERBAL MEDICINE
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