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Nutrient composition with nerve protection effect and preparation method and application thereof

A nutritional composition and neuroprotection technology, applied in the directions of medical preparations containing active ingredients, applications, drug combinations, etc., can solve problems such as loss of activity, difficulty in practical application, etc., and achieve long action time, good stability, and simple combination. Effect

Active Publication Date: 2018-08-24
HARBIN INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention overcomes the problem that gamma-tocotrienol is easily oxidized and loses its activity when it is used alone, which makes it difficult to apply in practice, and provides a neuroprotective drug composed of gamma-tocotrienol and grape skin extract Nutritional composition formed with corn oil

Method used

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  • Nutrient composition with nerve protection effect and preparation method and application thereof
  • Nutrient composition with nerve protection effect and preparation method and application thereof
  • Nutrient composition with nerve protection effect and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1: The nutritional composition with neuroprotective effect in this example is made from the following raw materials by weight percentage: 0.1g gamma-tocotrienol, 1g grape skin extract and 98.9g corn oil; The following steps are achieved: γ-tocotrienol and corn oil are mechanically stirred at a speed of 500rpm at room temperature until uniform (stirring time is 10 to 30min); then grape skin extract is added and mechanically stirred at a speed of 500rpm at room temperature. Stir until uniform (stirring time is 10-30min).

[0026] The gamma-tocotrienol (purity content≥98%) used in this example was purchased from Cayman chemical company (USA);

[0027] The grape skin extract is prepared according to the following steps: extract twice with 95% (w / w) ethanol, combine the extracts, and then concentrate the extracts by rotary evaporation at 50°C to 1 / 20 of the original volume, Wash with an appropriate amount of deionized water into a plate, freeze at -20°C for 24h, and...

Embodiment 2

[0030] Example 2: The nutritional composition with neuroprotective effect in this example is made from the following raw materials by weight percentage: 0.2g gamma-tocotrienol, 2g grape skin extract and 97.8g corn oil; The following steps are achieved: γ-tocotrienol and corn oil are mechanically stirred at a speed of 500rpm at room temperature until uniform (stirring time is 10 to 30min); then grape skin extract is added and mechanically stirred at a speed of 500rpm at room temperature. Stir until uniform (stirring time is 10-30min).

[0031] Grape skin powder in Example 1 was provided by Joseph's Natural Products (Ontario, Canada). Grape skin extract was prepared according to the method in Example 1.

Embodiment 3

[0032] Example 3: The nutritional composition with neuroprotective effect in this example is made from the following raw materials by weight percentage: 0.4g gamma-tocotrienol, 5g grape skin extract and 94.6g corn oil; The following steps are achieved: γ-tocotrienol and corn oil are mechanically stirred at a speed of 500rpm at room temperature until uniform (stirring time is 10 to 30min); then grape skin extract is added and mechanically stirred at a speed of 500rpm at room temperature. Stir until uniform (stirring time is 10-30min).

[0033] The grape skin extract in this example was prepared according to the method of Example 1.

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Abstract

The invention discloses a nutrient composition with a nerve protection effect and a preparation method and application thereof and belongs to the technical fields of food and health care products. Thenutrient composition disclosed by the invention overcomes the problem that gamma-tocotrienol is easily oxidized and inactivated when being solely used so that the practical application of the gamma-tocotrienol is difficult. The nutrient composition disclosed by the invention is mainly prepared from the following raw materials in percentage by weight: 0.1%-1% of gamma-tocotrienol, 1%-20% of grapepeel extract and 79%-98.9% of corn oil. The preparation method comprises the following steps: uniformly mixing the gamma-tocotrienol and the corn oil; and then, adding the grape peel extract, and performing uniform mixing. The composition disclosed by the invention has the effects of protecting nerves, improving learning and memory abilities, relieving depression and the like. The composition disclosed by the invention enhances the stability of each functional component, can be easily stored for a long time, is simple in combination and is nutritional and free of side effects, so that the composition is suitable for being taken for a long time.

Description

technical field [0001] The invention belongs to the technical field of food and health products; in particular, it relates to a nutritional composition with neuroprotective effect and its preparation method and application. Background technique [0002] Stress is a state in which the body is under various pressures from the external environment (that is, stimulation by harmful factors), and a series of reactions that occur. Stress can cause people to have negative emotions such as tension, conflict, anxiety, depression, etc. If the body and mind are tense for a long time, it will cause normal physiological dysfunction, such as psychological imbalance, nervous system dysfunction, endocrine disorder, etc., and the body's immunity will decline , Physical fatigue, loss of appetite, sleep disturbance, etc. [0003] Stress often raises levels of the stress hormone, glucocorticoids. The hippocampus is particularly sensitive to the increase in the level of glucocorticoids, and lon...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P3/06A61P9/12A61P9/10A61P35/00A61P25/24A61P25/28A61P25/00A23L33/105A23L33/115A61K31/355
CPCA23V2002/00A61K31/355A61K36/87A61K36/899A61K2236/333A61K2236/39A23L33/105A23L33/115A61P3/06A61P9/10A61P9/12A61P25/00A61P25/24A61P25/28A61P35/00A61K2300/00A23V2200/30A23V2200/326A23V2200/3262A23V2250/21A23V2250/186A23V2250/1886
Inventor 徐伟丽杨洋刘蕾杨雨虹
Owner HARBIN INST OF TECH
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