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Hydrogel and process using hydrogel to produce cooling plaster

A hydrogel and aqueous solution technology, applied in the field of cooling paste production, can solve the problems of easy peeling of the gel part, poor adhesion between the gel and the skin, and difficulty in achieving cooling effects, and achieve moderate adhesion and peeling strength. The effect of good adhesion

Active Publication Date: 2018-08-17
杭州求是医学科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the gel part in the cooling patch is directly in contact with the skin of the human body. When the body temperature is too high, the sweat produced on the body surface will easily affect the gel part of the cooling patch directly adhered to the skin surface, thus causing the gel to separate from the skin. The adhesion effect between the skin is poor, which makes the gel part easier to be peeled off, making it difficult to achieve a long-term sustained and stable cooling effect

Method used

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  • Hydrogel and process using hydrogel to produce cooling plaster
  • Hydrogel and process using hydrogel to produce cooling plaster
  • Hydrogel and process using hydrogel to produce cooling plaster

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0074] Embodiment 1: A hydrogel, the components included and their corresponding parts by weight are shown in Table 1, and prepared by the following steps:

[0075] Step 1, fully dissolve the cooling agent in absolute alcohol to form a cool mixture, fully mix glycerin, resin powder, aluminum glycerol, and disodium edetate, and then fully mix with the cool mixture to form an oily mixture; Deionized water, 10wt% tartaric acid aqueous solution, and water-based preservative are fully mixed to form an aqueous mixture;

[0076] In step 2, the thickener is placed in the oily mixture obtained in step 1, fully mixed, and then fully mixed with the aqueous mixture obtained in step 1 to form a blend;

[0077] Step 3: Add polyvinylpyrrolidone to the blend obtained in Step 2 and mix thoroughly to obtain a hydrogel.

[0078] Wherein, the resin powder is HQ841; the thickener is crospovidone; the water-based preservative is DMDMH; the cooling agent is mint and borneol with a ratio of parts by...

Embodiment 2

[0079] Example 2: A hydrogel, the difference from Example 1 is that the components and their corresponding parts by weight are shown in Table 1. In step 1, the nano-microcrystalline cellulose colloid is thoroughly mixed with deionized water, 10 wt % tartaric acid aqueous solution, and a water-based preservative, and the nano-micro-crystalline cellulose colloid contains 0.1 wt % of nano-microcrystalline cellulose.

Embodiment 3-5

[0080] Example 3-5: A hydrogel, the difference from Example 1 is that the components and their corresponding parts by weight are shown in Table 1. In step 1, the nano-microcrystalline cellulose colloid is fully mixed with deionized water, 10wt% tartaric acid aqueous solution, and water-based preservative; the essential oil and 0.1wt% brilliant blue aqueous solution are added to step 3, and fully mixed.

[0081] Components included in Table 1 Embodiment 1-5 and their corresponding parts by weight

[0082]

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Abstract

The invention discloses hydrogel and a process using the hydrogel to produce a cooling plaster and belongs to the technical field of cooling plaster production. The hydrogel comprises 70-81 parts of glycerin, 11-18 parts of resin powder, 3.9-4.9 parts of thickening agent, 0.35-0.45 part of dihydroxyaluminum aminoacetate, 0.25-0.33 part of ethylenediamine tetraacetic acid disodium, 16-18 parts of polyvinyl pyrrolidone, 7.5-8.8 parts of 10wt% tartaric acid aqueous solution, 0.85-1 part of waterborne preservative, 1.0-1.25 parts of cooling agent, 1.6-1.9 parts of anhydrous alcohol and 170-200 parts of deionized water, wherein the resin powder comprises at least one of H106 and HQ841. The hydrogel is good in adhesiveness and stripping strength, is mild and non-irritant, and cannot easily damage the skin.

Description

technical field [0001] The invention relates to the technical field of cooling patch production, more specifically, it relates to a hydrogel and a process for making a cooling patch using the hydrogel. Background technique [0002] The cooling patch can be directly attached to the forehead or places that need cold compresses, instead of ice packs, which can cool down and cold compress, and make the operation more convenient. [0003] However, the gel part in the cooling patch is directly in contact with the skin of the human body. When the body temperature is too high, the sweat produced on the body surface will easily affect the gel part of the cooling patch directly adhered to the skin surface, thus causing the gel to separate from the skin. The adhesion effect between the skins is poor, which makes the gel part easier to be peeled off, making it difficult to achieve a long-term sustained and stable cooling effect. Contents of the invention [0004] In view of the defic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K47/10A61K47/32A61K47/18A61K47/12A61K9/70A61P29/00A61K36/534A61K31/045
CPCA61K9/0014A61K9/06A61K9/7023A61K31/045A61K36/534A61K47/10A61K47/12A61K47/183A61K47/32A61P29/00A61K2300/00
Inventor 陈航
Owner 杭州求是医学科技有限公司
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