Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Culture medium of hericium and Chinese yam bioconversion mycelium as well as extract of Chinese yam bioconversion mycelium and application thereof

A technology of biotransformation and Hericium erinaceus, applied in the direction of microorganism-based methods, biochemical equipment and methods, microorganisms, etc., can solve the problems of multiple complications, organ damage, etc., and achieve a good effect of lowering blood sugar

Inactive Publication Date: 2018-06-15
HUNAN XINHUI PHARMA
View PDF6 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although new oral hypoglycemic drugs continue to emerge, and insulin is widely used in clinical practice, the blood sugar of most diabetic patients is under control, but multiple complications and organ damage still plague people.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Culture medium of hericium and Chinese yam bioconversion mycelium as well as extract of Chinese yam bioconversion mycelium and application thereof
  • Culture medium of hericium and Chinese yam bioconversion mycelium as well as extract of Chinese yam bioconversion mycelium and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] An extract of yam biotransformation mycelium, its preparation method comprises the steps:

[0031] (1) Take 500g of yam, 400g of wheat bran, and 100g of rice bran, mix well, add 400g of water and mix well to obtain the culture medium. Then bottle, sterilize, insert Hericium erinaceus, transform and culture at 27°C for about 40 days, take out the mycelium, and dry it to obtain the yam biotransformation mycelium;

[0032] (2) Extracting the biotransformation mycelium of yam with water, soaking in water twice at 40° C. for 5 hours each time, the weight of the water is 6 times the weight of the biotransformation mycelium of yam, to obtain an extract;

[0033] (3) Concentrate the above-mentioned extract under reduced pressure at 50°C, freeze-dry the concentrated solution obtained under reduced pressure, freeze at -40°C for 4 hours, sublimate once at -10°C for 2 hours, sublimate at 0°C for 10 hours, and then sublimate at 30°C Sublimated three times for 24 hours to obtain the...

Embodiment 2

[0035]A kind of Chinese yam biotransformation mycelia extract, its preparation method comprises the steps:

[0036] (1) Take 600g of agricultural and sideline products yam, 300g of wheat bran, and 100g of rice bran, mix well, add 450g of water and mix well to obtain the culture medium. Then bottle, sterilize, insert Hericium erinaceus, transform and culture at 27°C for about 40 days, take out the mycelium, and dry it to obtain the yam biotransformation mycelium;

[0037] (2) extracting the biotransformed mycelium of Chinese yam with water, soaking in water twice at 50° C. for 4 hours each time, the weight of the water being 8 times the weight of the biotransformed mycelium of Chinese yam, and obtaining an extract;

[0038] (3) Concentrate the above extract under reduced pressure at 50°C, freeze-dry the concentrated solution obtained under reduced pressure, freeze at -40°C for 5 hours, sublimate once at -10°C for 3 hours, sublimate at 0°C for 6 hours, and then sublimate at 30°C...

Embodiment 3

[0040] A kind of Chinese yam biotransformation mycelia extract, its preparation method comprises the steps:

[0041] (1) Take 700g of agricultural and sideline products yam, 200g of wheat bran, and 100g of rice bran, mix them evenly, add 500g of water and mix well to obtain the culture medium. Then bottle, sterilize, insert Hericium erinaceus, transform and culture at 27°C for about 40 days, take out the mycelium, and dry it to obtain the yam biotransformation mycelium;

[0042] (2) Extracting the biotransformation mycelium of yam with water, soaking in water at 60° C. for 3 times, each soaking for 2 hours, the weight of the water being 10 times the weight of the biotransformation mycelium of yam, to obtain an extract;

[0043] (3) Concentrate the above extract under reduced pressure at 50°C, freeze-dry the concentrated solution obtained under reduced pressure, freeze at -40°C for 6 hours, sublimate once at -10°C for 5 hours, sublimate at 0°C for 5 hours, and then sublimate at...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a culture medium of hericium and Chinese yam bioconversion mycelium as well as an extract of the Chinese yam bioconversion mycelium and application thereof. The culture mediumof the hericium comprises the following components in parts by weight: 490-350 parts of Chinese yam, 140-100 parts of wheat bran, 70-50 parts of cavings and 400-600 parts of water. The Chinese yam bioconversion mycelium is a product obtained by introducing the hericium into the culture medium and performing mycelial transformation culture. The extract of the Chinese yam bioconversion mycelium is prepared by performing water extraction on hericium mycelium, then concentrating under reduced pressure and finally performing vacuum freeze-drying. The extract of the Chinese yam bioconversion mycelium has a hypoglycemic effect and can be used for preparing hypoglycemic health products or drugs.

Description

technical field [0001] The invention relates to the technical field of biopharmaceuticals, in particular to a culture medium of Hericium erinaceus, yam biotransformation mycelia, an extract of yam biotransformation mycelia and uses thereof. Background technique [0002] Hericium erinaceus, a mushroom (fungi) of the family Hericium erinaceae, has been used in traditional Chinese medicine to treat gastrointestinal diseases for more than 2,000 years. A series of small molecule compounds, such as erinacines, are believed to have nerve regeneration and can pass through The blood-brain barrier repairs damaged nervous tissue. Hericium erinaceus also has anti-ulcer, anti-inflammatory, anti-microbial, immune regulation, improving liver function, anti-aging, lowering blood sugar and blood lipids, improving anti-hypoxia ability, increasing cardiac output, and improving circulation, etc., including Hericium erinaceus The medical preparations of are widely used in China. [0003] The m...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/14A61K36/07A61K36/8945A61P3/10A01G18/20A01G18/40A23L31/00A23L33/00C12R1/645
Inventor 何述金周代俊贺雄威曹斯琪
Owner HUNAN XINHUI PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com