Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method for extracting purified hydroxy citric acid from garcinia cambogia

A technology for purifying hydroxycitric acid and hydroxycitric acid, which is applied in the field of phytochemistry, can solve the problems of high production cost, low proportion of 2-hydroxycitric acid monomer compound, and many operating procedures, and achieve low cost, convenient and efficient acquisition, The effect of simple process

Inactive Publication Date: 2018-05-18
NANJING HOPE PHARM +1
View PDF5 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the above-mentioned patents for preparing hydroxycitric acid from garcinia cambogia, there are many operating procedures, the proportion of available 2-hydroxycitric acid monomer compounds is low, and there are technical problems such as high production costs.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method for extracting purified hydroxy citric acid from garcinia cambogia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Pulverize the garcinia cambogia fruit, put it into a multi-stage countercurrent extraction device, add 4 times the volume of 2% ethanol-water solution for countercurrent extraction for 5 hours, filter after extraction, add the filtrate to a neutralization kettle, and add 1 equivalent of Calcium hydroxide aqueous solution, adjust the pH value at 7.5, stir and heat to 85 ° C, continue to stir for 2 hours, cool to at least room temperature, use an ion machine to centrifuge, wash with water to obtain the crude calcium hydroxycitrate,

[0026] Add the crude calcium hydroxycitrate to the purification kettle, add 4 times the volume of deionized water, stir, heat to 100°C, stir at 100°C for 1 hour, cool to room temperature, and perform a second centrifugation to obtain hydroxycitric acid calcium;

[0027] Add the above-mentioned purified calcium hydroxycitrate product into the acidification kettle, add 3 times the volume of deionized water, add 20% dilute sulfuric acid dropwise...

Embodiment 2

[0029] Pulverize the Garcinia cambogia fruit, put it into a multi-stage countercurrent extraction device, add 10 times the volume of 15% ethanol-water solution for countercurrent extraction for 8 hours, filter after extraction, add the filtrate to the neutralization kettle, and add 1.5 equivalents of Calcium oxide, adjust the pH value at 8.0, stir and heat to 75 ° C, continue to stir for 4 hours, cool to at least room temperature, use an ion machine to centrifuge, wash with water to obtain crude calcium hydroxycitrate,

[0030] Add the crude calcium hydroxycitrate to the purification kettle, add 8 times the volume of deionized water, stir, heat to 90°C, stir at 90°C for 2 hours, cool to room temperature, and perform a second centrifugation to obtain hydroxycitric acid calcium;

[0031] Add the above-mentioned purified calcium hydroxycitrate product into the acidification kettle, add 6 times the volume of deionized water, add 30% acid dropwise under stirring until the pH value ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a preparation method for extracting purified hydroxy citric acid from garcinia cambogia. The method comprises the steps that the garcinia cambogia is crushed, an alcohol-watersolution is added, multistage counter-current extraction is conducted, after an extracting solution is filtered, calcium oxide or calcium hydroxide is used for conducting neutralization, and calcium hydroxy citrate is obtained; the calcium hydroxy citrate is subjected to purification, acidolysis, membrane separation and desolvation, and high-purity hydroxy citric acid is obtained. Due to the factthat the calcium hydroxy citrate is small in solubility in water, the pure calcium hydroxy citrate is obtained through preparation, acidolysis and membrane separation are conducted, and the hydroxy citric acid with the content being 92% or above can be obtained. The technology is simple, operation is easy and convenient, the cost is low, and the method is suitable for batch production.

Description

technical field [0001] The invention relates to a preparation method for extracting and purifying hydroxycitric acid from garcinia cambogia, belonging to the technical field of phytochemistry. Background technique [0002] Garcinia cambogia (Garcinia cambogia), also known as Malabar tamarind, is a dicotyledonous tree of Garcinia cambogia. The fruit of Garcinia cambogia is about the same size as an orange, and its outer surface is similar to a pumpkin. Native to South Asia, it grows in moist forests on low hills and is currently widely planted in India and Thailand. Modern pharmacological research shows that garcinia cambogia contains a large amount of hydroxycitric acid (Hydroxycitric acid, HCA), inhibits fat synthesis, promotes fat burning in the body, regulates fat metabolism in the human body, increases the ability of liver and muscle to store glycogen, and reduces fat production; it can also be used It is used to treat intestinal discomfort, inhibit bacterial growth, et...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07C51/42C07C59/245
CPCC07C51/42C07C59/245
Inventor 徐德锋徐华
Owner NANJING HOPE PHARM
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com